SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hly'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4hly K9
(Human
gammaherpesvirus
8) 		3 / 3 LEU A  39
VAL A  54
ARG A  75
 None
 0.85A 3b0wB-4hlyA:
undetectable		 3b0wB-4hlyA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 4hly K9
(Human
gammaherpesvirus
8) 		3 / 3 HIS A 100
ARG A  48
GLU A  23
 None
 0.77A 3qf1A-4hlyA:
undetectable		 3qf1A-4hlyA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		 4hly K9
(Human
gammaherpesvirus
8) 		4 / 5 ASP A  98
HIS A 100
ARG A  48
GLU A  23
 None
 1.15A 3r4xA-4hlyA:
undetectable		 3r4xA-4hlyA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 4hly K9
(Human
gammaherpesvirus
8) 		5 / 9 LEU A  82
GLY A  61
ILE A  57
ILE A  10
ILE A   6
 None
 1.06A 3s56B-4hlyA:
undetectable		 3s56B-4hlyA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4hly K9
(Human
gammaherpesvirus
8) 		4 / 7 ASP A  98
GLU A  23
ASP A  49
GLU A  45
 None
 1.20A 4fevB-4hlyA:
undetectable		 4fevB-4hlyA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4hly K9
(Human
gammaherpesvirus
8) 		4 / 7 ASP A  98
GLU A  23
ASP A  49
GLU A  45
 None
 1.22A 4fewB-4hlyA:
undetectable		 4fewB-4hlyA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_2
(SERUM ALBUMIN)		 4hly K9
(Human
gammaherpesvirus
8) 		4 / 4 ARG A 106
GLU A  90
ASP A  26
ARG A  31
 None
 1.38A 4l9qB-4hlyA:
0.0		 4l9qB-4hlyA:
11.72