SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hcx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 7 THR A 283
GLY A 277
ASP A 276
TYR A 275
 None
 0.98A 1bu5A-4hcxA:
2.2		 1bu5A-4hcxA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 7 GLY A 277
THR A 109
HIS A 136
SER A 199
 None
 0.78A 1c9sT-4hcxA:
undetectable
1c9sU-4hcxA:
undetectable		 1c9sT-4hcxA:
11.49
1c9sU-4hcxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 7 GLY A 277
THR A 109
HIS A 136
SER A 199
 None
 0.88A 1gtfL-4hcxA:
undetectable
1gtfM-4hcxA:
undetectable		 1gtfL-4hcxA:
11.49
1gtfM-4hcxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 8 GLY A 277
THR A 109
HIS A 136
SER A 199
 None
 0.87A 1gtfN-4hcxA:
undetectable
1gtfO-4hcxA:
undetectable		 1gtfN-4hcxA:
11.49
1gtfO-4hcxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 6 GLY A  71
THR A 300
THR A 305
ILE A  67
 None
 0.92A 1gtnD-4hcxA:
undetectable
1gtnE-4hcxA:
undetectable		 1gtnD-4hcxA:
11.49
1gtnE-4hcxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 7 GLY A  71
THR A 300
THR A 305
ILE A  67
 None
 0.90A 1gtnF-4hcxA:
undetectable
1gtnG-4hcxA:
undetectable		 1gtnF-4hcxA:
11.49
1gtnG-4hcxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 7 GLY A  71
THR A 300
THR A 305
ILE A  67
 None
 0.91A 1gtnJ-4hcxA:
undetectable
1gtnK-4hcxA:
undetectable		 1gtnJ-4hcxA:
11.49
1gtnK-4hcxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 6 TYR A 202
GLU A 363
ILE A 131
GLY A 134
 None
 0.95A 1maaB-4hcxA:
undetectable
1maaD-4hcxA:
undetectable		 1maaB-4hcxA:
21.84
1maaD-4hcxA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 8 ILE A  34
LEU A  38
LYS A 348
GLY A 347
 None
 0.92A 1os6A-4hcxA:
undetectable		 1os6A-4hcxA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 5 GLU A  15
TYR A  44
SER A 335
ASP A  31
 None
 1.11A 1vidA-4hcxA:
undetectable		 1vidA-4hcxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		5 / 11 GLU A 190
GLY A 108
GLY A 107
ILE A 192
ALA A 137
 None
 0.94A 1x7pA-4hcxA:
undetectable
1x7pB-4hcxA:
undetectable		 1x7pA-4hcxA:
22.64
1x7pB-4hcxA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOW_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 337
GLU A 363
GLN A 344
TYR A 202
 None
 1.40A 2aowA-4hcxA:
undetectable		 2aowA-4hcxA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 8 PHE A 337
GLU A 363
GLN A 344
TYR A 202
 None
 1.48A 2aoxA-4hcxA:
undetectable		 2aoxA-4hcxA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_B_THAB401_1
(HISTAMINE
N-METHYLTRANSFERASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 337
GLU A 363
GLN A 344
TYR A 202
 None
 1.49A 2aoxB-4hcxA:
undetectable		 2aoxB-4hcxA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		3 / 3 GLY A  48
GLU A  50
ASP A  17
 None
 0.61A 2b25B-4hcxA:
undetectable		 2b25B-4hcxA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 6 GLU A  15
TYR A  44
SER A 335
ASP A  31
 None
 1.10A 2cl5B-4hcxA:
undetectable		 2cl5B-4hcxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		5 / 9 GLU A  50
ILE A  49
GLU A  88
GLU A  20
ILE A  79
 None
None
None
None
NDP  A 502 (-3.9A)
 1.27A 2j9dA-4hcxA:
undetectable
2j9dB-4hcxA:
undetectable
2j9dC-4hcxA:
0.1		 2j9dA-4hcxA:
15.93
2j9dB-4hcxA:
15.93
2j9dC-4hcxA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		5 / 9 GLU A  88
GLU A  20
ILE A  79
GLU A  50
ILE A  49
 None
None
NDP  A 502 (-3.9A)
None
None
 1.29A 2j9dA-4hcxA:
undetectable
2j9dB-4hcxA:
undetectable
2j9dC-4hcxA:
0.1		 2j9dA-4hcxA:
15.93
2j9dB-4hcxA:
15.93
2j9dC-4hcxA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		5 / 10 GLU A  50
ILE A  49
GLU A  88
GLU A  20
ILE A  79
 None
None
None
None
NDP  A 502 (-3.9A)
 1.29A 2j9dD-4hcxA:
undetectable
2j9dE-4hcxA:
undetectable
2j9dF-4hcxA:
undetectable		 2j9dD-4hcxA:
15.93
2j9dE-4hcxA:
16.14
2j9dF-4hcxA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		5 / 10 GLU A  88
GLU A  20
ILE A  79
GLU A  50
ILE A  49
 None
None
NDP  A 502 (-3.9A)
None
None
 1.28A 2j9dD-4hcxA:
undetectable
2j9dE-4hcxA:
undetectable
2j9dF-4hcxA:
undetectable		 2j9dD-4hcxA:
15.93
2j9dE-4hcxA:
16.14
2j9dF-4hcxA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		5 / 9 GLU A  50
ILE A  49
GLU A  88
GLU A  20
ILE A  79
 None
None
None
None
NDP  A 502 (-3.9A)
 1.25A 2j9dG-4hcxA:
undetectable
2j9dH-4hcxA:
undetectable
2j9dI-4hcxA:
undetectable		 2j9dG-4hcxA:
15.93
2j9dH-4hcxA:
15.93
2j9dI-4hcxA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		3 / 3 SER A 199
HIS A 251
ASP A 255
 None
 0.72A 2oxtA-4hcxA:
undetectable		 2oxtA-4hcxA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 5 SER A 199
GLY A 134
HIS A 251
ASP A 255
 None
 1.15A 2oxtB-4hcxA:
undetectable		 2oxtB-4hcxA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 8 ARG A  23
ASP A  46
LEU A  47
GLY A  18
 None
 0.91A 2qqdB-4hcxA:
undetectable
2qqdC-4hcxA:
undetectable		 2qqdB-4hcxA:
17.93
2qqdC-4hcxA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  47
LEU A  16
SER A  97
PRO A  98
GLY A 100
 None
 1.01A 2vmyA-4hcxA:
undetectable		 2vmyA-4hcxA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		3 / 3 MET A  94
VAL A  59
GLU A  50
 None
 0.88A 2x9gA-4hcxA:
undetectable		 2x9gA-4hcxA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 8 VAL A  72
VAL A   9
HIS A 345
VAL A 306
 None
 0.96A 3fhxB-4hcxA:
3.4		 3fhxB-4hcxA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI201_1
(PROTEIN S100-A4)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 203
GLY A 267
ILE A 133
CYH A 272
PHE A 230
 None
 1.44A 3ko0H-4hcxA:
undetectable
3ko0I-4hcxA:
undetectable		 3ko0H-4hcxA:
13.79
3ko0I-4hcxA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 8 ILE A  34
LEU A  38
LYS A 348
GLY A 347
 None
 0.92A 3selX-4hcxA:
undetectable		 3selX-4hcxA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 6 ASP A  17
GLY A  48
ASP A  19
THR A  78
 None
None
None
NDP  A 502 (-3.9A)
 0.90A 3vqrA-4hcxA:
undetectable		 3vqrA-4hcxA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 5 ASP A  17
GLY A  48
ASP A  19
THR A  78
 None
None
None
NDP  A 502 (-3.9A)
 0.92A 3vqrB-4hcxA:
undetectable		 3vqrB-4hcxA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  34
LEU A  38
LYS A 348
GLY A 347
 None
 0.82A 4hbfA-4hcxA:
undetectable		 4hbfA-4hcxA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  34
LEU A  38
LYS A 348
GLY A 347
 None
 0.93A 4hc3A-4hcxA:
undetectable		 4hc3A-4hcxA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  48
GLY A  18
THR A  22
ASP A  46
ILE A  49
 None
 1.10A 4pghA-4hcxA:
undetectable		 4pghA-4hcxA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		5 / 11 ASP A 397
VAL A  24
ILE A  25
ALA A 400
ILE A 399
 None
 1.02A 5d75A-4hcxA:
undetectable		 5d75A-4hcxA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 8 SER A 199
GLY A 277
THR A 109
HIS A 136
 None
 0.87A 5eezL-4hcxA:
undetectable
5eezV-4hcxA:
undetectable		 5eezL-4hcxA:
11.49
5eezV-4hcxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 8 SER A 199
GLY A 277
THR A 109
HIS A 136
 None
 0.87A 5ef1L-4hcxA:
undetectable
5ef1V-4hcxA:
undetectable		 5ef1L-4hcxA:
11.49
5ef1V-4hcxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 8 SER A 199
GLY A 277
THR A 109
HIS A 136
 None
 0.87A 5ef2L-4hcxA:
undetectable
5ef2V-4hcxA:
undetectable		 5ef2L-4hcxA:
11.49
5ef2V-4hcxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		4 / 5 GLU A  15
TYR A  44
SER A 335
ASP A  31
 None
 1.07A 5fhrA-4hcxA:
undetectable		 5fhrA-4hcxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 4hcx ISOCITRATE
DEHYDROGENASE [NADP]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A 136
LYS A 273
PHE A 226
 None
 1.21A 5klaA-4hcxA:
undetectable		 5klaA-4hcxA:
22.78