SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hec'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 4hec -
(-) 		3 / 3 ARG A  67
GLY A 105
PRO A 106
 None
 0.74A 2hreD-4hecA:
undetectable		 2hreD-4hecA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 4hec -
(-) 		3 / 3 VAL A   2
PHE A   5
ARG A 155
 None
 0.87A 4xr4B-4hecA:
undetectable		 4xr4B-4hecA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4hec -
(-) 		4 / 8 ASP A 146
ASP A 149
TRP A  91
ARG A 122
 None
 0.98A 5nekB-4hecA:
undetectable		 5nekB-4hecA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 4hec -
(-) 		4 / 5 ALA A  94
TYR A  95
GLN A 102
ILE A  17
 None
 1.39A 6g9bA-4hecA:
undetectable
6g9bB-4hecA:
undetectable		 6g9bA-4hecA:
20.89
6g9bB-4hecA:
15.64