SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 4hmy ADP-RIBOSYLATION
FACTOR 1
(Homo
sapiens) 		5 / 10 LEU C 107
VAL C  23
VAL C  92
GLY C  24
LEU C 111
 None
 1.26A 1fkoA-4hmyC:
undetectable		 1fkoA-4hmyC:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4hmy ADP-RIBOSYLATION
FACTOR 1
(Homo
sapiens) 		5 / 10 ILE C  20
ILE C  89
VAL C  91
GLY C  24
LEU C 116
 None
 1.33A 3em0A-4hmyC:
undetectable		 3em0A-4hmyC:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 4hmy ADP-RIBOSYLATION
FACTOR 1
(Homo
sapiens) 		5 / 8 ASP C  96
ASN C  95
CYH C 159
THR C 161
GLY C  29
 None
None
GTP  C1001 ( 4.0A)
GTP  C1001 (-3.3A)
GTP  C1001 (-3.3A)
 1.37A 4fo4A-4hmyC:
undetectable		 4fo4A-4hmyC:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 4hmy ADP-RIBOSYLATION
FACTOR 1
(Homo
sapiens) 		4 / 5 LEU C 170
GLY C 169
ILE C  33
LYS C  36
 None
 1.11A 4ma8C-4hmyC:
undetectable		 4ma8C-4hmyC:
20.89