SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hes'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 10 ASP A 118
GLY A  93
ARG A  88
ILE A 120
GLY A  91
 None
 1.16A 1fohA-4hesA:
undetectable		 1fohA-4hesA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 10 ASP A 118
GLY A  93
ARG A  88
ILE A 120
GLY A  91
 None
 1.13A 1fohB-4hesA:
undetectable		 1fohB-4hesA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 10 ASP A 118
GLY A  93
ARG A  88
ILE A 120
GLY A  91
 None
 1.10A 1fohC-4hesA:
undetectable		 1fohC-4hesA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_D_IPHD802_0
(PHENOL HYDROXYLASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 10 ASP A 118
GLY A  93
ARG A  88
ILE A 120
GLY A  91
 None
 1.13A 1fohD-4hesA:
undetectable		 1fohD-4hesA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		7 / 12 ALA A  55
SER A  56
LYS A  59
SER A 117
ASN A 119
LYS A 217
GLY A 219
 None
GOL  A 301 (-3.0A)
GOL  A 301 ( 4.2A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.5A)
 0.35A 1ghmA-4hesA:
26.3		 1ghmA-4hesA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		7 / 12 ALA A  55
SER A  56
LYS A  59
SER A 117
ASN A 119
LYS A 217
GLY A 219
 None
GOL  A 301 (-3.0A)
GOL  A 301 ( 4.2A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.5A)
 0.38A 1i2wA-4hesA:
27.8		 1i2wA-4hesA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		6 / 12 ALA A  55
SER A  56
LYS A  59
SER A 117
ASN A 119
GLY A 219
 None
GOL  A 301 (-3.0A)
GOL  A 301 ( 4.2A)
GOL  A 301 (-2.7A)
None
GOL  A 301 (-3.5A)
 0.33A 1i2wB-4hesA:
27.7		 1i2wB-4hesA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGL_L_ESTL911_1
(IG GAMMA-1-CHAIN
IG KAPPA-CHAIN)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 10 GLN A  74
TYR A  65
LEU A 129
TYR A 106
HIS A  68
 GOL  A 302 (-3.8A)
None
None
None
GOL  A 302 (-4.0A)
 1.44A 1jglH-4hesA:
undetectable
1jglL-4hesA:
undetectable		 1jglH-4hesA:
17.86
1jglL-4hesA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 10 ASP A 118
GLY A  93
ARG A  88
ILE A 120
GLY A  91
 None
 1.13A 1pn0C-4hesA:
undetectable		 1pn0C-4hesA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 10 ASP A 118
GLY A  93
ARG A  88
ILE A 120
GLY A  91
 None
 1.13A 1pn0D-4hesA:
1.7		 1pn0D-4hesA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 12 LEU A 174
LEU A 171
ILE A  62
THR A 122
HIS A 216
 None
 1.22A 1tw4B-4hesA:
1.0		 1tw4B-4hesA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		3 / 3 LEU A 129
LEU A  61
MET A 113
 None
 0.63A 1ya3B-4hesA:
undetectable		 1ya3B-4hesA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		6 / 12 SER A  56
LYS A  59
SER A 117
ASN A 119
LYS A 217
GLY A 219
 GOL  A 301 (-3.0A)
GOL  A 301 ( 4.2A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.5A)
 0.37A 1ymxA-4hesA:
29.4		 1ymxA-4hesA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		6 / 12 SER A  56
LYS A  59
SER A 117
ASN A 119
LYS A 217
GLY A 219
 GOL  A 301 (-3.0A)
GOL  A 301 ( 4.2A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.5A)
 0.35A 1ymxB-4hesA:
29.5		 1ymxB-4hesA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 12 LEU A 171
LEU A 243
MET A 244
GLY A 256
LEU A 204
 None
 0.99A 2ouzA-4hesA:
undetectable		 2ouzA-4hesA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		3 / 3 TYR A 106
VAL A 128
THR A  80
 None
 0.83A 2ygnA-4hesA:
undetectable		 2ygnA-4hesA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		4 / 7 ILE A  43
ILE A  18
LEU A 271
LEU A 204
 None
 0.87A 3adxA-4hesA:
undetectable		 3adxA-4hesA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 12 LEU A 171
GLY A 228
ASP A 246
ILE A 247
TYR A 175
 None
 1.22A 3eeoA-4hesA:
undetectable		 3eeoA-4hesA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		4 / 6 GLY A 130
THR A 122
GLU A 132
GLU A 147
 None
 1.05A 3fpjA-4hesA:
undetectable		 3fpjA-4hesA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 12 LYS A  59
SER A 117
ASN A 119
LYS A 217
GLY A 219
 GOL  A 301 ( 4.2A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.5A)
 0.35A 3hlwA-4hesA:
29.4		 3hlwA-4hesA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 12 SER A 117
ASN A 119
LYS A 217
THR A 218
GLY A 219
 GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.7A)
GOL  A 301 (-3.5A)
 0.31A 3hlwB-4hesA:
29.5		 3hlwB-4hesA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 12 LYS A  59
ASN A 119
LYS A 217
THR A 218
GLY A 219
 GOL  A 301 ( 4.2A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.7A)
GOL  A 301 (-3.5A)
 0.30A 3huoA-4hesA:
29.5		 3huoA-4hesA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		6 / 12 ALA A  55
SER A  56
LYS A  59
ASN A 119
THR A 218
GLY A 219
 None
GOL  A 301 (-3.0A)
GOL  A 301 ( 4.2A)
None
GOL  A 301 (-3.7A)
GOL  A 301 (-3.5A)
 0.45A 3mzeA-4hesA:
21.9		 3mzeA-4hesA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		6 / 12 LYS A  59
SER A 117
ASN A 119
LYS A 217
GLY A 219
SER A 220
 GOL  A 301 ( 4.2A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.5A)
GOL  A 301 (-4.8A)
 0.31A 3q07A-4hesA:
29.5		 3q07A-4hesA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 12 LYS A  59
SER A 117
ASN A 119
LYS A 217
GLY A 219
 GOL  A 301 ( 4.2A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.5A)
 0.43A 3q07B-4hesA:
29.2		 3q07B-4hesA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 12 VAL A 143
ILE A 134
GLU A  64
ILE A 178
TYR A 175
 None
 1.47A 3q5pA-4hesA:
undetectable		 3q5pA-4hesA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		7 / 12 ALA A  55
SER A  56
SER A 117
ASN A 119
LYS A 217
THR A 218
GLY A 219
 None
GOL  A 301 (-3.0A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.7A)
GOL  A 301 (-3.5A)
 0.36A 3sh8A-4hesA:
27.9		 3sh8A-4hesA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		7 / 12 ALA A  55
SER A  56
LYS A  59
SER A 117
ASN A 119
LYS A 217
GLY A 219
 None
GOL  A 301 (-3.0A)
GOL  A 301 ( 4.2A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.5A)
 0.31A 3sh8B-4hesA:
27.6		 3sh8B-4hesA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 11 ALA A  44
LEU A  14
GLY A 260
ILE A  27
VAL A 267
 None
 1.06A 3zosA-4hesA:
undetectable
3zosB-4hesA:
undetectable		 3zosA-4hesA:
22.29
3zosB-4hesA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		3 / 3 ARG A 182
ARG A 189
TRP A 192
 None
 1.19A 4b7nA-4hesA:
undetectable		 4b7nA-4hesA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		3 / 3 ARG A 182
ARG A 189
TRP A 192
 None
 1.28A 4cpzC-4hesA:
undetectable		 4cpzC-4hesA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		3 / 3 ARG A 182
ARG A 189
TRP A 192
 None
 1.26A 4cpzE-4hesA:
undetectable		 4cpzE-4hesA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		3 / 3 ARG A 182
ARG A 189
TRP A 192
 None
 1.22A 4cpzF-4hesA:
undetectable		 4cpzF-4hesA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		3 / 3 ARG A 182
ARG A 189
TRP A 192
 None
 1.18A 4cpzG-4hesA:
undetectable		 4cpzG-4hesA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		3 / 3 ARG A 182
ARG A 189
TRP A 192
 None
 1.24A 4cpzH-4hesA:
undetectable		 4cpzH-4hesA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		6 / 12 LYS A  59
SER A 117
ASN A 119
LYS A 217
THR A 218
GLY A 219
 GOL  A 301 ( 4.2A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.7A)
GOL  A 301 (-3.5A)
 0.41A 4euzA-4hesA:
29.1		 4euzA-4hesA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		6 / 10 SER A 117
ASN A 119
LYS A 217
THR A 218
GLY A 219
ALA A  55
 GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.7A)
GOL  A 301 (-3.5A)
None
 1.50A 4fh2A-4hesA:
28.4		 4fh2A-4hesA:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		7 / 12 ALA A  55
SER A  56
SER A 117
ASN A 119
LYS A 217
THR A 218
GLY A 219
 None
GOL  A 301 (-3.0A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.7A)
GOL  A 301 (-3.5A)
 0.35A 4n9kA-4hesA:
28.5		 4n9kA-4hesA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		7 / 12 ALA A  55
SER A  56
SER A 117
ASN A 119
LYS A 217
THR A 218
GLY A 219
 None
GOL  A 301 (-3.0A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.7A)
GOL  A 301 (-3.5A)
 0.39A 4n9kB-4hesA:
28.1		 4n9kB-4hesA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 12 GLY A 260
ALA A 257
GLU A 268
LEU A 242
ILE A 231
 None
FMT  A 304 ( 4.0A)
None
None
None
 1.10A 4uw0A-4hesA:
undetectable		 4uw0A-4hesA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		4 / 6 LEU A  95
LEU A  83
SER A  84
VAL A 128
 None
 1.23A 5a6iA-4hesA:
undetectable		 5a6iA-4hesA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		6 / 12 ALA A  55
SER A  56
SER A 117
ASN A 119
LYS A 217
GLY A 219
 None
GOL  A 301 (-3.0A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.5A)
 0.31A 5ghyA-4hesA:
28.3		 5ghyA-4hesA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		6 / 12 ALA A  55
SER A  56
SER A 117
ASN A 119
LYS A 217
GLY A 219
 None
GOL  A 301 (-3.0A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.5A)
 0.31A 5ghyB-4hesA:
28.2		 5ghyB-4hesA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		7 / 11 ALA A  55
SER A  56
SER A 117
ASN A 119
LYS A 217
THR A 218
GLY A 219
 None
GOL  A 301 (-3.0A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.7A)
GOL  A 301 (-3.5A)
 0.37A 5ghzA-4hesA:
28.3		 5ghzA-4hesA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		7 / 10 ALA A  55
SER A  56
SER A 117
ASN A 119
LYS A 217
THR A 218
GLY A 219
 None
GOL  A 301 (-3.0A)
GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.7A)
GOL  A 301 (-3.5A)
 0.35A 5ghzB-4hesA:
28.4		 5ghzB-4hesA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		3 / 3 HIS A 215
GLU A 232
TRP A 192
 None
 1.23A 5odiD-4hesA:
undetectable		 5odiD-4hesA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		3 / 3 HIS A 215
GLU A 232
TRP A 192
 None
 1.20A 5odqD-4hesA:
undetectable		 5odqD-4hesA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		3 / 3 HIS A 215
GLU A 232
TRP A 192
 None
 1.16A 5odrD-4hesA:
undetectable		 5odrD-4hesA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 12 SER A  56
SER A 117
LYS A 217
THR A 218
GLY A 219
 GOL  A 301 (-3.0A)
GOL  A 301 (-2.7A)
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.7A)
GOL  A 301 (-3.5A)
 0.44A 6b6cA-4hesA:
27.4		 6b6cA-4hesA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 12 SER A  56
SER A 117
LYS A 217
THR A 218
GLY A 219
 GOL  A 301 (-3.0A)
GOL  A 301 (-2.7A)
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.7A)
GOL  A 301 (-3.5A)
 0.53A 6b6fA-4hesA:
27.5		 6b6fA-4hesA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		6 / 12 SER A 117
ASN A 119
LYS A 217
GLY A 219
SER A 220
ASN A 249
 GOL  A 301 (-2.7A)
None
GOL  A 301 ( 4.6A)
GOL  A 301 (-3.5A)
GOL  A 301 (-4.8A)
None
 0.85A 6c79A-4hesA:
29.5		 6c79A-4hesA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 12 VAL A 224
ASP A 222
ALA A  55
SER A  53
GLN A  96
 None
 1.19A 6ew0F-4hesA:
undetectable		 6ew0F-4hesA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 4hes BETA-LACTAMASE CLASS
A-LIKE PROTEIN
(Veillonella
parvula) 		5 / 12 VAL A 224
ASP A 222
ALA A  55
SER A  53
GLN A  96
 None
 1.20A 6ew0G-4hesA:
undetectable		 6ew0G-4hesA:
13.09