SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hf7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 4hf7 PUTATIVE
ACYLHYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A  90
VAL A 153
ILE A 134
ASP A 117
 None
 1.02A 2x45B-4hf7A:
undetectable		 2x45B-4hf7A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 4hf7 PUTATIVE
ACYLHYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A  90
VAL A 153
ILE A 134
ASP A 117
 None
 1.03A 2x45C-4hf7A:
undetectable		 2x45C-4hf7A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 4hf7 PUTATIVE
ACYLHYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A  90
VAL A 153
ILE A 134
ASP A 117
 None
 0.98A 3bu1A-4hf7A:
undetectable		 3bu1A-4hf7A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4hf7 PUTATIVE
ACYLHYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A  63
THR A 115
VAL A  68
PHE A  93
 OSE  A  62 ( 4.3A)
OSE  A  62 ( 4.4A)
None
None
 1.04A 4iarA-4hf7A:
undetectable		 4iarA-4hf7A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4hf7 PUTATIVE
ACYLHYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ASP A 222
TYR A 209
HIS A  71
THR A  70
 None
 1.35A 4paeA-4hf7A:
undetectable		 4paeA-4hf7A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 4hf7 PUTATIVE
ACYLHYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 11 PHE A 131
ILE A 179
ASN A 176
TYR A 182
TYR A 129
 None
 1.41A 4rtrA-4hf7A:
4.0		 4rtrA-4hf7A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4hf7 PUTATIVE
ACYLHYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 11 SER A  90
THR A 130
ALA A 156
THR A 122
GLY A 123
 None
 1.33A 4zjoD-4hf7A:
undetectable		 4zjoD-4hf7A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 4hf7 PUTATIVE
ACYLHYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 111
VAL A 110
GLY A  60
PHE A  58
LEU A 104
 None
 1.05A 5ergB-4hf7A:
undetectable		 5ergB-4hf7A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 4hf7 PUTATIVE
ACYLHYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A  97
ARG A  96
ARG A  83
ALA A 141
 None
 1.31A 6b89A-4hf7A:
undetectable		 6b89A-4hf7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 4hf7 PUTATIVE
ACYLHYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 PHE A  93
ARG A  96
GLN A  92
 None
 1.17A 6g1pB-4hf7A:
undetectable		 6g1pB-4hf7A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 4hf7 PUTATIVE
ACYLHYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A  78
ILE A 232
VAL A 110
ILE A 149
PRO A 216
 None
 1.17A 6hlpA-4hf7A:
4.5		 6hlpA-4hf7A:
15.11