SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hde'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 4hde SCO1/SENC FAMILY
LIPOPROTEIN
(Bacillus
anthracis) 		4 / 6 TYR A 163
VAL A 101
ILE A 136
LEU A  37
 None
 1.04A 1j96A-4hdeA:
undetectable		 1j96A-4hdeA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 4hde SCO1/SENC FAMILY
LIPOPROTEIN
(Bacillus
anthracis) 		4 / 7 TYR A 163
VAL A 101
ILE A 136
LEU A  37
 None
 1.00A 1j96B-4hdeA:
undetectable		 1j96B-4hdeA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NR3_A_95EA401_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3B)		 4hde SCO1/SENC FAMILY
LIPOPROTEIN
(Bacillus
anthracis) 		4 / 7 ILE A 115
PHE A 114
TRP A 125
ASP A  63
 None
 1.42A 5nr3A-4hdeA:
undetectable		 5nr3A-4hdeA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hde SCO1/SENC FAMILY
LIPOPROTEIN
(Bacillus
anthracis) 		4 / 6 LYS A  58
GLN A  95
PHE A  96
LEU A 164
 None
 1.31A 6nmpC-4hdeA:
undetectable
6nmpJ-4hdeA:
undetectable		 6nmpC-4hdeA:
17.79
6nmpJ-4hdeA:
19.85