SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hhr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 11 THR A 583
THR A 310
LEU A 290
VAL A 286
VAL A 313
 None
 1.27A 1akdA-4hhrA:
undetectable		 1akdA-4hhrA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 11 LEU A 540
ALA A 542
LEU A 453
ILE A 484
LEU A 534
 None
 1.15A 1g50A-4hhrA:
undetectable		 1g50A-4hhrA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 7 ASP A  99
LEU A  71
SER A 377
SER A 110
 None
 1.16A 1ig3A-4hhrA:
undetectable
1ig3B-4hhrA:
undetectable		 1ig3A-4hhrA:
19.66
1ig3B-4hhrA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWJ_A_CAMA418_0
(CYTOCHROME P450-CAM)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 9 THR A 583
THR A 310
LEU A 290
VAL A 286
VAL A 313
 None
 1.16A 1iwjA-4hhrA:
undetectable		 1iwjA-4hhrA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 9 GLY A 470
GLU A 428
GLY A 424
GLY A 258
ASP A 255
 None
 1.22A 1mxdA-4hhrA:
undetectable		 1mxdA-4hhrA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 4 HIS A 163
ASP A 220
SER A 107
ASP A 264
 IMD  A 702 (-3.7A)
CA  A 703 (-2.9A)
None
None
 1.45A 1n2xA-4hhrA:
undetectable		 1n2xA-4hhrA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 10 THR A 583
THR A 310
LEU A 290
VAL A 286
VAL A 313
 None
 1.23A 1o76A-4hhrA:
undetectable		 1o76A-4hhrA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 540
ALA A 542
LEU A 453
ILE A 484
LEU A 534
 None
 1.23A 1pcgA-4hhrA:
undetectable		 1pcgA-4hhrA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 10 VAL A  41
LEU A 560
TYR A 557
VAL A  61
LEU A  50
 None
None
None
BNG  A 714 ( 4.8A)
BNG  A 714 ( 4.9A)
 1.14A 1pxxA-4hhrA:
8.4		 1pxxA-4hhrA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RR8_A_TTCA100_1
(DNA TOPOISOMERASE I)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 5 GLU A 533
ARG A 500
LYS A  18
ASP A  19
 None
 1.35A 1rr8C-4hhrA:
undetectable		 1rr8C-4hhrA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RRJ_B_TTCB990_1
(DNA TOPOISOMERASE I)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 5 GLU A 533
ARG A 500
LYS A  18
ASP A  19
 None
 1.37A 1rrjA-4hhrA:
0.0		 1rrjA-4hhrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 9 THR A 583
THR A 310
LEU A 290
VAL A 286
VAL A 313
 None
 1.20A 1t86B-4hhrA:
undetectable		 1t86B-4hhrA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 11 GLY A 435
ILE A 245
LEU A 252
ALA A 274
ALA A 277
 None
 0.97A 1x7pA-4hhrA:
undetectable
1x7pB-4hhrA:
undetectable		 1x7pA-4hhrA:
17.99
1x7pB-4hhrA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE509_0
(NAD-DEPENDENT
DEACETYLASE 2)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 6 ASP A 171
GLU A 489
TYR A 485
LYS A 196
 None
 1.44A 1yc2A-4hhrA:
undetectable
1yc2B-4hhrA:
undetectable
1yc2E-4hhrA:
undetectable		 1yc2A-4hhrA:
17.05
1yc2B-4hhrA:
17.05
1yc2E-4hhrA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 11 THR A 583
THR A 310
LEU A 290
VAL A 286
VAL A 313
 None
 1.22A 2a1nA-4hhrA:
undetectable		 2a1nA-4hhrA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 4 ILE A 507
ASP A 535
LEU A 540
ARG A 500
 P6G  A 715 (-4.8A)
None
None
None
 1.26A 2a7qA-4hhrA:
undetectable		 2a7qA-4hhrA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 10 THR A 583
THR A 310
LEU A 290
VAL A 286
VAL A 313
 None
 1.29A 2cp4A-4hhrA:
undetectable		 2cp4A-4hhrA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIV_A_T3A933_1
(ANDROGEN RECEPTOR)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 9 PRO A 506
ILE A 507
GLY A 529
GLU A 532
ARG A 500
 None
P6G  A 715 (-4.8A)
None
None
None
 1.36A 2pivA-4hhrA:
undetectable		 2pivA-4hhrA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 5 PHE A 556
PHE A 549
TRP A  47
GLY A 335
 None
 1.41A 2qmzA-4hhrA:
undetectable
2qmzB-4hhrA:
undetectable		 2qmzA-4hhrA:
16.41
2qmzB-4hhrA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 TRP A 621
GLN A 325
TRP A 269
 None
None
HEM  A 701 (-4.8A)
 1.30A 2vqyA-4hhrA:
undetectable		 2vqyA-4hhrA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 12 ASP A 264
THR A 231
VAL A 235
ILE A 261
GLN A 276
 None
CL  A 713 ( 4.5A)
None
None
None
 1.10A 2yzqA-4hhrA:
undetectable		 2yzqA-4hhrA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 8 ILE A 320
ASN A 339
ARG A 566
TYR A 341
 None
None
CL  A 711 (-3.3A)
None
 1.05A 2zw9B-4hhrA:
undetectable		 2zw9B-4hhrA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 9 THR A 583
THR A 310
LEU A 290
VAL A 286
VAL A 313
 None
 1.22A 3cppA-4hhrA:
undetectable		 3cppA-4hhrA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 7 TYR A  58
VAL A 363
ILE A 359
ARG A 565
 None
 1.20A 3ik3B-4hhrA:
undetectable		 3ik3B-4hhrA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 GLU A 170
ASP A 167
ASP A 467
 None
 0.73A 3jb2A-4hhrA:
undetectable		 3jb2A-4hhrA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 11 PHE A 160
VAL A 314
ILE A 317
ILE A 600
PHE A 618
 None
 1.38A 3o5rA-4hhrA:
undetectable		 3o5rA-4hhrA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 5 PHE A 549
LEU A  59
GLY A 335
VAL A 324
 None
 1.00A 3wrkD-4hhrA:
undetectable		 3wrkD-4hhrA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 5 VAL A 477
LEU A 482
LEU A 479
ASN A 267
 None
HEM  A 701 (-4.5A)
HEM  A 701 (-4.5A)
HEM  A 701 ( 3.4A)
 0.93A 4a9jA-4hhrA:
2.8		 4a9jA-4hhrA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 5 VAL A 477
LEU A 482
LEU A 479
ASN A 267
 None
HEM  A 701 (-4.5A)
HEM  A 701 (-4.5A)
HEM  A 701 ( 3.4A)
 0.85A 4a9jB-4hhrA:
2.8		 4a9jB-4hhrA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 5 VAL A 477
LEU A 482
LEU A 479
ASN A 267
 None
HEM  A 701 (-4.5A)
HEM  A 701 (-4.5A)
HEM  A 701 ( 3.4A)
 0.88A 4a9jC-4hhrA:
2.7		 4a9jC-4hhrA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 9 THR A 583
THR A 310
LEU A 290
VAL A 286
VAL A 313
 None
 1.14A 4ek1B-4hhrA:
undetectable		 4ek1B-4hhrA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 8 SER A 268
ASN A 267
GLY A 470
GLY A 427
 None
HEM  A 701 ( 3.4A)
None
None
 0.87A 4fo4B-4hhrA:
undetectable		 4fo4B-4hhrA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 11 PHE A 112
SER A 110
GLY A 113
ILE A 551
LEU A 451
 None
 1.07A 4kt0A-4hhrA:
undetectable
4kt0J-4hhrA:
undetectable		 4kt0A-4hhrA:
20.82
4kt0J-4hhrA:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 8 THR A 583
THR A 310
LEU A 290
VAL A 286
 None
 1.14A 4l4dA-4hhrA:
undetectable		 4l4dA-4hhrA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 ASP A 576
VAL A 309
ASN A  98
 None
 0.57A 4lmnA-4hhrA:
undetectable		 4lmnA-4hhrA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 587
GLY A 586
LEU A 290
HIS A 283
THR A 310
 None
 1.45A 4okxA-4hhrA:
undetectable		 4okxA-4hhrA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 12 GLU A 533
LEU A 137
GLU A 497
GLY A 539
ALA A 542
 None
 1.25A 4xe5A-4hhrA:
2.7		 4xe5A-4hhrA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 12 ALA A 569
ASP A 570
GLU A 568
LEU A  71
PRO A 100
 None
 1.21A 4xi3A-4hhrA:
undetectable		 4xi3A-4hhrA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 6 ARG A  91
ARG A 566
VAL A 223
ASP A 164
 None
CL  A 711 (-3.3A)
None
CA  A 703 (-3.3A)
 1.28A 4xqeB-4hhrA:
undetectable		 4xqeB-4hhrA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 5 GLY A 226
PRO A 468
THR A 231
THR A 216
 None
None
CL  A 713 ( 4.5A)
CA  A 703 (-3.6A)
 1.20A 5h5fA-4hhrA:
undetectable		 5h5fA-4hhrA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 4 LEU A 439
LEU A 422
GLY A 427
GLU A 428
 None
 1.22A 5hhjA-4hhrA:
undetectable		 5hhjA-4hhrA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 12 VAL A  41
LEU A 560
TYR A 557
VAL A  61
LEU A  50
 None
None
None
BNG  A 714 ( 4.8A)
BNG  A 714 ( 4.9A)
 1.11A 5ikqA-4hhrA:
29.7		 5ikqA-4hhrA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 12 VAL A  41
LEU A 560
TYR A 557
VAL A  61
LEU A  50
 None
None
None
BNG  A 714 ( 4.8A)
BNG  A 714 ( 4.9A)
 1.13A 5ikqB-4hhrA:
17.0		 5ikqB-4hhrA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 11 ILE A 558
ARG A 566
ALA A 563
VAL A 492
LEU A 540
 None
CL  A 711 (-3.3A)
CL  A 711 ( 4.0A)
None
None
 1.13A 5ji0A-4hhrA:
undetectable		 5ji0A-4hhrA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 VAL A 599
HIS A 283
VAL A 286
 None
 0.44A 5jmnC-4hhrA:
undetectable		 5jmnC-4hhrA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 LYS A 242
ASP A 299
ILE A 224
 None
 0.90A 5kc4E-4hhrA:
undetectable		 5kc4E-4hhrA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 10 PHE A 112
SER A 110
GLY A 113
ILE A 551
LEU A 451
 None
 1.17A 5oy01-4hhrA:
undetectable
5oy07-4hhrA:
undetectable		 5oy01-4hhrA:
7.50
5oy07-4hhrA:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 5 ASN A 578
ASP A 576
SER A 575
ARG A 571
 None
 1.43A 5w4zA-4hhrA:
undetectable		 5w4zA-4hhrA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 414
GLN A 415
ILE A 401
THR A 437
 None
 0.89A 6cduF-4hhrA:
2.4
6cduG-4hhrA:
undetectable		 6cduF-4hhrA:
18.79
6cduG-4hhrA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 8 ILE A 414
GLN A 415
ILE A 401
THR A 437
 None
 0.76A 6cduG-4hhrA:
undetectable
6cduH-4hhrA:
undetectable		 6cduG-4hhrA:
18.79
6cduH-4hhrA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 TYR A 527
ALA A 542
LEU A 137
 None
 0.73A 6d9kF-4hhrA:
undetectable		 6d9kF-4hhrA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 6 GLU A 170
ARG A 266
VAL A 477
PRO A 465
 None
 1.28A 6fgdA-4hhrA:
undetectable		 6fgdA-4hhrA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 12 PHE A 160
VAL A 314
ILE A 317
PHE A 618
ILE A 245
 None
 1.03A 6mkeA-4hhrA:
undetectable
6mkeD-4hhrA:
undetectable		 6mkeA-4hhrA:
9.62
6mkeD-4hhrA:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 12 PHE A 160
VAL A 314
ILE A 317
PHE A 618
ILE A 245
 None
 1.05A 6mkeB-4hhrA:
undetectable
6mkeC-4hhrA:
undetectable		 6mkeB-4hhrA:
9.62
6mkeC-4hhrA:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 4hhr ALPHA-DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 ILE A 581
THR A 580
PRO A  89
 None
 0.57A 6ncsA-4hhrA:
undetectable		 6ncsA-4hhrA:
19.51