SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hfx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 4hfx TRANSCRIPTION
ELONGATION FACTOR B
POLYPEPTIDE 3
(Homo
sapiens) 		4 / 8 TYR A  64
THR A  19
PRO A  20
TYR A  24
 None
 0.95A 1z2bB-4hfxA:
undetectable		 1z2bB-4hfxA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4hfx TRANSCRIPTION
ELONGATION FACTOR B
POLYPEPTIDE 3
(Homo
sapiens) 		4 / 7 ASP A  38
LEU A  23
GLN A  68
LEU A  65
 None
 1.13A 4ib4A-4hfxA:
undetectable		 4ib4A-4hfxA:
12.04