SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hlj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 4hlj ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 PRO A 877
ASP A 872
ASP A 882
 None
 0.74A 1sqfA-4hljA:
undetectable		 1sqfA-4hljA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4hlj ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		4 / 5 ILE A 826
LEU A 871
LYS A 786
VAL A 838
 None
 1.24A 5jmnB-4hljA:
undetectable		 5jmnB-4hljA:
13.23