SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hga'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 4hga HISTONE H3.3
(Homo
sapiens) 		3 / 3 ARG B 128
ASP B 106
ARG B 134
 None
 0.48A 4wq4B-4hgaB:
undetectable		 4wq4B-4hgaB:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4hga HISTONE H3.3
(Homo
sapiens) 		4 / 5 GLY B 132
ASP B 106
ARG B 128
ARG B 134
 None
 1.39A 6dwdB-4hgaB:
undetectable
6dwdD-4hgaB:
undetectable		 6dwdB-4hgaB:
13.04
6dwdD-4hgaB:
13.04