SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hqb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3R_B_9PLB501_1 (CYTOCHROME P450 2A6)	4hqb	SINGLE-STRANDED DNA-BINDING PROTEIN DDRB (Deinococcus radiodurans)	5 / 9	PHE A 56 VAL A 75 PHE A 48 ILE A 61 PHE A 131	None	1.17A	3t3rB-4hqbA: undetectable	3t3rB-4hqbA: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3R_D_9PLD501_1 (CYTOCHROME P450 2A6)	4hqb	SINGLE-STRANDED DNA-BINDING PROTEIN DDRB (Deinococcus radiodurans)	5 / 10	PHE A 56 VAL A 75 PHE A 48 ILE A 61 PHE A 131	None	1.23A	3t3rD-4hqbA: undetectable	3t3rD-4hqbA: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5F1A_A_SALA601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4hqb	SINGLE-STRANDED DNA-BINDING PROTEIN DDRB (Deinococcus radiodurans)	4 / 8	VAL A 115 TYR A 82 GLY A 106 ALA A 107	None	0.73A	5f1aA-4hqbA: undetectable	5f1aA-4hqbA: 13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5F1A_B_SALB601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4hqb	SINGLE-STRANDED DNA-BINDING PROTEIN DDRB (Deinococcus radiodurans)	4 / 7	VAL A 115 TYR A 82 GLY A 106 ALA A 107	None	0.75A	5f1aB-4hqbA: undetectable	5f1aB-4hqbA: 13.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3T3R_B_9PLB501_1","CYTOCHROME P450 2A6","4hqb","SINGLE-STRANDED DNA-BINDING PROTEIN DDRB","Deinococcus radiodurans",5,"PHE A  56;VAL A  75;PHE A  48;ILE A  61;PHE A 131","None","1.17A","3t3rB-4hqbA:undetectable","3t3rB-4hqbA:16.96"],["3T3R_D_9PLD501_1","CYTOCHROME P450 2A6","4hqb","SINGLE-STRANDED DNA-BINDING PROTEIN DDRB","Deinococcus radiodurans",5,"PHE A  56;VAL A  75;PHE A  48;ILE A  61;PHE A 131","None","1.23A","3t3rD-4hqbA:undetectable","3t3rD-4hqbA:16.96"],["5F1A_A_SALA601_1","PROSTAGLANDIN G\/H SYNTHASE 2","4hqb","SINGLE-STRANDED DNA-BINDING PROTEIN DDRB","Deinococcus radiodurans",4,"VAL A 115;TYR A  82;GLY A 106;ALA A 107","None","0.73A","5f1aA-4hqbA:undetectable","5f1aA-4hqbA:13.36"],["5F1A_B_SALB601_1","PROSTAGLANDIN G\/H SYNTHASE 2","4hqb","SINGLE-STRANDED DNA-BINDING PROTEIN DDRB","Deinococcus radiodurans",4,"VAL A 115;TYR A  82;GLY A 106;ALA A 107","None","0.75A","5f1aB-4hqbA:undetectable","5f1aB-4hqbA:13.36"]]