SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hkj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_B_SAMB302_0 (YCGJ)	4hkj	CPXV203 PROTEIN (Cowpox virus)	6 / 12	GLY D 51 GLY D 49 THR D 79 ALA D 24 ARG D 53 PHE D 27	None	1.35A	2gluB-4hkjD: undetectable	2gluB-4hkjD: 19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_A_PCFA1803_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	4hkj	CPXV203 PROTEIN (Cowpox virus)	5 / 10	TYR D 135 ILE D 105 ILE D 103 LEU D 129 HIS D 142	None	1.37A	5vkqA-4hkjD: undetectable 5vkqD-4hkjD: undetectable	5vkqA-4hkjD: 8.52 5vkqD-4hkjD: 8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_B_PCFB1808_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	4hkj	CPXV203 PROTEIN (Cowpox virus)	5 / 10	HIS D 142 TYR D 135 ILE D 105 ILE D 103 LEU D 129	None	1.34A	5vkqA-4hkjD: undetectable 5vkqB-4hkjD: undetectable	5vkqA-4hkjD: 8.52 5vkqB-4hkjD: 8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_D_PCFD1801_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	4hkj	CPXV203 PROTEIN (Cowpox virus)	5 / 10	HIS D 142 TYR D 135 ILE D 105 ILE D 103 LEU D 129	None	1.33A	5vkqC-4hkjD: undetectable 5vkqD-4hkjD: undetectable	5vkqC-4hkjD: 8.52 5vkqD-4hkjD: 8.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2GLU_B_SAMB302_0","YCGJ","4hkj","CPXV203 PROTEIN","Cowpox virus",6,"GLY D  51;GLY D  49;THR D  79;ALA D  24;ARG D  53;PHE D  27","None","1.35A","2gluB-4hkjD:undetectable","2gluB-4hkjD:19.60"],["5VKQ_A_PCFA1803_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","4hkj","CPXV203 PROTEIN","Cowpox virus",5,"TYR D 135;ILE D 105;ILE D 103;LEU D 129;HIS D 142","None","1.37A","5vkqA-4hkjD:undetectable;5vkqD-4hkjD:undetectable","5vkqA-4hkjD:8.52;5vkqD-4hkjD:8.52"],["5VKQ_B_PCFB1808_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","4hkj","CPXV203 PROTEIN","Cowpox virus",5,"HIS D 142;TYR D 135;ILE D 105;ILE D 103;LEU D 129","None","1.34A","5vkqA-4hkjD:undetectable;5vkqB-4hkjD:undetectable","5vkqA-4hkjD:8.52;5vkqB-4hkjD:8.52"],["5VKQ_D_PCFD1801_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","4hkj","CPXV203 PROTEIN","Cowpox virus",5,"HIS D 142;TYR D 135;ILE D 105;ILE D 103;LEU D 129","None","1.33A","5vkqC-4hkjD:undetectable;5vkqD-4hkjD:undetectable","5vkqC-4hkjD:8.52;5vkqD-4hkjD:8.52"]]