SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hpm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 4hpm BCL-6
COREPRESSOR-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 4 THR A1667
LEU A1666
VAL A1660
LEU A1611
 None
 0.90A 1fbmD-4hpmA:
undetectable		 1fbmD-4hpmA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4hpm BCL-6
COREPRESSOR-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 4 THR A1667
LEU A1666
VAL A1660
LEU A1611
 None
 0.99A 1mz9D-4hpmA:
undetectable		 1mz9D-4hpmA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4hpm BCL-6
COREPRESSOR-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 6 LEU A1689
VAL A1690
ILE A1648
TYR A1657
 None
 1.02A 1s9qA-4hpmA:
undetectable		 1s9qA-4hpmA:
17.79