SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hh5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4hh5 PUTATIVE TYPE VI
SECRETION PROTEIN
(Escherichia
coli) 		5 / 12 GLY A  75
HIS A  35
LEU A 134
HIS A  42
LEU A  29
 None
 1.33A 1fm6D-4hh5A:
undetectable		 1fm6D-4hh5A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 4hh5 PUTATIVE TYPE VI
SECRETION PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 138
LEU A 119
ILE A 113
LEU A  97
PRO A 126
 None
 1.10A 2qxsB-4hh5A:
undetectable		 2qxsB-4hh5A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 4hh5 PUTATIVE TYPE VI
SECRETION PROTEIN
(Escherichia
coli) 		5 / 12 GLY A  53
GLY A  51
VAL A 116
HIS A 117
SER A 156
 BR  A 201 (-3.4A)
BR  A 201 ( 4.2A)
None
None
None
 1.21A 3dlcA-4hh5A:
undetectable		 3dlcA-4hh5A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 4hh5 PUTATIVE TYPE VI
SECRETION PROTEIN
(Escherichia
coli) 		4 / 5 HIS A  42
CYH A  30
ILE A  38
LEU A  29
 None
 1.40A 3qpkA-4hh5A:
undetectable		 3qpkA-4hh5A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4hh5 PUTATIVE TYPE VI
SECRETION PROTEIN
(Escherichia
coli) 		5 / 12 VAL A 104
LEU A  47
ASP A  54
ALA A 121
LEU A  98
 None
 1.02A 6b0iB-4hh5A:
undetectable		 6b0iB-4hh5A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 4hh5 PUTATIVE TYPE VI
SECRETION PROTEIN
(Escherichia
coli) 		5 / 7 LEU A  55
VAL A 129
LEU A  44
LEU A  73
LEU A 138
 BR  A 201 ( 4.4A)
None
None
None
None
 1.04A 6g9bA-4hh5A:
undetectable
6g9bB-4hh5A:
undetectable		 6g9bA-4hh5A:
17.90
6g9bB-4hh5A:
20.90