SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hjc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		4 / 5 ALA A 914
GLN A 983
ILE A 915
ARG A 985
 None
 1.41A 2z0aA-4hjcA:
undetectable		 2z0aA-4hjcA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		5 / 10 PHE A 866
GLY A 868
ASP A 867
VAL A1020
LEU A 745
 None
 0.93A 3ay0B-4hjcA:
undetectable		 3ay0B-4hjcA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		4 / 8 ILE A 695
ALA A 719
PHE A1015
THR A1012
 None
 0.78A 3hrdA-4hjcA:
undetectable
3hrdB-4hjcA:
undetectable		 3hrdA-4hjcA:
20.55
3hrdB-4hjcA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		4 / 8 LYS A 813
ASN A 812
HIS A 836
ILE A 954
 None
 1.31A 3kp6A-4hjcA:
undetectable
3kp6B-4hjcA:
undetectable		 3kp6A-4hjcA:
14.75
3kp6B-4hjcA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		4 / 8 GLY A 886
ILE A 863
ASP A 867
SER A 869
 None
 0.73A 3pwwA-4hjcA:
undetectable		 3pwwA-4hjcA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		5 / 11 LEU A 734
PHE A 866
ASP A 867
THR A 864
ILE A 863
 None
 1.18A 4uuuA-4hjcA:
undetectable
4uuuB-4hjcA:
undetectable		 4uuuA-4hjcA:
14.72
4uuuB-4hjcA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		3 / 3 ARG A 848
TYR A 913
GLU A 907
 None
 0.71A 4zzbE-4hjcA:
2.8		 4zzbE-4hjcA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		4 / 4 VAL A1093
GLU A1092
GLY A1112
LEU A1114
 None
 1.39A 5g5gC-4hjcA:
undetectable		 5g5gC-4hjcA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		3 / 3 VAL A 916
ARG A 949
PRO A 924
 None
 0.49A 5koxA-4hjcA:
undetectable		 5koxA-4hjcA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		3 / 3 LYS A 988
ASN A 986
SER A 898
 None
 1.29A 5yw0A-4hjcA:
undetectable		 5yw0A-4hjcA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		3 / 3 SER A1075
SER A1054
ALA A1025
 None
 0.67A 6dwnC-4hjcA:
undetectable		 6dwnC-4hjcA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		4 / 5 LEU A 839
ARG A 933
PRO A 924
ARG A 925
 None
 1.27A 6ew0B-4hjcA:
undetectable		 6ew0B-4hjcA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		4 / 5 LEU A 839
ARG A 933
PRO A 924
ARG A 925
 None
 1.27A 6ew0D-4hjcA:
undetectable		 6ew0D-4hjcA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		4 / 5 LEU A 839
ARG A 933
PRO A 924
ARG A 925
 None
 1.27A 6ew0H-4hjcA:
undetectable		 6ew0H-4hjcA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		4 / 5 LEU A 839
ARG A 933
PRO A 924
ARG A 925
 None
 1.27A 6ew0I-4hjcA:
undetectable		 6ew0I-4hjcA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 4hjc ENVELOPE
GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus) 		3 / 3 ARG A 933
GLY A 930
GLU A 931
 None
 0.47A 6fgdA-4hjcA:
undetectable		 6fgdA-4hjcA:
20.59