SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hjf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 4hjf GGDEF FAMILY PROTEIN
(Caulobacter
vibrioides) 		5 / 11 GLY A 522
LEU A 314
GLY A 504
MET A 476
HIS A 512
 None
None
C2E  A 603 (-3.4A)
None
None
 1.44A 1iolA-4hjfA:
undetectable		 1iolA-4hjfA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 4hjf GGDEF FAMILY PROTEIN
(Caulobacter
vibrioides) 		3 / 3 PHE A 308
TRP A 369
GLU A 537
 None
 1.06A 1mogA-4hjfA:
undetectable		 1mogA-4hjfA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 4hjf GGDEF FAMILY PROTEIN
(Caulobacter
vibrioides) 		5 / 12 ALA A 441
GLY A 411
ALA A 412
LEU A 433
LEU A 436
 None
 1.02A 2nyuA-4hjfA:
undetectable		 2nyuA-4hjfA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4hjf GGDEF FAMILY PROTEIN
(Caulobacter
vibrioides) 		5 / 12 ALA A 439
LEU A 443
LEU A 415
VAL A 417
ILE A 390
 None
 1.12A 3adsB-4hjfA:
undetectable		 3adsB-4hjfA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 4hjf GGDEF FAMILY PROTEIN
(Caulobacter
vibrioides) 		5 / 12 LEU A 325
ARG A 470
GLU A 323
ALA A 528
ASP A 446
 C2E  A 603 (-3.5A)
C2E  A 603 (-4.1A)
CA  A 601 ( 2.7A)
None
CA  A 602 (-2.7A)
 1.14A 4aqlA-4hjfA:
7.0		 4aqlA-4hjfA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 4hjf GGDEF FAMILY PROTEIN
(Caulobacter
vibrioides) 		4 / 6 ASP A 447
ASP A 469
ALA A 502
ASP A 446
 CA  A 602 (-3.3A)
CA  A 602 (-3.6A)
None
CA  A 602 (-2.7A)
 1.13A 4mdaA-4hjfA:
undetectable		 4mdaA-4hjfA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 4hjf GGDEF FAMILY PROTEIN
(Caulobacter
vibrioides) 		4 / 6 ASP A 447
ASP A 469
ALA A 502
ASP A 446
 CA  A 602 (-3.3A)
CA  A 602 (-3.6A)
None
CA  A 602 (-2.7A)
 1.14A 4mdbA-4hjfA:
undetectable		 4mdbA-4hjfA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 4hjf GGDEF FAMILY PROTEIN
(Caulobacter
vibrioides) 		3 / 3 THR A 402
ALA A 363
ASN A 406
 None
 0.58A 5ersA-4hjfA:
undetectable		 5ersA-4hjfA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4hjf GGDEF FAMILY PROTEIN
(Caulobacter
vibrioides) 		4 / 4 LEU A 379
TYR A 307
PRO A 310
ILE A 311
 None
 1.40A 5esgA-4hjfA:
undetectable		 5esgA-4hjfA:
21.45