SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hoz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		6 / 12 TYR A 105
ARG A 239
GLU A 295
HIS A 368
ASP A 369
ARG A 460
 GLC  A 703 (-3.5A)
GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
GLC  A 703 ( 4.6A)
 0.84A 1dedB-4hozA:
26.8		 1dedB-4hozA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 11 ILE A  69
GLY A 476
GLY A  66
PHE A 473
ASP A  63
 None
None
None
None
CA  A 701 (-3.2A)
 1.03A 1ho5A-4hozA:
1.9		 1ho5A-4hozA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		7 / 12 TYR A 105
HIS A 145
PHE A 205
ARG A 239
GLU A 295
HIS A 368
ASP A 369
 GLC  A 703 (-3.5A)
GLC  A 703 (-4.3A)
GLC  A 703 (-3.7A)
GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
 1.00A 1mxdA-4hozA:
22.6		 1mxdA-4hozA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 ARG A 220
TYR A 276
LYS A 272
 None
 0.90A 1uujB-4hozA:
undetectable		 1uujB-4hozA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 8 PHE A 344
PHE A 551
TYR A 536
TYR A 523
 None
 1.22A 2aoxA-4hozA:
undetectable		 2aoxA-4hozA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 6 TYR A 105
ASP A 102
PHE A 205
THR A 242
 GLC  A 703 (-3.5A)
GLC  A 703 (-2.7A)
GLC  A 703 (-3.7A)
None
 1.15A 2dttB-4hozA:
undetectable
2dttC-4hozA:
undetectable		 2dttB-4hozA:
14.29
2dttC-4hozA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 ARG A 328
ASP A 322
ASP A 302
 None
 0.87A 2ejtA-4hozA:
undetectable		 2ejtA-4hozA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 ASP A 329
ARG A 336
ARG A 335
 None
 0.87A 2j9dA-4hozA:
undetectable
2j9dC-4hozA:
undetectable		 2j9dA-4hozA:
12.93
2j9dC-4hozA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 GLY A  86
ASP A  88
ILE A 511
THR A 396
ILE A 405
 None
 0.87A 2nmyA-4hozA:
undetectable		 2nmyA-4hozA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 7 GLY A 298
THR A 268
PHE A 205
PHE A 186
 None
None
GLC  A 703 (-3.7A)
GLC  A 703 (-4.8A)
 0.98A 2qx4A-4hozA:
undetectable
2qx4B-4hozA:
undetectable		 2qx4A-4hozA:
16.82
2qx4B-4hozA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 ARG A 239
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-2.7A)
 0.76A 3aicA-4hozA:
4.5		 3aicA-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 ARG A 239
GLU A 295
HIS A 368
ASP A 369
GLN A 209
 GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-3.8A)
 0.92A 3aicA-4hozA:
4.5		 3aicA-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 ARG A 239
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-2.7A)
 0.78A 3aicB-4hozA:
3.9		 3aicB-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		6 / 12 ARG A 239
GLU A 295
HIS A 368
ASP A 369
ASP A 102
TYR A 105
 GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-2.7A)
GLC  A 703 (-3.5A)
 0.73A 3aicC-4hozA:
3.4		 3aicC-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		6 / 12 ARG A 239
GLU A 295
HIS A 368
ASP A 369
TYR A 105
GLN A 209
 GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-3.5A)
GLC  A 703 (-3.8A)
 0.99A 3aicC-4hozA:
3.4		 3aicC-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 ARG A 239
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-2.7A)
 0.84A 3aicD-4hozA:
4.2		 3aicD-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 ARG A 239
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-2.7A)
 0.84A 3aicE-4hozA:
7.6		 3aicE-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 ARG A 239
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-2.7A)
 0.81A 3aicF-4hozA:
7.6		 3aicF-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 ARG A 239
GLU A 295
HIS A 368
ASP A 369
GLN A 209
 GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-3.8A)
 0.89A 3aicF-4hozA:
7.6		 3aicF-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 ARG A 239
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-2.7A)
 0.78A 3aicG-4hozA:
7.3		 3aicG-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 ARG A 239
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-2.7A)
 0.81A 3aicH-4hozA:
4.2		 3aicH-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 ARG A 239
GLU A 295
HIS A 368
ASP A 369
GLN A 209
 GLC  A 703 (-2.9A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-4.0A)
GLC  A 703 ( 2.8A)
GLC  A 703 (-3.8A)
 0.96A 3aicH-4hozA:
4.2		 3aicH-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 8 HIS A 368
ASN A 370
ILE A 324
PHE A 319
 GLC  A 703 (-4.0A)
None
None
None
 1.48A 3ccfB-4hozA:
undetectable		 3ccfB-4hozA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 5 PRO A  94
ILE A  92
PRO A  58
TYR A  57
 None
 1.05A 3d9lA-4hozA:
undetectable
3d9lY-4hozA:
undetectable		 3d9lA-4hozA:
13.60
3d9lY-4hozA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 ARG A 512
ILE A 317
TRP A 360
 None
 0.98A 3e68A-4hozA:
undetectable		 3e68A-4hozA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 11 GLY A  86
ASP A  88
ILE A 511
THR A 396
ILE A 405
 None
 0.95A 3ekxA-4hozA:
undetectable		 3ekxA-4hozA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 7 ILE A 515
GLY A 521
TYR A 536
VAL A 547
 None
 0.94A 3elzA-4hozA:
2.4		 3elzA-4hozA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 10 ILE A 511
ILE A 515
GLY A 521
TYR A 536
VAL A 547
 None
 1.16A 3elzC-4hozA:
2.3		 3elzC-4hozA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 10 ILE A 511
ILE A 515
GLY A 521
TYR A 536
VAL A 547
 None
 1.17A 3em0A-4hozA:
1.8		 3em0A-4hozA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG8_A_TOYA305_1
(APH(2'')-ID)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 ASN A 103
SER A 455
ASP A 369
TYR A  57
TRP A 479
 None
None
GLC  A 703 ( 2.8A)
None
None
 1.28A 3sg8A-4hozA:
2.8		 3sg8A-4hozA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 LYS A 269
SER A 256
GLN A 259
 None
 1.21A 3si7A-4hozA:
undetectable		 3si7A-4hozA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 8 PHE A 551
ALA A 388
PHE A 377
ALA A 373
 None
 1.03A 3t3sE-4hozA:
undetectable		 3t3sE-4hozA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 LEU A 560
PRO A 561
LEU A 564
 None
 0.40A 3w1wB-4hozA:
2.9		 3w1wB-4hozA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 ARG A 335
GLU A 446
ASN A 450
 None
 0.71A 4imaD-4hozA:
9.8		 4imaD-4hozA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 ARG A 335
GLU A 446
ASN A 450
 None
 0.69A 4ip7D-4hozA:
5.8		 4ip7D-4hozA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 LEU A 227
MET A 226
ASP A 275
 None
 0.79A 4j7xB-4hozA:
undetectable		 4j7xB-4hozA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 8 PRO A  99
ASP A 106
ALA A 206
SER A 147
 None
 0.95A 4k0bB-4hozA:
undetectable		 4k0bB-4hozA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 8 PRO A  99
ASP A 106
ALA A 206
SER A 147
 None
 0.96A 4l7iB-4hozA:
undetectable		 4l7iB-4hozA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 4 ASN A 100
GLY A 104
ASP A 124
ASP A  97
 None
 1.18A 4n49A-4hozA:
undetectable		 4n49A-4hozA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 MET A 280
VAL A 277
ILE A 143
PHE A 321
ALA A 244
 None
 1.10A 4o1zB-4hozA:
undetectable		 4o1zB-4hozA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_A_ASCA501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 11 THR A 519
HIS A 513
GLN A  50
ASP A  88
ALA A  89
 None
 1.15A 4rp8A-4hozA:
0.0		 4rp8A-4hozA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP9_A_ASCA501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 THR A 519
HIS A 513
GLN A  50
ASP A  88
ALA A  89
 None
 1.14A 4rp9A-4hozA:
undetectable		 4rp9A-4hozA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 ARG A 381
GLN A 383
GLU A 553
 None
 0.81A 4tvtA-4hozA:
undetectable		 4tvtA-4hozA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 7 TYR A  81
TYR A  54
SER A 409
LEU A 411
 None
 1.17A 5bphB-4hozA:
undetectable		 5bphB-4hozA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 GLU A 386
TRP A 384
ASN A 573
 None
 1.02A 5dv4A-4hozA:
undetectable		 5dv4A-4hozA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 6 LEU A 341
LEU A 323
PHE A 551
LEU A 395
 None
 0.89A 5gs4A-4hozA:
undetectable		 5gs4A-4hozA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 5 LEU A 341
LEU A 323
PHE A 551
LEU A 395
 None
 0.79A 5gtrA-4hozA:
undetectable		 5gtrA-4hozA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 GLY A  68
ASP A  63
ASN A  73
 None
CA  A 701 (-3.2A)
None
 0.60A 5jglA-4hozA:
undetectable		 5jglA-4hozA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 7 VAL A 548
LEU A 588
ALA A 535
LEU A 598
 None
 0.68A 5jq7A-4hozA:
undetectable		 5jq7A-4hozA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 GLU A 428
VAL A 427
ASP A 426
ALA A 206
GLY A 104
 GOL  A 702 (-3.1A)
None
None
None
None
 1.29A 5syeB-4hozA:
2.3		 5syeB-4hozA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 ASN A 100
GLY A 104
GLY A  70
SER A  60
ILE A  69
 None
None
CA  A 701 ( 4.7A)
None
None
 1.17A 5vooB-4hozA:
10.0		 5vooB-4hozA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 ARG A 460
PHE A 186
ARG A 456
 GLC  A 703 ( 4.6A)
GLC  A 703 (-4.8A)
GLC  A 703 ( 2.9A)
 1.25A 5y9yA-4hozA:
undetectable		 5y9yA-4hozA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		3 / 3 ASP A 435
PHE A 263
ARG A 333
 None
 1.16A 5yw0A-4hozA:
undetectable		 5yw0A-4hozA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		5 / 12 VAL A 548
LEU A 588
ALA A 535
LEU A 598
LEU A 586
 None
 0.81A 6f6iA-4hozA:
undetectable
6f6iB-4hozA:
undetectable		 6f6iA-4hozA:
9.96
6f6iB-4hozA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 7 TRP A 230
HIS A  95
ARG A 239
ASP A 140
 None
None
GLC  A 703 (-2.9A)
None
 1.29A 6mn4E-4hozA:
undetectable		 6mn4E-4hozA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 4hoz SUCROSE ISOMERASE
(Erwinia
rhapontici) 		4 / 7 GLY A  70
HIS A 368
ASN A  93
GLY A 104
 CA  A 701 ( 4.7A)
GLC  A 703 (-4.0A)
None
None
 0.91A 6n7fA-4hozA:
undetectable		 6n7fA-4hozA:
9.49