SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hgk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A4G_A_ZMRA466_1 (NEURAMINIDASE)	4hgk	SHARK V-NAR ANTIBODY (Squalus acanthias)	5 / 12	ARG C 73 GLU C 66 ARG C 57 ASN C 59 TYR C 74	None	1.39A	1a4gA-4hgkC: undetectable	1a4gA-4hgkC: 15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QKN_A_RALA600_1 (ESTROGEN RECEPTOR BETA)	4hgk	SHARK V-NAR ANTIBODY (Squalus acanthias)	5 / 12	LEU C 87 THR C 38 LEU C 119 ILE C 101 GLY C 116	None	0.98A	1qknA-4hgkC: undetectable	1qknA-4hgkC: 15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B7Q_A_ZMRA601_1 (NEURAMINIDASE)	4hgk	SHARK V-NAR ANTIBODY (Squalus acanthias)	5 / 12	ARG C 73 GLU C 66 ARG C 57 ASN C 59 TYR C 74	None	1.46A	4b7qA-4hgkC: undetectable	4b7qA-4hgkC: 15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B7Q_C_ZMRC601_1 (NEURAMINIDASE)	4hgk	SHARK V-NAR ANTIBODY (Squalus acanthias)	5 / 12	ARG C 73 GLU C 66 ARG C 57 ASN C 59 TYR C 74	None	1.36A	4b7qC-4hgkC: undetectable	4b7qC-4hgkC: 15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B7Q_D_ZMRD601_1 (NEURAMINIDASE)	4hgk	SHARK V-NAR ANTIBODY (Squalus acanthias)	5 / 12	ARG C 73 GLU C 66 ARG C 57 ASN C 59 TYR C 74	None	1.48A	4b7qD-4hgkC: undetectable	4b7qD-4hgkC: 15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ODH_G_ACTG710_0 (HETERODISULFIDE REDUCTASE, SUBUNIT A)	4hgk	SHARK V-NAR ANTIBODY (Squalus acanthias)	4 / 4	ARG C 73 ILE C 89 TYR C 100 ILE C 68	None	1.34A	5odhG-4hgkC: undetectable	5odhG-4hgkC: 10.55

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A4G_A_ZMRA466_1","NEURAMINIDASE","4hgk","SHARK V-NAR ANTIBODY","Squalus acanthias",5,"ARG C  73;GLU C  66;ARG C  57;ASN C  59;TYR C  74","None","1.39A","1a4gA-4hgkC:undetectable","1a4gA-4hgkC:15.90"],["1QKN_A_RALA600_1","ESTROGEN RECEPTOR BETA","4hgk","SHARK V-NAR ANTIBODY","Squalus acanthias",5,"LEU C  87;THR C  38;LEU C 119;ILE C 101;GLY C 116","None","0.98A","1qknA-4hgkC:undetectable","1qknA-4hgkC:15.54"],["4B7Q_A_ZMRA601_1","NEURAMINIDASE","4hgk","SHARK V-NAR ANTIBODY","Squalus acanthias",5,"ARG C  73;GLU C  66;ARG C  57;ASN C  59;TYR C  74","None","1.46A","4b7qA-4hgkC:undetectable","4b7qA-4hgkC:15.14"],["4B7Q_C_ZMRC601_1","NEURAMINIDASE","4hgk","SHARK V-NAR ANTIBODY","Squalus acanthias",5,"ARG C  73;GLU C  66;ARG C  57;ASN C  59;TYR C  74","None","1.36A","4b7qC-4hgkC:undetectable","4b7qC-4hgkC:15.14"],["4B7Q_D_ZMRD601_1","NEURAMINIDASE","4hgk","SHARK V-NAR ANTIBODY","Squalus acanthias",5,"ARG C  73;GLU C  66;ARG C  57;ASN C  59;TYR C  74","None","1.48A","4b7qD-4hgkC:undetectable","4b7qD-4hgkC:15.14"],["5ODH_G_ACTG710_0","HETERODISULFIDE REDUCTASE, SUBUNIT A","4hgk","SHARK V-NAR ANTIBODY","Squalus acanthias",4,"ARG C  73;ILE C  89;TYR C 100;ILE C  68","None","1.34A","5odhG-4hgkC:undetectable","5odhG-4hgkC:10.55"]]