SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hci'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 4 HIS A  79
CYH A 114
HIS A 117
MET A 122
 None
 0.65A 1oe1A-4hciA:
5.8		 1oe1A-4hciA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 5 HIS A  79
CYH A 114
HIS A 117
MET A 122
 None
 0.62A 1oe2A-4hciA:
9.6		 1oe2A-4hciA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 4 HIS A  79
CYH A 114
HIS A 117
MET A 122
 None
 0.61A 1oe3A-4hciA:
5.7		 1oe3A-4hciA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		5 / 9 LEU A  69
ILE A 127
PRO A  56
VAL A  47
ILE A  45
 None
 1.10A 2avoA-4hciA:
undetectable		 2avoA-4hciA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 4 HIS A  79
CYH A 114
HIS A 117
MET A 122
 None
 0.59A 2fqdA-4hciA:
4.1		 2fqdA-4hciA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 4 HIS A  79
CYH A 114
HIS A 117
MET A 122
 None
 0.57A 2fqeA-4hciA:
4.1		 2fqeA-4hciA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 4 HIS A  79
CYH A 114
HIS A 117
MET A 122
 None
 0.59A 2fqfA-4hciA:
4.1		 2fqfA-4hciA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 4 HIS A  79
CYH A 114
HIS A 117
MET A 122
 None
 0.59A 2fqgA-4hciA:
4.1		 2fqgA-4hciA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		5 / 9 GLY A 124
VAL A  47
PRO A  56
ILE A  45
VAL A  44
 None
 1.25A 2nnhB-4hciA:
undetectable		 2nnhB-4hciA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 8 HIS A  79
ASP A  51
HIS A 117
ASP A  52
 None
 1.11A 2xadA-4hciA:
undetectable		 2xadA-4hciA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 8 HIS A  79
ASP A  51
HIS A 117
ASP A  52
 None
 1.09A 2xadC-4hciA:
undetectable		 2xadC-4hciA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 8 HIS A  79
ASP A  51
HIS A 117
ASP A  52
 None
 1.12A 2xadD-4hciA:
undetectable		 2xadD-4hciA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 4 HIS A  79
CYH A 114
HIS A 117
MET A 122
 None
 0.59A 2xxgA-4hciA:
9.6		 2xxgA-4hciA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 5 HIS A  79
CYH A 114
HIS A 117
MET A 122
 None
 0.64A 2xxgC-4hciA:
9.5		 2xxgC-4hciA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 7 VAL A 102
VAL A  90
PHE A  81
ILE A  59
 None
 0.92A 3zjqA-4hciA:
undetectable		 3zjqA-4hciA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 7 VAL A 102
VAL A  90
PHE A  81
ILE A  59
 None
 0.93A 3zjqB-4hciA:
undetectable		 3zjqB-4hciA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 4 HIS A  79
CYH A 114
HIS A 117
MET A 122
 None
 0.62A 4ef3A-4hciA:
3.9		 4ef3A-4hciA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 6 ASP A  51
ASP A  52
HIS A  79
HIS A 117
 None
 0.92A 5ncdB-4hciA:
undetectable
5ncdC-4hciA:
undetectable		 5ncdB-4hciA:
16.60
5ncdC-4hciA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 8 ASP A  51
ASP A  52
HIS A  79
HIS A 117
 None
 1.00A 5nekB-4hciA:
undetectable		 5nekB-4hciA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		4 / 6 ASP A  51
ASP A  52
HIS A  79
HIS A 117
 None
 0.93A 5nelA-4hciA:
undetectable
5nelD-4hciA:
undetectable		 5nelA-4hciA:
16.60
5nelD-4hciA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4hci CUPREDOXIN 1
(Bacillus
anthracis) 		5 / 9 VAL A 102
LEU A  69
PHE A  81
VAL A 126
ILE A  61
 None
 1.15A 5om2A-4hciA:
undetectable
5om2B-4hciA:
undetectable		 5om2A-4hciA:
18.75
5om2B-4hciA:
15.00