SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hei'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 4hei RIBOSOME HIBERNATION
PROTEIN YHBH
(Vibrio
cholerae) 		5 / 12 ILE A   3
LEU A  27
PHE A  24
LYS A  23
LEU A  77
 None
 1.05A 1dyiA-4heiA:
undetectable		 1dyiA-4heiA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 4hei RIBOSOME HIBERNATION
PROTEIN YHBH
(Vibrio
cholerae) 		5 / 12 ILE A   3
LEU A  27
PHE A  24
LYS A  23
LEU A  77
 None
 1.07A 1dyiB-4heiA:
undetectable		 1dyiB-4heiA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)		 4hei RIBOSOME HIBERNATION
PROTEIN YHBH
(Vibrio
cholerae) 		5 / 12 ILE A   3
LEU A  27
PHE A  24
LYS A  23
LEU A  77
 None
 1.15A 1jolB-4heiA:
undetectable		 1jolB-4heiA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 4hei RIBOSOME HIBERNATION
PROTEIN YHBH
(Vibrio
cholerae) 		5 / 12 ILE A   3
LEU A  27
PHE A  24
LYS A  23
LEU A  77
 None
 1.00A 1rd7A-4heiA:
undetectable		 1rd7A-4heiA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 4hei RIBOSOME HIBERNATION
PROTEIN YHBH
(Vibrio
cholerae) 		5 / 12 ILE A   3
LEU A  27
PHE A  24
LYS A  23
LEU A  77
 None
 1.04A 1rh3A-4heiA:
undetectable		 1rh3A-4heiA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_1
(DIHYDROFOLATE
REDUCTASE)		 4hei RIBOSOME HIBERNATION
PROTEIN YHBH
(Vibrio
cholerae) 		5 / 12 ILE A   3
LEU A  27
PHE A  24
LYS A  23
LEU A  77
 None
 1.15A 3ia4D-4heiA:
undetectable		 3ia4D-4heiA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 4hei RIBOSOME HIBERNATION
PROTEIN YHBH
(Vibrio
cholerae) 		5 / 12 ILE A   3
LEU A  27
PHE A  24
LYS A  23
LEU A  77
 None
 1.09A 4qlgB-4heiA:
undetectable		 4qlgB-4heiA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RGC_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4hei RIBOSOME HIBERNATION
PROTEIN YHBH
(Vibrio
cholerae) 		5 / 12 ILE A   3
LEU A  27
PHE A  24
LYS A  23
LEU A  77
 None
 0.98A 4rgcA-4heiA:
undetectable		 4rgcA-4heiA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4hei RIBOSOME HIBERNATION
PROTEIN YHBH
(Vibrio
cholerae) 		5 / 12 ILE A   3
LEU A  27
PHE A  24
LYS A  23
LEU A  77
 None
 1.12A 4x5fA-4heiA:
undetectable		 4x5fA-4heiA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4hei RIBOSOME HIBERNATION
PROTEIN YHBH
(Vibrio
cholerae) 		5 / 12 ILE A   3
LEU A  27
PHE A  24
LYS A  23
LEU A  77
 None
 1.13A 4x5gA-4heiA:
undetectable		 4x5gA-4heiA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5H_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4hei RIBOSOME HIBERNATION
PROTEIN YHBH
(Vibrio
cholerae) 		5 / 12 ILE A   3
LEU A  27
PHE A  24
LYS A  23
LEU A  77
 None
 1.12A 4x5hA-4heiA:
undetectable		 4x5hA-4heiA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4hei RIBOSOME HIBERNATION
PROTEIN YHBH
(Vibrio
cholerae) 		4 / 6 LEU A  27
PHE A  31
ASP A  32
HIS A  88
 None
 1.20A 5om3A-4heiA:
undetectable
5om3B-4heiA:
undetectable		 5om3A-4heiA:
21.88
5om3B-4heiA:
19.61