SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hfw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 4hfw 6-26 FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 4 HIS H  35
ALA H  97
PHE H 109
GLY H  99
 None
 1.24A 1mj2B-4hfwH:
undetectable		 1mj2B-4hfwH:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 4hfw 6-26 FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 4 HIS H  35
ALA H  97
PHE H 109
GLY H  99
 None
 1.27A 1mj2D-4hfwH:
undetectable		 1mj2D-4hfwH:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)		 4hfw 6-26 FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 4 HIS H  35
ALA H  97
PHE H 109
GLY H  99
 None
 1.27A 1mjoB-4hfwH:
undetectable		 1mjoB-4hfwH:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 4hfw 6-26 FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 4 HIS H  35
ALA H  97
PHE H 109
GLY H  99
 None
 1.21A 1mjoA-4hfwH:
undetectable		 1mjoA-4hfwH:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)		 4hfw 6-26 FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 4 HIS H  35
ALA H  97
PHE H 109
GLY H  99
 None
 1.25A 1mjoD-4hfwH:
undetectable		 1mjoD-4hfwH:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4hfw 6-26 FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 6 LEU H 196
GLY H 197
ALA H 132
PRO H 133
 None
 0.34A 3huoA-4hfwH:
undetectable		 3huoA-4hfwH:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4hfw 6-26 FAB HEAVY CHAIN
(Homo
sapiens) 		3 / 3 GLN H   3
GLU H   1
LYS H   1
 None
 1.20A 3su9A-4hfwH:
undetectable		 3su9A-4hfwH:
21.13