SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hqf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 8 ARG A 176
LEU A 172
GLN A 169
PHE A 198
LEU A 202
 None
 1.21A 1v54C-4hqfA:
undetectable
1v54J-4hqfA:
undetectable		 1v54C-4hqfA:
20.74
1v54J-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 8 ARG A 176
LYS A 173
LEU A 172
PHE A 198
LEU A 202
 None
 1.11A 1v54C-4hqfA:
undetectable
1v54J-4hqfA:
undetectable		 1v54C-4hqfA:
20.74
1v54J-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 8 ARG A 176
LEU A 172
GLN A 169
PHE A 198
LEU A 202
 None
 1.22A 1v54P-4hqfA:
undetectable
1v54W-4hqfA:
undetectable		 1v54P-4hqfA:
20.74
1v54W-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 8 ARG A 176
LYS A 173
LEU A 172
PHE A 198
LEU A 202
 None
 1.12A 1v54P-4hqfA:
undetectable
1v54W-4hqfA:
undetectable		 1v54P-4hqfA:
20.74
1v54W-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 7 ARG A 176
LYS A 173
LEU A 172
LEU A 202
 None
 1.09A 1v55C-4hqfA:
undetectable
1v55J-4hqfA:
undetectable		 1v55C-4hqfA:
20.74
1v55J-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 8 ARG A 176
LEU A 172
GLN A 169
PHE A 198
LEU A 202
 None
 1.21A 2dyrC-4hqfA:
undetectable
2dyrJ-4hqfA:
undetectable		 2dyrC-4hqfA:
20.74
2dyrJ-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 8 ARG A 176
LYS A 173
LEU A 172
PHE A 198
LEU A 202
 None
 1.10A 2dyrC-4hqfA:
undetectable
2dyrJ-4hqfA:
undetectable		 2dyrC-4hqfA:
20.74
2dyrJ-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 8 ARG A 176
LEU A 172
GLN A 169
PHE A 198
LEU A 202
 None
 1.22A 2dyrP-4hqfA:
undetectable
2dyrW-4hqfA:
undetectable		 2dyrP-4hqfA:
20.74
2dyrW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 8 ARG A 176
LYS A 173
LEU A 172
PHE A 198
LEU A 202
 None
 1.13A 2dyrP-4hqfA:
undetectable
2dyrW-4hqfA:
undetectable		 2dyrP-4hqfA:
20.74
2dyrW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 7 ARG A 176
LYS A 173
LEU A 172
LEU A 202
 None
 1.03A 2dysP-4hqfA:
undetectable
2dysW-4hqfA:
undetectable		 2dysP-4hqfA:
20.74
2dysW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 8 ARG A 176
LEU A 172
GLN A 169
PHE A 198
LEU A 202
 None
 1.23A 2eikP-4hqfA:
undetectable
2eikW-4hqfA:
undetectable		 2eikP-4hqfA:
20.74
2eikW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 8 ARG A 176
LYS A 173
LEU A 172
PHE A 198
LEU A 202
 None
 1.14A 2eikP-4hqfA:
undetectable
2eikW-4hqfA:
undetectable		 2eikP-4hqfA:
20.74
2eikW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 8 ARG A 176
LYS A 173
LEU A 172
PHE A 198
LEU A 202
 None
 1.12A 2eilC-4hqfA:
undetectable
2eilJ-4hqfA:
undetectable		 2eilC-4hqfA:
20.74
2eilJ-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 7 ARG A 176
LYS A 173
LEU A 172
LEU A 202
 None
 1.05A 2eimC-4hqfA:
undetectable
2eimJ-4hqfA:
undetectable		 2eimC-4hqfA:
20.74
2eimJ-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 7 ARG A 176
LYS A 173
LEU A 172
PHE A 198
LEU A 202
 None
 1.03A 2eimP-4hqfA:
undetectable
2eimW-4hqfA:
undetectable		 2eimP-4hqfA:
20.74
2eimW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QK8_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 12 VAL A 226
LYS A 224
ILE A 190
LEU A  71
PHE A 188
 None
 1.22A 2qk8A-4hqfA:
undetectable		 2qk8A-4hqfA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 ARG A 176
GLN A 169
PHE A 198
LEU A 202
 None
 1.04A 3ablP-4hqfA:
undetectable
3ablW-4hqfA:
undetectable		 3ablP-4hqfA:
20.74
3ablW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 7 ARG A 176
LEU A 172
PHE A 198
LEU A 202
 None
 0.99A 3ag2C-4hqfA:
undetectable		 3ag2C-4hqfA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 7 ARG A 176
LEU A 172
PHE A 198
LEU A 202
 None
 1.00A 3ag2P-4hqfA:
undetectable
3ag2W-4hqfA:
undetectable		 3ag2P-4hqfA:
20.74
3ag2W-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 8 ARG A 176
LEU A 172
GLN A 169
PHE A 198
LEU A 202
 None
 1.21A 3ag4C-4hqfA:
undetectable
3ag4J-4hqfA:
undetectable		 3ag4C-4hqfA:
20.74
3ag4J-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 7 ARG A 176
LEU A 172
GLN A 169
PHE A 198
LEU A 202
 None
 1.20A 3asnC-4hqfA:
undetectable
3asnJ-4hqfA:
undetectable		 3asnC-4hqfA:
20.74
3asnJ-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 7 ARG A 176
LYS A 173
LEU A 172
PHE A 198
LEU A 202
 None
 1.14A 3asnP-4hqfA:
undetectable
3asnW-4hqfA:
undetectable		 3asnP-4hqfA:
20.74
3asnW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 7 ARG A 176
LYS A 173
LEU A 172
PHE A 198
LEU A 202
 None
 1.09A 3asoP-4hqfA:
undetectable
3asoW-4hqfA:
undetectable		 3asoP-4hqfA:
20.74
3asoW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 12 ILE A 159
LYS A 130
THR A 161
VAL A 187
SER A 171
 None
None
None
None
CL  A 401 ( 3.9A)
 1.19A 3kpdB-4hqfA:
undetectable		 3kpdB-4hqfA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		3 / 3 ASN A 152
ASN A 154
GLU A 239
 None
 0.86A 3kpdC-4hqfA:
undetectable		 3kpdC-4hqfA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		3 / 3 ASN A 152
ASN A 154
GLU A 239
 None
 0.69A 3kpdB-4hqfA:
undetectable		 3kpdB-4hqfA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		3 / 3 GLU A 239
GLU A  41
ASN A  44
 None
 0.91A 3lp9B-4hqfA:
undetectable
3lp9D-4hqfA:
undetectable		 3lp9B-4hqfA:
19.64
3lp9D-4hqfA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 12 LEU A 122
ILE A 118
LEU A 160
LEU A  88
LEU A 156
 None
 1.22A 3vw1B-4hqfA:
undetectable		 3vw1B-4hqfA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 ARG A 176
LEU A 172
PHE A 198
LEU A 202
 None
 0.98A 3wg7C-4hqfA:
undetectable
3wg7J-4hqfA:
undetectable		 3wg7C-4hqfA:
20.74
3wg7J-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 ARG A 176
LEU A 172
PHE A 198
LEU A 202
 None
 0.97A 3wg7P-4hqfA:
undetectable
3wg7W-4hqfA:
undetectable		 3wg7P-4hqfA:
20.74
3wg7W-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 7 ARG A 176
LEU A 172
PHE A 198
LEU A 202
 None
 0.99A 3x2qP-4hqfA:
undetectable
3x2qW-4hqfA:
undetectable		 3x2qP-4hqfA:
20.74
3x2qW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 ARG A 176
GLN A 169
PHE A 198
LEU A 202
 None
 1.00A 5b1bC-4hqfA:
undetectable
5b1bJ-4hqfA:
undetectable		 5b1bC-4hqfA:
20.74
5b1bJ-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 7 ARG A 176
LEU A 172
GLN A 169
PHE A 198
LEU A 202
 None
 1.25A 5b1bP-4hqfA:
undetectable
5b1bW-4hqfA:
undetectable		 5b1bP-4hqfA:
20.74
5b1bW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 SER A 171
GLU A 174
GLY A  57
GLY A  55
 CL  A 401 ( 3.9A)
None
None
None
 0.63A 5cdnA-4hqfA:
undetectable
5cdnB-4hqfA:
undetectable		 5cdnA-4hqfA:
19.21
5cdnB-4hqfA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 SER A 171
GLU A 174
GLY A  57
GLY A  55
 CL  A 401 ( 3.9A)
None
None
None
 0.68A 5cdnR-4hqfA:
undetectable
5cdnS-4hqfA:
2.2		 5cdnR-4hqfA:
19.21
5cdnS-4hqfA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 ARG A 176
LYS A 173
LEU A 172
LEU A 202
 None
 1.08A 5w97C-4hqfA:
undetectable
5w97J-4hqfA:
undetectable		 5w97C-4hqfA:
20.74
5w97J-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 5 ARG A 176
LEU A 172
PHE A 198
LEU A 202
 None
 0.98A 5x19C-4hqfA:
undetectable
5x19J-4hqfA:
undetectable		 5x19C-4hqfA:
20.74
5x19J-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 6 ARG A 176
LYS A 173
LEU A 172
PHE A 198
LEU A 202
 None
 1.09A 5x19P-4hqfA:
undetectable		 5x19P-4hqfA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 5 ARG A 176
LEU A 172
PHE A 198
LEU A 202
 None
 0.94A 5x1bP-4hqfA:
undetectable		 5x1bP-4hqfA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 7 ARG A 176
LYS A 173
LEU A 172
PHE A 198
LEU A 202
 None
 1.07A 5x1fP-4hqfA:
undetectable
5x1fW-4hqfA:
undetectable		 5x1fP-4hqfA:
20.74
5x1fW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 ARG A 176
GLN A 169
PHE A 198
LEU A 202
 None
 1.10A 5z84P-4hqfA:
undetectable
5z84W-4hqfA:
undetectable		 5z84P-4hqfA:
20.74
5z84W-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 ARG A 176
GLN A 169
PHE A 198
LEU A 202
 None
 1.12A 5z85P-4hqfA:
undetectable
5z85W-4hqfA:
undetectable		 5z85P-4hqfA:
20.74
5z85W-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 ARG A 176
GLN A 169
PHE A 198
LEU A 202
 None
 1.07A 5z86C-4hqfA:
undetectable
5z86J-4hqfA:
undetectable		 5z86C-4hqfA:
20.74
5z86J-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 ARG A 176
GLN A 169
PHE A 198
LEU A 202
 None
 1.10A 5z86P-4hqfA:
undetectable
5z86W-4hqfA:
undetectable		 5z86P-4hqfA:
20.74
5z86W-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 ARG A 176
GLN A 169
PHE A 198
LEU A 202
 None
 1.10A 5zcoP-4hqfA:
undetectable
5zcoW-4hqfA:
undetectable		 5zcoP-4hqfA:
20.74
5zcoW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 ARG A 176
GLN A 169
PHE A 198
LEU A 202
 None
 1.05A 5zcpC-4hqfA:
undetectable
5zcpJ-4hqfA:
undetectable		 5zcpC-4hqfA:
20.74
5zcpJ-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		4 / 6 ARG A 176
GLN A 169
PHE A 198
LEU A 202
 None
 1.09A 5zcpP-4hqfA:
undetectable
5zcpW-4hqfA:
undetectable		 5zcpP-4hqfA:
20.74
5zcpW-4hqfA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4hqf THROMBOSPONDIN-RELAT
ED ANONYMOUS
PROTEIN, TRAP
(Plasmodium
falciparum) 		5 / 9 LEU A 160
GLY A 228
LEU A  75
GLN A  77
VAL A 223
 None
 1.26A 6czmA-4hqfA:
undetectable
6czmB-4hqfA:
undetectable		 6czmA-4hqfA:
23.27
6czmB-4hqfA:
23.27