SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hbq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 4hbq MUCOSAL ADDRESSIN
CELL ADHESION
MOLECULE 1
(Homo
sapiens) 		5 / 11 ALA A 139
LEU A 129
LEU A 103
SER A  99
ALA A 111
 None
 1.13A 1h9zA-4hbqA:
undetectable		 1h9zA-4hbqA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 4hbq MUCOSAL ADDRESSIN
CELL ADHESION
MOLECULE 1
(Homo
sapiens) 		5 / 12 LEU A 172
PRO A 177
PRO A 178
GLY A 132
GLY A 133
 None
 0.88A 2uvnA-4hbqA:
undetectable		 2uvnA-4hbqA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 4hbq MUCOSAL ADDRESSIN
CELL ADHESION
MOLECULE 1
(Homo
sapiens) 		5 / 9 LEU A 129
LEU A 103
ILE A 199
SER A  99
ALA A 111
 None
 1.20A 4z69A-4hbqA:
undetectable		 4z69A-4hbqA:
15.46