SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hfu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		3 / 3 VAL H  20
VAL H  82
TRP H  36
 None
 0.80A 1av2C-4hfuH:
undetectable
1av2D-4hfuH:
undetectable		 1av2C-4hfuH:
8.85
1av2D-4hfuH:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 4hfu HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 7 LEU A 194
THR A 155
LEU A 251
GLY A 249
 None
 0.90A 1gtiB-4hfuA:
undetectable		 1gtiB-4hfuA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		4 / 8 SER H  30
ILE H  51
GLU H  98
GLY H  97
 None
 0.96A 1meiA-4hfuH:
undetectable		 1meiA-4hfuH:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		3 / 3 ASP H  65
PHE H  63
ASN H  82
 None
 0.72A 1sg9B-4hfuH:
undetectable		 1sg9B-4hfuH:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		3 / 3 VAL H  20
VAL H  82
TRP H  36
 None
 0.86A 1w5uC-4hfuH:
undetectable
1w5uD-4hfuH:
undetectable		 1w5uC-4hfuH:
8.85
1w5uD-4hfuH:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		3 / 3 ARG H  38
ARG H  62
ARG H  66
 None
 1.02A 2jb7A-4hfuH:
undetectable
2jb7B-4hfuH:
undetectable
2jb7C-4hfuH:
undetectable		 2jb7A-4hfuH:
19.91
2jb7B-4hfuH:
19.91
2jb7C-4hfuH:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		3 / 3 ARG H  66
ARG H  38
ARG H  62
 None
 1.01A 2jb7A-4hfuH:
undetectable
2jb7B-4hfuH:
undetectable
2jb7C-4hfuH:
undetectable		 2jb7A-4hfuH:
19.91
2jb7B-4hfuH:
19.91
2jb7C-4hfuH:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 4hfu FAB 8M2 HEAVY CHAIN
HEMAGGLUTININ HA1
(Homo
sapiens;
Influenza
A
virus) 		4 / 5 ILE H  53
SER H  31
PRO A 145
PHE H  29
 None
 1.40A 3bjwC-4hfuH:
undetectable		 3bjwC-4hfuH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		3 / 3 VAL H  20
VAL H  82
TRP H  36
 None
 0.92A 3l8lA-4hfuH:
undetectable
3l8lB-4hfuH:
undetectable		 3l8lA-4hfuH:
8.85
3l8lB-4hfuH:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		3 / 3 VAL H  20
VAL H  82
TRP H  36
 None
 0.92A 3l8lC-4hfuH:
undetectable
3l8lD-4hfuH:
undetectable		 3l8lC-4hfuH:
8.85
3l8lD-4hfuH:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 ASP H 101
VAL H  95
GLY H  97
TYR H 100
 None
 1.31A 3w9tA-4hfuH:
undetectable		 3w9tA-4hfuH:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 ASP H 101
VAL H  95
GLY H  97
TYR H 100
 None
 1.32A 3w9tB-4hfuH:
undetectable		 3w9tB-4hfuH:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 ASP H 101
VAL H  95
GLY H  97
TYR H 100
 None
 1.31A 3w9tC-4hfuH:
undetectable		 3w9tC-4hfuH:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 ASP H 101
VAL H  95
GLY H  97
TYR H 100
 None
 1.31A 3w9tD-4hfuH:
undetectable		 3w9tD-4hfuH:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 ASP H 101
VAL H  95
GLY H  97
TYR H 100
 None
 1.31A 3w9tE-4hfuH:
undetectable		 3w9tE-4hfuH:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 ASP H 101
VAL H  95
GLY H  97
TYR H 100
 None
 1.31A 3w9tF-4hfuH:
undetectable		 3w9tF-4hfuH:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 ASP H 101
VAL H  95
GLY H  97
TYR H 100
 None
 1.31A 3w9tG-4hfuH:
undetectable		 3w9tG-4hfuH:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4hfu HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 7 ILE A 179
HIS A 184
VAL A 223
PHE A 148
 None
 1.11A 4a97H-4hfuA:
undetectable		 4a97H-4hfuA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4hfu HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.87A 4eq4A-4hfuA:
undetectable		 4eq4A-4hfuA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4hfu HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.89A 4eqlA-4hfuA:
undetectable		 4eqlA-4hfuA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4hfu HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.89A 4eqlB-4hfuA:
undetectable		 4eqlB-4hfuA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4hfu HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 6 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.96A 4l39A-4hfuA:
undetectable		 4l39A-4hfuA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4hfu HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.94A 4l39B-4hfuA:
undetectable		 4l39B-4hfuA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4hfu HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 8 GLU A  60
GLU A 275
ILE A  56
LEU A  53
 None
 0.95A 4mj8A-4hfuA:
undetectable		 4mj8A-4hfuA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 4hfu HEMAGGLUTININ HA1
(Influenza
A
virus) 		5 / 12 ILE A  66
TRP A  84
LEU A 108
LEU A 111
PHE A 116
 None
 1.42A 4pbhA-4hfuA:
undetectable		 4pbhA-4hfuA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.95A 4qvnH-4hfuH:
undetectable
4qvnI-4hfuH:
undetectable		 4qvnH-4hfuH:
20.00
4qvnI-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 10 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.95A 4qvnV-4hfuH:
undetectable
4qvnW-4hfuH:
undetectable		 4qvnV-4hfuH:
20.00
4qvnW-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.93A 4qvpH-4hfuH:
undetectable
4qvpI-4hfuH:
undetectable		 4qvpH-4hfuH:
20.00
4qvpI-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.93A 4qvpV-4hfuH:
undetectable
4qvpW-4hfuH:
undetectable		 4qvpV-4hfuH:
20.00
4qvpW-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.95A 4qvqH-4hfuH:
undetectable
4qvqI-4hfuH:
undetectable		 4qvqH-4hfuH:
20.00
4qvqI-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.94A 4qvqV-4hfuH:
undetectable
4qvqW-4hfuH:
undetectable		 4qvqV-4hfuH:
20.00
4qvqW-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.95A 4qvvH-4hfuH:
undetectable		 4qvvH-4hfuH:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.95A 4qvvV-4hfuH:
undetectable		 4qvvV-4hfuH:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.93A 4qvyH-4hfuH:
undetectable		 4qvyH-4hfuH:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.93A 4qvyV-4hfuH:
undetectable
4qvyW-4hfuH:
undetectable		 4qvyV-4hfuH:
20.00
4qvyW-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.93A 4qw0H-4hfuH:
undetectable
4qw0I-4hfuH:
undetectable		 4qw0H-4hfuH:
20.00
4qw0I-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.93A 4qw0V-4hfuH:
undetectable
4qw0W-4hfuH:
undetectable		 4qw0V-4hfuH:
20.00
4qw0W-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.96A 4qw1H-4hfuH:
undetectable
4qw1I-4hfuH:
undetectable		 4qw1H-4hfuH:
20.00
4qw1I-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.96A 4qw1V-4hfuH:
undetectable
4qw1W-4hfuH:
undetectable		 4qw1V-4hfuH:
20.00
4qw1W-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 4hfu HEMAGGLUTININ HA1
(Influenza
A
virus) 		5 / 12 LEU A 177
LEU A 108
SER A  65
LEU A  71
ILE A 179
 None
 1.05A 4x1fA-4hfuA:
undetectable		 4x1fA-4hfuA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.94A 5bxnH-4hfuH:
undetectable
5bxnI-4hfuH:
undetectable		 5bxnH-4hfuH:
22.52
5bxnI-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.95A 5cz7V-4hfuH:
undetectable
5cz7W-4hfuH:
undetectable		 5cz7V-4hfuH:
20.00
5cz7W-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.93A 5d0xV-4hfuH:
undetectable		 5d0xV-4hfuH:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 4hfu HEMAGGLUTININ HA1
FAB 8M2 HEAVY CHAIN
(Influenza
A
virus;
Homo
sapiens) 		6 / 10 GLY A 225
GLY A 227
SER A 228
LEU A 226
GLU A 190
TYR H 100
 None
 1.15A 5hwkA-4hfuA:
undetectable		 5hwkA-4hfuA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 4hfu HEMAGGLUTININ HA1
FAB 8M2 HEAVY CHAIN
(Influenza
A
virus;
Homo
sapiens) 		6 / 10 GLY A 225
GLY A 227
SER A 228
LEU A 226
GLU A 190
TYR H 100
 None
 1.15A 5hwkB-4hfuA:
undetectable		 5hwkB-4hfuA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4hfu HEMAGGLUTININ HA1
(Influenza
A
virus) 		3 / 3 VAL A 202
SER A 203
TRP A 180
 None
 1.06A 5jwaA-4hfuA:
undetectable		 5jwaA-4hfuA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.91A 5l5fH-4hfuH:
undetectable
5l5fI-4hfuH:
undetectable		 5l5fH-4hfuH:
20.00
5l5fI-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 0.91A 5l5fV-4hfuH:
undetectable
5l5fW-4hfuH:
undetectable		 5l5fV-4hfuH:
20.00
5l5fW-4hfuH:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 1.04A 6hwdH-4hfuH:
undetectable
6hwdI-4hfuH:
undetectable		 6hwdH-4hfuH:
20.93
6hwdI-4hfuH:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
 None
 1.04A 6hwdV-4hfuH:
undetectable		 6hwdV-4hfuH:
20.93