SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ho7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.64A 2f162-4ho7A:
20.4		 2f162-4ho7A:
28.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
ALA A  28
LYS A  34
ALA A  47
GLY A  48
 None
 0.69A 2f16H-4ho7A:
21.1
2f16I-4ho7A:
20.0		 2f16H-4ho7A:
22.92
2f16I-4ho7A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 10 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.66A 2f16K-4ho7A:
21.0
2f16L-4ho7A:
17.1		 2f16K-4ho7A:
23.26
2f16L-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.64A 2f16N-4ho7A:
20.4		 2f16N-4ho7A:
28.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
ALA A  28
LYS A  34
ALA A  47
GLY A  48
 None
 0.70A 2f16V-4ho7A:
21.2
2f16W-4ho7A:
20.4		 2f16V-4ho7A:
22.92
2f16W-4ho7A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 10 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.65A 2f16Y-4ho7A:
10.1
2f16Z-4ho7A:
5.8		 2f16Y-4ho7A:
23.26
2f16Z-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 12 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.62A 3mg02-4ho7A:
20.3
3mg0V-4ho7A:
21.1		 3mg02-4ho7A:
28.08
3mg0V-4ho7A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
LYS A  34
ALA A  47
GLY A  48
 None
 0.66A 3mg0H-4ho7A:
21.1
3mg0I-4ho7A:
19.9		 3mg0H-4ho7A:
22.92
3mg0I-4ho7A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		7 / 11 THR A   1
THR A  21
ALA A  28
LYS A  34
ALA A  47
GLY A  48
SER A 125
 None
 0.75A 3mg0K-4ho7A:
20.9
3mg0L-4ho7A:
17.1		 3mg0K-4ho7A:
23.26
3mg0L-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.63A 3mg0N-4ho7A:
20.3		 3mg0N-4ho7A:
28.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
ALA A  28
LYS A  34
ALA A  47
GLY A  48
 None
 0.70A 3mg0V-4ho7A:
21.1
3mg0W-4ho7A:
20.4		 3mg0V-4ho7A:
22.92
3mg0W-4ho7A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		7 / 12 THR A   1
THR A  21
ALA A  28
LYS A  34
ALA A  47
GLY A  48
SER A 125
 None
 0.74A 3mg0Y-4ho7A:
10.1
3mg0Z-4ho7A:
6.3		 3mg0Y-4ho7A:
23.26
3mg0Z-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.62A 4qvlK-4ho7A:
20.8
4qvlL-4ho7A:
17.0		 4qvlK-4ho7A:
23.26
4qvlL-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.62A 4qvlY-4ho7A:
10.1
4qvlZ-4ho7A:
5.7		 4qvlY-4ho7A:
23.26
4qvlZ-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 9 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.63A 4qvmK-4ho7A:
20.9
4qvmL-4ho7A:
17.0		 4qvmK-4ho7A:
23.26
4qvmL-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 10 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.62A 4qvmY-4ho7A:
10.1
4qvmZ-4ho7A:
5.8		 4qvmY-4ho7A:
23.26
4qvmZ-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 12 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.67A 4qvnV-4ho7A:
21.1
4qvnb-4ho7A:
20.3		 4qvnV-4ho7A:
23.27
4qvnb-4ho7A:
28.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 9 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.61A 4qvnK-4ho7A:
20.9
4qvnL-4ho7A:
17.0		 4qvnK-4ho7A:
23.26
4qvnL-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 12 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.66A 4qvnH-4ho7A:
6.9
4qvnN-4ho7A:
20.4		 4qvnH-4ho7A:
23.27
4qvnN-4ho7A:
28.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 9 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.62A 4qvnY-4ho7A:
10.1
4qvnZ-4ho7A:
16.1		 4qvnY-4ho7A:
23.26
4qvnZ-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 10 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.65A 4qvpK-4ho7A:
20.8
4qvpL-4ho7A:
16.8		 4qvpK-4ho7A:
23.26
4qvpL-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 10 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.66A 4qvpY-4ho7A:
10.1
4qvpZ-4ho7A:
18.2		 4qvpY-4ho7A:
23.26
4qvpZ-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 9 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.64A 4qvqK-4ho7A:
20.9
4qvqL-4ho7A:
17.1		 4qvqK-4ho7A:
23.26
4qvqL-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 9 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.64A 4qvqY-4ho7A:
10.2
4qvqZ-4ho7A:
16.8		 4qvqY-4ho7A:
23.26
4qvqZ-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
LYS A  34
ALA A  47
GLY A  48
 None
 0.75A 4qvvH-4ho7A:
20.2		 4qvvH-4ho7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		4 / 8 THR A   1
THR A  21
LYS A  34
GLY A  48
 None
 0.62A 4qvvK-4ho7A:
20.8
4qvvL-4ho7A:
17.0		 4qvvK-4ho7A:
23.26
4qvvL-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
LYS A  34
ALA A  47
GLY A  48
 None
 0.75A 4qvvV-4ho7A:
21.3		 4qvvV-4ho7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		4 / 8 THR A   1
THR A  21
LYS A  34
GLY A  48
 None
 0.62A 4qvvY-4ho7A:
8.8
4qvvZ-4ho7A:
5.8		 4qvvY-4ho7A:
23.26
4qvvZ-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.63A 4qvwK-4ho7A:
20.9
4qvwL-4ho7A:
16.9		 4qvwK-4ho7A:
23.26
4qvwL-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.63A 4qvwY-4ho7A:
8.5
4qvwZ-4ho7A:
18.1		 4qvwY-4ho7A:
23.26
4qvwZ-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
LYS A  34
ALA A  47
GLY A  48
 None
 0.76A 4qvyH-4ho7A:
20.1		 4qvyH-4ho7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.64A 4qw1K-4ho7A:
20.9
4qw1L-4ho7A:
17.0		 4qw1K-4ho7A:
22.79
4qw1L-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 10 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.64A 4qw1Y-4ho7A:
10.1
4qw1Z-4ho7A:
18.2		 4qw1Y-4ho7A:
22.79
4qw1Z-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 10 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.63A 4qw3K-4ho7A:
20.8
4qw3L-4ho7A:
17.0		 4qw3K-4ho7A:
23.26
4qw3L-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 10 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.63A 4qw3Y-4ho7A:
10.0
4qw3Z-4ho7A:
16.7		 4qw3Y-4ho7A:
23.26
4qw3Z-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 9 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.90A 4qwuK-4ho7A:
20.1
4qwuL-4ho7A:
16.8		 4qwuK-4ho7A:
23.26
4qwuL-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 9 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.88A 4qwuY-4ho7A:
10.0
4qwuZ-4ho7A:
16.8		 4qwuY-4ho7A:
23.26
4qwuZ-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.59A 5bxnK-4ho7A:
20.9
5bxnL-4ho7A:
16.7		 5bxnK-4ho7A:
23.26
5bxnL-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
LYS A  34
ALA A  47
GLY A  48
 None
 0.72A 5bxnV-4ho7A:
21.3
5bxnW-4ho7A:
20.4		 5bxnV-4ho7A:
23.27
5bxnW-4ho7A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.59A 5bxnY-4ho7A:
10.1
5bxnZ-4ho7A:
18.0		 5bxnY-4ho7A:
23.26
5bxnZ-4ho7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
LYS A  34
ALA A  47
GLY A  48
 None
 0.74A 5d0xV-4ho7A:
21.3		 5d0xV-4ho7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		3 / 3 LYS A  34
ASP A 168
ILE A  54
 None
 0.84A 5kc4E-4ho7A:
undetectable		 5kc4E-4ho7A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 12 THR A   1
THR A  21
LYS A  34
ALA A  47
GLY A  48
 None
 0.68A 5l5zH-4ho7A:
7.0
5l5zI-4ho7A:
20.0		 5l5zH-4ho7A:
23.27
5l5zI-4ho7A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 9 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.63A 5l5zK-4ho7A:
8.0
5l5zL-4ho7A:
16.9		 5l5zK-4ho7A:
24.29
5l5zL-4ho7A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 12 THR A   1
THR A  21
LYS A  34
ALA A  47
GLY A  48
 None
 0.68A 5l5zV-4ho7A:
21.3
5l5zW-4ho7A:
20.4		 5l5zV-4ho7A:
23.27
5l5zW-4ho7A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 9 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.63A 5l5zY-4ho7A:
21.0
5l5zZ-4ho7A:
16.8		 5l5zY-4ho7A:
24.29
5l5zZ-4ho7A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 10 THR A   1
THR A  21
LYS A  34
ALA A  47
GLY A  48
 None
 0.68A 5lf3V-4ho7A:
21.7
5lf3W-4ho7A:
20.2		 5lf3V-4ho7A:
23.48
5lf3W-4ho7A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 12 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.75A 5lf7V-4ho7A:
21.6
5lf7b-4ho7A:
19.8		 5lf7V-4ho7A:
23.48
5lf7b-4ho7A:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 12 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.74A 5lf7H-4ho7A:
21.6
5lf7N-4ho7A:
19.8		 5lf7H-4ho7A:
23.48
5lf7N-4ho7A:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ONL_A_010A302_0
(YNDL)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		4 / 5 GLU A  77
LYS A  80
GLU A  81
GLU A  66
 None
 1.25A 5onlA-4ho7A:
undetectable		 5onlA-4ho7A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HRJ_A_010A302_0
(YNDL)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		4 / 5 GLU A  77
LYS A  80
GLU A  81
GLU A  66
 None
 1.25A 6hrjA-4ho7A:
undetectable		 6hrjA-4ho7A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 12 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.67A 6hwdV-4ho7A:
21.3
6hwdb-4ho7A:
20.4		 6hwdV-4ho7A:
19.19
6hwdb-4ho7A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 12 THR A   1
ALA A  28
LYS A  34
ALA A  47
GLY A  48
 None
 0.69A 6hwdH-4ho7A:
20.2
6hwdI-4ho7A:
19.8		 6hwdH-4ho7A:
19.19
6hwdI-4ho7A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.67A 6hwdK-4ho7A:
21.0
6hwdL-4ho7A:
17.1		 6hwdK-4ho7A:
17.42
6hwdL-4ho7A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 12 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.68A 6hwdH-4ho7A:
20.2
6hwdN-4ho7A:
20.4		 6hwdH-4ho7A:
19.19
6hwdN-4ho7A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
ALA A  28
LYS A  34
ALA A  47
GLY A  48
 None
 0.69A 6hwdV-4ho7A:
21.3		 6hwdV-4ho7A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4ho7 HSLVU COMPLEX
PROTEOLYTIC SUBUNIT,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 THR A   1
THR A  21
ALA A  28
LYS A  34
GLY A  48
 None
 0.66A 6hwdY-4ho7A:
10.3
6hwdZ-4ho7A:
18.2		 6hwdY-4ho7A:
17.42
6hwdZ-4ho7A:
21.79