SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hri'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HRE_D_CHDD702_0 (FERROCHELATASE)	4hri	HETEROCYST DIFFERENTIATION CONTROL PROTEIN (Nostoc sp. PCC 7120)	3 / 3	ARG B 10 GLY B 12 PRO B 13	None	0.69A	2hreD-4hriB: undetectable	2hreD-4hriB: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOA_A_ACRA1587_2 (TREHALOSE SYNTHASE/AMYLASE TRES)	4hri	HETEROCYST DIFFERENTIATION CONTROL PROTEIN (Nostoc sp. PCC 7120)	3 / 3	ARG B 165 PHE B 106 PRO B 107	None	0.89A	3zoaB-4hriB: undetectable	3zoaB-4hriB: 21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AZS_A_SAMA1475_1 (METHYLTRANSFERASE WBDD)	4hri	HETEROCYST DIFFERENTIATION CONTROL PROTEIN (Nostoc sp. PCC 7120)	3 / 3	ARG B 223 ASP B 270 GLN B 267	None	0.92A	4azsA-4hriB: undetectable	4azsA-4hriB: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2X_E_TMQE202_1 (DIHYDROFOLATE REDUCTASE)	4hri	HETEROCYST DIFFERENTIATION CONTROL PROTEIN (Nostoc sp. PCC 7120)	5 / 12	ILE B 104 LEU B 178 LEU B 182 ILE B 186 TYR B 108	None	1.06A	4m2xE-4hriB: undetectable	4m2xE-4hriB: 19.81

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2HRE_D_CHDD702_0","FERROCHELATASE","4hri","HETEROCYST DIFFERENTIATION CONTROL PROTEIN","Nostoc sp. PCC 7120",3,"ARG B  10;GLY B  12;PRO B  13","None","0.69A","2hreD-4hriB:undetectable","2hreD-4hriB:22.25"],["3ZOA_A_ACRA1587_2","TREHALOSE SYNTHASE\/AMYLASE TRES;TREHALOSE SYNTHASE\/AMYLASE TRES","4hri","HETEROCYST DIFFERENTIATION CONTROL PROTEIN","Nostoc sp. PCC 7120",3,"ARG B 165;PHE B 106;PRO B 107","None","0.89A","3zoaB-4hriB:undetectable","3zoaB-4hriB:21.37"],["4AZS_A_SAMA1475_1","METHYLTRANSFERASE WBDD","4hri","HETEROCYST DIFFERENTIATION CONTROL PROTEIN","Nostoc sp. PCC 7120",3,"ARG B 223;ASP B 270;GLN B 267","None","0.92A","4azsA-4hriB:undetectable","4azsA-4hriB:21.15"],["4M2X_E_TMQE202_1","DIHYDROFOLATE REDUCTASE","4hri","HETEROCYST DIFFERENTIATION CONTROL PROTEIN","Nostoc sp. PCC 7120",5,"ILE B 104;LEU B 178;LEU B 182;ILE B 186;TYR B 108","None","1.06A","4m2xE-4hriB:undetectable","4m2xE-4hriB:19.81"]]