SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hfq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI3_B_PE2B2_1
(THYMIDINE KINASE)		 4hfq MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 GLU A 125
ILE A  76
ILE A  82
TYR A 194
GLU A  78
 None
None
None
None
GOL  A 315 (-2.7A)
 1.46A 1ki3B-4hfqA:
undetectable		 1ki3B-4hfqA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4hfq MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 CYH A  83
ILE A  82
PRO A  96
ILE A 114
 None
None
SO4  A 304 ( 4.9A)
None
 0.97A 4w5oA-4hfqA:
undetectable		 4w5oA-4hfqA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4hfq MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 CYH A  83
ILE A  82
PRO A  96
ILE A 114
 None
None
SO4  A 304 ( 4.9A)
None
 0.99A 4z4eA-4hfqA:
undetectable		 4z4eA-4hfqA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4hfq MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 CYH A  83
ILE A  82
PRO A  96
ILE A 114
 None
None
SO4  A 304 ( 4.9A)
None
 0.99A 4z4gA-4hfqA:
undetectable		 4z4gA-4hfqA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4hfq MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 VAL A 147
ASN A 109
ILE A 110
GLU A 113
 None
 1.11A 6h7uA-4hfqA:
undetectable		 6h7uA-4hfqA:
17.81