SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hrv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_A_GLYA1292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4hrv	PUTATIVE LIPOPROTEIN GNA1162 (Neisseria meningitidis)	4 / 8	SER A 37 HIS A 101 SER A 139 PHE A 72	None	1.33A	1eqbA-4hrvA: undetectable 1eqbB-4hrvA: undetectable	1eqbA-4hrvA: 17.14 1eqbB-4hrvA: 17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CDQ_A_SAMA1500_0 (ASPARTOKINASE)	4hrv	PUTATIVE LIPOPROTEIN GNA1162 (Neisseria meningitidis)	4 / 8	ILE A 38 SER A 37 ASP A 107 LEU A 136	None	0.77A	2cdqA-4hrvA: undetectable	2cdqA-4hrvA: 16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WXO_A_NIZA802_1 (CATALASE-PEROXIDASE)	4hrv	PUTATIVE LIPOPROTEIN GNA1162 (Neisseria meningitidis)	4 / 8	TRP A 146 LEU A 110 ILE A 38 GLY A 68	None	0.88A	3wxoA-4hrvA: undetectable	3wxoA-4hrvA: 14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EWU_A_BEZA1401_0 (MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC)	4hrv	PUTATIVE LIPOPROTEIN GNA1162 (Neisseria meningitidis)	4 / 6	GLY A 52 THR A 53 SER A 47 VAL A 114	None	1.11A	5ewuA-4hrvA: undetectable	5ewuA-4hrvA: 19.39

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQB_A_GLYA1292_0","SERINE HYDROXYMETHYLTRANSFERASE","4hrv","PUTATIVE LIPOPROTEIN GNA1162","Neisseria meningitidis",4,"SER A  37;HIS A 101;SER A 139;PHE A  72","None","1.33A","1eqbA-4hrvA:undetectable;1eqbB-4hrvA:undetectable","1eqbA-4hrvA:17.14;1eqbB-4hrvA:17.14"],["2CDQ_A_SAMA1500_0","ASPARTOKINASE","4hrv","PUTATIVE LIPOPROTEIN GNA1162","Neisseria meningitidis",4,"ILE A  38;SER A  37;ASP A 107;LEU A 136","None","0.77A","2cdqA-4hrvA:undetectable","2cdqA-4hrvA:16.91"],["3WXO_A_NIZA802_1","CATALASE-PEROXIDASE","4hrv","PUTATIVE LIPOPROTEIN GNA1162","Neisseria meningitidis",4,"TRP A 146;LEU A 110;ILE A  38;GLY A  68","None","0.88A","3wxoA-4hrvA:undetectable","3wxoA-4hrvA:14.22"],["5EWU_A_BEZA1401_0","MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC","4hrv","PUTATIVE LIPOPROTEIN GNA1162","Neisseria meningitidis",4,"GLY A  52;THR A  53;SER A  47;VAL A 114","None","1.11A","5ewuA-4hrvA:undetectable","5ewuA-4hrvA:19.39"]]