SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hpn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		3 / 3 TRP A 298
ARG A 374
THR A 300
 None
 0.82A 1df7A-4hpnA:
undetectable		 1df7A-4hpnA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		3 / 3 ARG A 338
ARG A 155
ARG A  29
 None
 1.04A 1l7fA-4hpnA:
undetectable		 1l7fA-4hpnA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		3 / 3 ARG A 338
ARG A 155
ARG A  29
 None
 1.03A 1l7hA-4hpnA:
undetectable		 1l7hA-4hpnA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 8 TYR A 132
GLN A 267
HIS A 197
SER A  23
 None
 1.30A 1nx9A-4hpnA:
undetectable		 1nx9A-4hpnA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 8 TYR A 132
GLN A 267
HIS A 197
SER A  23
 None
 1.31A 1nx9B-4hpnA:
undetectable		 1nx9B-4hpnA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 8 TYR A 132
GLN A 267
HIS A 197
SER A  23
 None
 1.30A 1nx9C-4hpnA:
undetectable		 1nx9C-4hpnA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 8 TYR A 132
GLN A 267
HIS A 197
SER A  23
 None
 1.32A 1nx9D-4hpnA:
undetectable		 1nx9D-4hpnA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 8 GLY A 290
THR A 287
ALA A 286
VAL A 294
 None
 0.86A 2a1hA-4hpnA:
undetectable
2a1hB-4hpnA:
undetectable		 2a1hA-4hpnA:
22.12
2a1hB-4hpnA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		5 / 11 VAL A 224
GLU A 203
ALA A 204
PRO A 222
PHE A 219
 None
 1.33A 2admB-4hpnA:
undetectable		 2admB-4hpnA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 5 SER A 116
ASP A 357
PRO A 356
SER A 118
 None
 1.38A 2hdnA-4hpnA:
undetectable
2hdnB-4hpnA:
undetectable
2hdnD-4hpnA:
1.9		 2hdnA-4hpnA:
9.56
2hdnB-4hpnA:
23.66
2hdnD-4hpnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 5 SER A 118
SER A 116
ASP A 357
PRO A 356
 None
 1.31A 2hdnB-4hpnA:
undetectable
2hdnC-4hpnA:
undetectable
2hdnD-4hpnA:
2.0		 2hdnB-4hpnA:
23.66
2hdnC-4hpnA:
9.56
2hdnD-4hpnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 6 LEU A 207
ASN A 148
ILE A 216
PHE A 219
 None
 1.21A 2jn3A-4hpnA:
undetectable		 2jn3A-4hpnA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 7 ARG A   7
GLY A 100
VAL A 302
ASP A 102
 None
 0.95A 2y05A-4hpnA:
undetectable
2y05B-4hpnA:
undetectable		 2y05A-4hpnA:
21.77
2y05B-4hpnA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 4 LEU A  33
ARG A 343
LEU A 342
ALA A 369
 None
 1.05A 3b9mA-4hpnA:
undetectable		 3b9mA-4hpnA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 ILE A 355
VAL A 129
LEU A 270
PRO A 295
LEU A 361
 None
 1.10A 3em0B-4hpnA:
undetectable		 3em0B-4hpnA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		3 / 3 ASP A  39
ARG A  72
LYS A   1
 None
 1.15A 3wipG-4hpnA:
undetectable		 3wipG-4hpnA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_B_T3B1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 ARG A  28
PHE A  26
PHE A  19
ARG A  29
GLU A  12
 None
 1.34A 4bvaB-4hpnA:
undetectable		 4bvaB-4hpnA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 ALA A 305
GLY A  46
GLY A 362
GLY A  44
ILE A 117
 None
 1.01A 4q5mA-4hpnA:
undetectable		 4q5mA-4hpnA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 6 SER A 277
GLU A 278
GLY A  44
GLY A  46
 None
 0.88A 5cdnA-4hpnA:
undetectable
5cdnB-4hpnA:
undetectable		 5cdnA-4hpnA:
22.76
5cdnB-4hpnA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 6 SER A 277
GLU A 278
GLY A  44
GLY A  46
 None
 0.94A 5cdnR-4hpnA:
undetectable
5cdnS-4hpnA:
undetectable		 5cdnR-4hpnA:
22.76
5cdnS-4hpnA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		5 / 9 ALA A 305
GLN A 303
PRO A 345
LEU A 342
ILE A 363
 None
 1.43A 5i73A-4hpnA:
undetectable		 5i73A-4hpnA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4hpn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 4 GLY A  46
LEU A  33
VAL A 302
GLU A  47
 None
 1.31A 5yw0A-4hpnA:
undetectable		 5yw0A-4hpnA:
20.55