SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hf5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 4hf5 FAB 8F8 HEAVY CHAIN
(Homo
sapiens) 		4 / 7 TYR H 100
TYR H 100
HIS H 100
TYR H 100
 None
 1.11A 2ombC-4hf5H:
11.5
2ombD-4hf5H:
11.8		 2ombC-4hf5H:
31.95
2ombD-4hf5H:
31.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1161_1
(ALLERGEN ARG R 1)		 4hf5 FAB 8F8 HEAVY CHAIN
(Homo
sapiens) 		4 / 4 VAL H 100
TYR H 100
VAL H  33
SER H  55
 None
 1.32A 2x45B-4hf5H:
undetectable		 2x45B-4hf5H:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4hf5 FAB 8F8 HEAVY CHAIN
(Homo
sapiens) 		4 / 7 ALA H  88
THR H  87
VAL H 109
GLU H  85
 None
 0.83A 5ecoD-4hf5H:
undetectable		 5ecoD-4hf5H:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4hf5 FAB 8F8 HEAVY CHAIN
(Homo
sapiens) 		3 / 3 SER H  21
LEU H  82
MET H  82
 None
 0.86A 5ikrB-4hf5H:
undetectable		 5ikrB-4hf5H:
17.51