SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hi2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4hi2 ACYLPHOSPHATASE
(Vibrio
cholerae) 		4 / 6 GLY A  12
VAL A  17
ALA A  69
SER A  70
 None
 1.02A 1p6kA-4hi2A:
undetectable		 1p6kA-4hi2A:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4hi2 ACYLPHOSPHATASE
(Vibrio
cholerae) 		5 / 12 TYR A  59
LEU A  60
VAL A  71
ALA A  36
VAL A  74
 None
 1.41A 2g70A-4hi2A:
undetectable		 2g70A-4hi2A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4hi2 ACYLPHOSPHATASE
(Vibrio
cholerae) 		4 / 8 LEU A  58
LEU A  28
TYR A  35
GLN A  15
 None
 1.19A 5hbsA-4hi2A:
undetectable		 5hbsA-4hi2A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 4hi2 ACYLPHOSPHATASE
(Vibrio
cholerae) 		3 / 3 LEU A  55
LEU A  58
TRP A  61
 None
 0.90A 5nwuA-4hi2A:
undetectable		 5nwuA-4hi2A:
23.53