SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hsu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.96A 1c9sA-4hsuA:
undetectable
1c9sK-4hsuA:
undetectable
1c9sA-4hsuA:
7.64
1c9sK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 1c9sA-4hsuA:
undetectable
1c9sB-4hsuA:
undetectable
1c9sA-4hsuA:
7.64
1c9sB-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 1c9sB-4hsuA:
undetectable
1c9sC-4hsuA:
undetectable
1c9sB-4hsuA:
7.64
1c9sC-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 1c9sC-4hsuA:
undetectable
1c9sD-4hsuA:
undetectable
1c9sC-4hsuA:
7.64
1c9sD-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.95A 1c9sD-4hsuA:
undetectable
1c9sE-4hsuA:
undetectable
1c9sD-4hsuA:
7.64
1c9sE-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 1c9sE-4hsuA:
undetectable
1c9sF-4hsuA:
undetectable
1c9sE-4hsuA:
7.64
1c9sF-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.95A 1c9sF-4hsuA:
undetectable
1c9sG-4hsuA:
undetectable
1c9sF-4hsuA:
7.64
1c9sG-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 1c9sG-4hsuA:
undetectable
1c9sH-4hsuA:
undetectable
1c9sG-4hsuA:
7.64
1c9sH-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 1c9sH-4hsuA:
undetectable
1c9sI-4hsuA:
undetectable
1c9sH-4hsuA:
7.64
1c9sI-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 8 SER A 811
GLY A 389
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
0.81A 1c9sI-4hsuA:
undetectable
1c9sJ-4hsuA:
undetectable
1c9sI-4hsuA:
7.64
1c9sJ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.92A 1c9sJ-4hsuA:
undetectable
1c9sK-4hsuA:
undetectable
1c9sJ-4hsuA:
7.64
1c9sK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.97A 1c9sL-4hsuA:
undetectable
1c9sM-4hsuA:
undetectable
1c9sL-4hsuA:
7.64
1c9sM-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.96A 1c9sM-4hsuA:
undetectable
1c9sN-4hsuA:
undetectable
1c9sM-4hsuA:
7.64
1c9sN-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 1c9sN-4hsuA:
undetectable
1c9sO-4hsuA:
undetectable
1c9sN-4hsuA:
7.64
1c9sO-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.97A 1c9sO-4hsuA:
undetectable
1c9sP-4hsuA:
undetectable
1c9sO-4hsuA:
7.64
1c9sP-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 1c9sP-4hsuA:
undetectable
1c9sQ-4hsuA:
undetectable
1c9sP-4hsuA:
7.64
1c9sQ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.96A 1c9sQ-4hsuA:
undetectable
1c9sR-4hsuA:
undetectable
1c9sQ-4hsuA:
7.64
1c9sR-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 1c9sS-4hsuA:
undetectable
1c9sT-4hsuA:
undetectable
1c9sS-4hsuA:
7.64
1c9sT-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.98A 1c9sL-4hsuA:
undetectable
1c9sV-4hsuA:
undetectable
1c9sL-4hsuA:
7.64
1c9sV-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.94A 1gtfA-4hsuA:
undetectable
1gtfK-4hsuA:
undetectable
1gtfA-4hsuA:
7.64
1gtfK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.92A 1gtfA-4hsuA:
undetectable
1gtfB-4hsuA:
undetectable
1gtfA-4hsuA:
7.64
1gtfB-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.95A 1gtfB-4hsuA:
undetectable
1gtfC-4hsuA:
undetectable
1gtfB-4hsuA:
7.64
1gtfC-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 1gtfC-4hsuA:
undetectable
1gtfD-4hsuA:
undetectable
1gtfC-4hsuA:
7.64
1gtfD-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.97A 1gtfD-4hsuA:
undetectable
1gtfE-4hsuA:
undetectable
1gtfD-4hsuA:
7.64
1gtfE-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 1gtfE-4hsuA:
undetectable
1gtfF-4hsuA:
undetectable
1gtfE-4hsuA:
7.64
1gtfF-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 1gtfF-4hsuA:
undetectable
1gtfG-4hsuA:
undetectable
1gtfF-4hsuA:
7.64
1gtfG-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.92A 1gtfG-4hsuA:
undetectable
1gtfH-4hsuA:
undetectable
1gtfG-4hsuA:
7.64
1gtfH-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 1gtfH-4hsuA:
undetectable
1gtfI-4hsuA:
undetectable
1gtfH-4hsuA:
7.64
1gtfI-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 1gtfI-4hsuA:
undetectable
1gtfJ-4hsuA:
undetectable
1gtfI-4hsuA:
7.64
1gtfJ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.95A 1gtfJ-4hsuA:
undetectable
1gtfK-4hsuA:
undetectable
1gtfJ-4hsuA:
7.64
1gtfK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 1gtfO-4hsuA:
undetectable
1gtfP-4hsuA:
undetectable
1gtfO-4hsuA:
7.64
1gtfP-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.97A 1gtfP-4hsuA:
undetectable
1gtfQ-4hsuA:
undetectable
1gtfP-4hsuA:
7.64
1gtfQ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 1gtfQ-4hsuA:
undetectable
1gtfR-4hsuA:
undetectable
1gtfQ-4hsuA:
7.64
1gtfR-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 1gtfR-4hsuA:
undetectable
1gtfS-4hsuA:
undetectable
1gtfR-4hsuA:
7.64
1gtfS-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 1gtfS-4hsuA:
undetectable
1gtfT-4hsuA:
undetectable
1gtfS-4hsuA:
7.64
1gtfT-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 1gtfT-4hsuA:
undetectable
1gtfU-4hsuA:
undetectable
1gtfT-4hsuA:
7.64
1gtfU-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 1gtfU-4hsuA:
undetectable
1gtfV-4hsuA:
undetectable
1gtfU-4hsuA:
7.64
1gtfV-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.97A 1gtfL-4hsuA:
undetectable
1gtfV-4hsuA:
undetectable
1gtfL-4hsuA:
7.64
1gtfV-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 7 GLY A 389
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
0.79A 1gtnA-4hsuA:
undetectable
1gtnK-4hsuA:
undetectable
1gtnA-4hsuA:
7.64
1gtnK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 1gtnB-4hsuA:
undetectable
1gtnC-4hsuA:
undetectable
1gtnB-4hsuA:
7.64
1gtnC-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 7 SER A 811
GLY A 389
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
0.85A 1gtnC-4hsuA:
undetectable
1gtnD-4hsuA:
undetectable
1gtnC-4hsuA:
7.64
1gtnD-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 6 SER A 811
GLY A 389
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
0.84A 1gtnD-4hsuA:
undetectable
1gtnE-4hsuA:
undetectable
1gtnD-4hsuA:
7.64
1gtnE-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 8 SER A 811
GLY A 389
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
0.82A 1gtnE-4hsuA:
undetectable
1gtnF-4hsuA:
undetectable
1gtnE-4hsuA:
7.64
1gtnF-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 7 SER A 811
GLY A 389
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
0.81A 1gtnF-4hsuA:
undetectable
1gtnG-4hsuA:
undetectable
1gtnF-4hsuA:
7.64
1gtnG-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.95A 1gtnG-4hsuA:
undetectable
1gtnH-4hsuA:
undetectable
1gtnG-4hsuA:
7.64
1gtnH-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.97A 1gtnH-4hsuA:
undetectable
1gtnI-4hsuA:
undetectable
1gtnH-4hsuA:
7.64
1gtnI-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 7 SER A 811
GLY A 389
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
0.82A 1gtnJ-4hsuA:
undetectable
1gtnK-4hsuA:
undetectable
1gtnJ-4hsuA:
7.64
1gtnK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.02A 1gtnL-4hsuA:
undetectable
1gtnM-4hsuA:
undetectable
1gtnL-4hsuA:
7.64
1gtnM-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.03A 1gtnM-4hsuA:
undetectable
1gtnN-4hsuA:
undetectable
1gtnM-4hsuA:
7.64
1gtnN-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.01A 1gtnN-4hsuA:
undetectable
1gtnO-4hsuA:
undetectable
1gtnN-4hsuA:
7.64
1gtnO-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.05A 1gtnR-4hsuA:
undetectable
1gtnS-4hsuA:
undetectable
1gtnR-4hsuA:
7.64
1gtnS-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.06A 1gtnS-4hsuA:
undetectable
1gtnT-4hsuA:
undetectable
1gtnS-4hsuA:
7.64
1gtnT-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 1gtnT-4hsuA:
undetectable
1gtnU-4hsuA:
undetectable
1gtnT-4hsuA:
7.64
1gtnU-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 1gtnU-4hsuA:
undetectable
1gtnV-4hsuA:
undetectable
1gtnU-4hsuA:
7.64
1gtnV-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 GLY A 776
ASN A 562
GLY A 655
ALA A 796
LEU A 629
None
1.10A 1jg4A-4hsuA:
undetectable
1jg4A-4hsuA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 TYR A 779
VAL A 554
ALA A 650
GLY A 657
LEU A 632
None
1.03A 1kiaC-4hsuA:
3.5
1kiaC-4hsuA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 TYR A 779
VAL A 554
ALA A 650
GLY A 657
LEU A 632
None
1.05A 1nbhB-4hsuA:
3.3
1nbhB-4hsuA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.94A 1utdA-4hsuA:
undetectable
1utdB-4hsuA:
undetectable
1utdA-4hsuA:
7.64
1utdB-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.95A 1utdC-4hsuA:
undetectable
1utdD-4hsuA:
undetectable
1utdC-4hsuA:
7.64
1utdD-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.95A 1utdD-4hsuA:
undetectable
1utdE-4hsuA:
undetectable
1utdD-4hsuA:
7.64
1utdE-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.94A 1utdE-4hsuA:
undetectable
1utdF-4hsuA:
undetectable
1utdE-4hsuA:
7.64
1utdF-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.93A 1utdG-4hsuA:
undetectable
1utdH-4hsuA:
undetectable
1utdG-4hsuA:
7.64
1utdH-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.93A 1utdH-4hsuA:
undetectable
1utdI-4hsuA:
undetectable
1utdH-4hsuA:
7.64
1utdI-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 1utdA-4hsuA:
undetectable
1utdK-4hsuA:
undetectable
1utdA-4hsuA:
7.64
1utdK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 1utdM-4hsuA:
undetectable
1utdN-4hsuA:
undetectable
1utdM-4hsuA:
7.64
1utdN-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.95A 1utdN-4hsuA:
undetectable
1utdO-4hsuA:
undetectable
1utdN-4hsuA:
7.64
1utdO-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.97A 1utdO-4hsuA:
undetectable
1utdP-4hsuA:
undetectable
1utdO-4hsuA:
7.64
1utdP-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.00A 1utdP-4hsuA:
undetectable
1utdQ-4hsuA:
undetectable
1utdP-4hsuA:
7.64
1utdQ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.00A 1utdQ-4hsuA:
undetectable
1utdR-4hsuA:
undetectable
1utdQ-4hsuA:
7.64
1utdR-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 1utdR-4hsuA:
undetectable
1utdS-4hsuA:
undetectable
1utdR-4hsuA:
7.64
1utdS-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 1utdS-4hsuA:
undetectable
1utdT-4hsuA:
undetectable
1utdS-4hsuA:
7.64
1utdT-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.00A 1utdT-4hsuA:
undetectable
1utdU-4hsuA:
undetectable
1utdT-4hsuA:
7.64
1utdU-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 1utdU-4hsuA:
undetectable
1utdV-4hsuA:
undetectable
1utdU-4hsuA:
7.64
1utdV-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
1.00A 1utdL-4hsuA:
undetectable
1utdV-4hsuA:
undetectable
1utdL-4hsuA:
7.64
1utdV-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 PHE A 404
LEU A 376
ALA A 820
ALA A 816
TYR A 809
None
1.00A 2fr3A-4hsuA:
undetectable
2fr3A-4hsuA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 LEU A 632
ILE A 786
VAL A 623
ILE A 819
PHE A 792
None
1.13A 2h42C-4hsuA:
undetectable
2h42C-4hsuA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 6 LEU A 376
GLN A 621
ILE A 406
PHE A 404
None
1.03A 2jn3A-4hsuA:
undetectable
2jn3A-4hsuA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 ASN A 445
LEU A 449
ALA A 448
LEU A 454
THR A 804
None
None
None
None
FAD  A 901 (-4.1A)
1.33A 2oaxF-4hsuA:
undetectable
2oaxF-4hsuA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 LEU A 449
MET A 458
LEU A 454
LEU A 575
THR A 804
None
None
None
None
FAD  A 901 (-4.1A)
1.44A 2oaxF-4hsuA:
undetectable
2oaxF-4hsuA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
3 / 3 PRO A 749
PHE A 753
LYS A 751
None
1.23A 3bjwG-4hsuA:
undetectable
3bjwG-4hsuA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 GLY A 391
GLY A 807
GLY A 794
GLY A 394
ASN A 562
FAD  A 901 (-3.6A)
None
FAD  A 901 (-3.2A)
None
None
0.96A 3elwA-4hsuA:
undetectable
3elwA-4hsuA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 THR A 409
LEU A 624
ALA A 390
ILE A 592
THR A 797
None
None
FAD  A 901 ( 4.9A)
None
None
1.27A 3qelA-4hsuA:
2.5
3qelB-4hsuA:
undetectable
3qelA-4hsuA:
18.90
3qelB-4hsuA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 4 LYS A 690
GLN A 534
ILE A 468
LEU A 737
None
1.30A 3qt0A-4hsuA:
undetectable
3qt0A-4hsuA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_A_ACHA323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 TYR A 545
ASN A 542
ILE A 438
TYR A 698
PHE A 680
None
None
FAD  A 901 (-3.9A)
None
None
1.50A 3rqwA-4hsuA:
0.0
3rqwB-4hsuA:
0.2
3rqwA-4hsuA:
18.17
3rqwB-4hsuA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_D_ACHD323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 TYR A 545
ASN A 542
ILE A 438
TYR A 698
PHE A 680
None
None
FAD  A 901 (-3.9A)
None
None
1.48A 3rqwD-4hsuA:
0.3
3rqwE-4hsuA:
0.4
3rqwD-4hsuA:
18.17
3rqwE-4hsuA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_E_ACHE323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 ILE A 438
TYR A 698
PHE A 680
TYR A 545
ASN A 542
FAD  A 901 (-3.9A)
None
None
None
None
1.49A 3rqwA-4hsuA:
0.0
3rqwE-4hsuA:
0.3
3rqwA-4hsuA:
18.17
3rqwE-4hsuA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_F_ACHF323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 TYR A 545
ASN A 542
ILE A 438
TYR A 698
PHE A 680
None
None
FAD  A 901 (-3.9A)
None
None
1.49A 3rqwF-4hsuA:
1.9
3rqwG-4hsuA:
1.9
3rqwF-4hsuA:
18.17
3rqwG-4hsuA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_H_ACHH323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 TYR A 545
ASN A 542
ILE A 438
TYR A 698
PHE A 680
None
None
FAD  A 901 (-3.9A)
None
None
1.49A 3rqwH-4hsuA:
0.1
3rqwI-4hsuA:
0.0
3rqwH-4hsuA:
18.17
3rqwI-4hsuA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 8 TYR A 545
ASN A 542
ILE A 438
TYR A 698
PHE A 680
None
None
FAD  A 901 (-3.9A)
None
None
1.49A 3rqwI-4hsuA:
undetectable
3rqwJ-4hsuA:
undetectable
3rqwI-4hsuA:
18.17
3rqwJ-4hsuA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 8 ILE A 781
ASP A 780
GLN A 503
GLY A 774
None
0.79A 4acaC-4hsuA:
undetectable
4acaC-4hsuA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 8 ILE A 781
ASP A 780
GLN A 503
GLY A 774
None
0.75A 4acbC-4hsuA:
undetectable
4acbC-4hsuA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
3 / 3 TRP A 422
TRP A 757
THR A 755
None
FAD  A 901 (-3.6A)
None
1.42A 4bboB-4hsuA:
undetectable
4bboB-4hsuA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_D_ACTD1113_0
(BLR5658 PROTEIN)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 4 TRP A 318
LEU A 367
LEU A 375
THR A 357
None
1.34A 4bboD-4hsuA:
undetectable
4bboD-4hsuA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 PHE A 670
PHE A 741
ILE A 468
GLY A 677
LEU A 709
None
1.04A 4e1gA-4hsuA:
undetectable
4e1gA-4hsuA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 PHE A 670
PHE A 741
ILE A 468
GLY A 677
LEU A 709
None
1.06A 4e1gB-4hsuA:
2.1
4e1gB-4hsuA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
3 / 3 GLN A 599
THR A 612
THR A 611
None
0.55A 4fu9A-4hsuA:
undetectable
4fu9A-4hsuA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
3 / 3 GLN A 599
THR A 612
THR A 611
None
0.52A 4fufA-4hsuA:
undetectable
4fufA-4hsuA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
3 / 3 LYS A 704
ARG A 669
TRP A 671
None
1.40A 4i90A-4hsuA:
undetectable
4i90A-4hsuA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 LEU A 136
GLU A  89
LEU A 340
ILE A 336
ILE A 335
None
1.21A 4j24C-4hsuA:
undetectable
4j24C-4hsuA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 LEU A 340
GLU A  89
LEU A 136
ILE A 335
ILE A 336
None
1.29A 4j24C-4hsuA:
undetectable
4j24C-4hsuA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 LEU A 136
GLU A  89
LEU A 340
ILE A 336
ILE A 335
None
1.23A 4j26B-4hsuA:
undetectable
4j26B-4hsuA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 LEU A 340
GLU A  89
LEU A 136
ILE A 335
ILE A 336
None
1.31A 4j26B-4hsuA:
undetectable
4j26B-4hsuA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
3 / 3 ASP A 506
LYS A 771
LEU A 654
None
1.07A 4ptjA-4hsuA:
undetectable
4ptjA-4hsuA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 GLY A 812
GLY A 794
SER A 811
LEU A 810
ALA A 396
None
FAD  A 901 (-3.2A)
None
None
None
0.86A 4uciA-4hsuA:
undetectable
4uciA-4hsuA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 GLY A 812
GLY A 794
SER A 811
LEU A 810
ALA A 396
None
FAD  A 901 (-3.2A)
None
None
None
0.86A 4uciB-4hsuA:
undetectable
4uciB-4hsuA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 GLY A 812
GLY A 794
SER A 811
LEU A 810
ALA A 396
None
FAD  A 901 (-3.2A)
None
None
None
0.86A 4uckA-4hsuA:
undetectable
4uckA-4hsuA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B
PUTATIVE
OXIDOREDUCTASE GLYR1

(Homo
sapiens;
Homo
sapiens)
4 / 5 LEU B 221
TYR A 809
LEU A 810
THR A 364
None
1.26A 4wozF-4hsuB:
undetectable
4wozH-4hsuB:
undetectable
4wozF-4hsuB:
16.45
4wozH-4hsuB:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 SER A 817
ALA A 816
LEU A 376
LEU A 375
ILE A 362
None
1.11A 4xumB-4hsuA:
undetectable
4xumB-4hsuA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 8 ALA A 793
GLY A 812
ALA A 397
GLY A 394
None
0.66A 4zjzA-4hsuA:
undetectable
4zjzA-4hsuA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 TYR A 698
HIS A 459
GLY A 677
GLY A 682
PHE A 461
None
1.13A 5d4uA-4hsuA:
2.8
5d4uA-4hsuA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eeuA-4hsuA:
undetectable
5eeuB-4hsuA:
undetectable
5eeuA-4hsuA:
7.64
5eeuB-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.96A 5eeuB-4hsuA:
undetectable
5eeuC-4hsuA:
undetectable
5eeuB-4hsuA:
7.64
5eeuC-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eeuC-4hsuA:
undetectable
5eeuD-4hsuA:
undetectable
5eeuC-4hsuA:
7.64
5eeuD-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eeuD-4hsuA:
undetectable
5eeuE-4hsuA:
undetectable
5eeuD-4hsuA:
7.64
5eeuE-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eeuE-4hsuA:
undetectable
5eeuF-4hsuA:
undetectable
5eeuE-4hsuA:
7.64
5eeuF-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eeuF-4hsuA:
undetectable
5eeuG-4hsuA:
undetectable
5eeuF-4hsuA:
7.64
5eeuG-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.92A 5eeuG-4hsuA:
undetectable
5eeuH-4hsuA:
undetectable
5eeuG-4hsuA:
7.64
5eeuH-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eeuH-4hsuA:
undetectable
5eeuI-4hsuA:
undetectable
5eeuH-4hsuA:
7.64
5eeuI-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 ALA A 396
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
1.05A 5eeuI-4hsuA:
undetectable
5eeuJ-4hsuA:
undetectable
5eeuI-4hsuA:
7.64
5eeuJ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.92A 5eeuI-4hsuA:
undetectable
5eeuJ-4hsuA:
undetectable
5eeuI-4hsuA:
7.64
5eeuJ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eeuJ-4hsuA:
undetectable
5eeuK-4hsuA:
undetectable
5eeuJ-4hsuA:
7.64
5eeuK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.92A 5eeuA-4hsuA:
undetectable
5eeuK-4hsuA:
undetectable
5eeuA-4hsuA:
7.64
5eeuK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5eeuN-4hsuA:
undetectable
5eeuO-4hsuA:
undetectable
5eeuN-4hsuA:
7.64
5eeuO-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eeuO-4hsuA:
undetectable
5eeuP-4hsuA:
undetectable
5eeuO-4hsuA:
7.64
5eeuP-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.97A 5eeuP-4hsuA:
undetectable
5eeuQ-4hsuA:
undetectable
5eeuP-4hsuA:
7.64
5eeuQ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eeuQ-4hsuA:
undetectable
5eeuR-4hsuA:
undetectable
5eeuQ-4hsuA:
7.64
5eeuR-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eeuR-4hsuA:
undetectable
5eeuS-4hsuA:
undetectable
5eeuR-4hsuA:
7.64
5eeuS-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eeuS-4hsuA:
undetectable
5eeuT-4hsuA:
undetectable
5eeuS-4hsuA:
7.64
5eeuT-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.95A 5eeuT-4hsuA:
undetectable
5eeuU-4hsuA:
undetectable
5eeuT-4hsuA:
7.64
5eeuU-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.96A 5eeuU-4hsuA:
undetectable
5eeuV-4hsuA:
undetectable
5eeuU-4hsuA:
7.64
5eeuV-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eevA-4hsuA:
undetectable
5eevB-4hsuA:
undetectable
5eevA-4hsuA:
7.64
5eevB-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.96A 5eevB-4hsuA:
undetectable
5eevC-4hsuA:
undetectable
5eevB-4hsuA:
7.64
5eevC-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eevC-4hsuA:
undetectable
5eevD-4hsuA:
undetectable
5eevC-4hsuA:
7.64
5eevD-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eevD-4hsuA:
undetectable
5eevE-4hsuA:
undetectable
5eevD-4hsuA:
7.64
5eevE-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eevE-4hsuA:
undetectable
5eevF-4hsuA:
undetectable
5eevE-4hsuA:
7.64
5eevF-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eevF-4hsuA:
undetectable
5eevG-4hsuA:
undetectable
5eevF-4hsuA:
7.64
5eevG-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.92A 5eevG-4hsuA:
undetectable
5eevH-4hsuA:
undetectable
5eevG-4hsuA:
7.64
5eevH-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eevH-4hsuA:
undetectable
5eevI-4hsuA:
undetectable
5eevH-4hsuA:
7.64
5eevI-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 ALA A 396
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
1.05A 5eevI-4hsuA:
undetectable
5eevJ-4hsuA:
undetectable
5eevI-4hsuA:
7.64
5eevJ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eevI-4hsuA:
undetectable
5eevJ-4hsuA:
undetectable
5eevI-4hsuA:
7.64
5eevJ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eevJ-4hsuA:
undetectable
5eevK-4hsuA:
undetectable
5eevJ-4hsuA:
7.64
5eevK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.92A 5eevA-4hsuA:
undetectable
5eevK-4hsuA:
undetectable
5eevA-4hsuA:
7.64
5eevK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5eevN-4hsuA:
undetectable
5eevO-4hsuA:
undetectable
5eevN-4hsuA:
7.64
5eevO-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eevO-4hsuA:
undetectable
5eevP-4hsuA:
undetectable
5eevO-4hsuA:
7.64
5eevP-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.97A 5eevP-4hsuA:
undetectable
5eevQ-4hsuA:
undetectable
5eevP-4hsuA:
7.64
5eevQ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5eevQ-4hsuA:
undetectable
5eevR-4hsuA:
undetectable
5eevQ-4hsuA:
7.64
5eevR-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eevR-4hsuA:
undetectable
5eevS-4hsuA:
undetectable
5eevR-4hsuA:
7.64
5eevS-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5eevS-4hsuA:
undetectable
5eevT-4hsuA:
undetectable
5eevS-4hsuA:
7.64
5eevT-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.95A 5eevT-4hsuA:
undetectable
5eevU-4hsuA:
undetectable
5eevT-4hsuA:
7.64
5eevU-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.96A 5eevU-4hsuA:
undetectable
5eevV-4hsuA:
undetectable
5eevU-4hsuA:
7.64
5eevV-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eewA-4hsuA:
undetectable
5eewB-4hsuA:
undetectable
5eewA-4hsuA:
7.64
5eewB-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.96A 5eewB-4hsuA:
undetectable
5eewC-4hsuA:
undetectable
5eewB-4hsuA:
7.64
5eewC-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eewC-4hsuA:
undetectable
5eewD-4hsuA:
undetectable
5eewC-4hsuA:
7.64
5eewD-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eewD-4hsuA:
undetectable
5eewE-4hsuA:
undetectable
5eewD-4hsuA:
7.64
5eewE-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eewE-4hsuA:
undetectable
5eewF-4hsuA:
undetectable
5eewE-4hsuA:
7.64
5eewF-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eewF-4hsuA:
undetectable
5eewG-4hsuA:
undetectable
5eewF-4hsuA:
7.64
5eewG-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.92A 5eewG-4hsuA:
undetectable
5eewH-4hsuA:
undetectable
5eewG-4hsuA:
7.64
5eewH-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eewH-4hsuA:
undetectable
5eewI-4hsuA:
undetectable
5eewH-4hsuA:
7.64
5eewI-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 ALA A 396
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
1.05A 5eewI-4hsuA:
undetectable
5eewJ-4hsuA:
undetectable
5eewI-4hsuA:
7.64
5eewJ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eewI-4hsuA:
undetectable
5eewJ-4hsuA:
undetectable
5eewI-4hsuA:
7.64
5eewJ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eewJ-4hsuA:
undetectable
5eewK-4hsuA:
undetectable
5eewJ-4hsuA:
7.64
5eewK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.93A 5eewA-4hsuA:
undetectable
5eewK-4hsuA:
undetectable
5eewA-4hsuA:
7.64
5eewK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5eewN-4hsuA:
undetectable
5eewO-4hsuA:
undetectable
5eewN-4hsuA:
7.64
5eewO-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eewO-4hsuA:
undetectable
5eewP-4hsuA:
undetectable
5eewO-4hsuA:
7.64
5eewP-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eewP-4hsuA:
undetectable
5eewQ-4hsuA:
undetectable
5eewP-4hsuA:
7.64
5eewQ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5eewQ-4hsuA:
undetectable
5eewR-4hsuA:
undetectable
5eewQ-4hsuA:
7.64
5eewR-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eewR-4hsuA:
undetectable
5eewS-4hsuA:
undetectable
5eewR-4hsuA:
7.64
5eewS-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5eewS-4hsuA:
undetectable
5eewT-4hsuA:
undetectable
5eewS-4hsuA:
7.64
5eewT-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.95A 5eewT-4hsuA:
undetectable
5eewU-4hsuA:
undetectable
5eewT-4hsuA:
7.64
5eewU-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.96A 5eewU-4hsuA:
undetectable
5eewV-4hsuA:
undetectable
5eewU-4hsuA:
7.64
5eewV-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eexA-4hsuA:
undetectable
5eexB-4hsuA:
undetectable
5eexA-4hsuA:
7.64
5eexB-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.96A 5eexB-4hsuA:
undetectable
5eexC-4hsuA:
undetectable
5eexB-4hsuA:
7.64
5eexC-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eexC-4hsuA:
undetectable
5eexD-4hsuA:
undetectable
5eexC-4hsuA:
7.64
5eexD-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eexD-4hsuA:
undetectable
5eexE-4hsuA:
undetectable
5eexD-4hsuA:
7.64
5eexE-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eexE-4hsuA:
undetectable
5eexF-4hsuA:
undetectable
5eexE-4hsuA:
7.64
5eexF-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eexF-4hsuA:
undetectable
5eexG-4hsuA:
undetectable
5eexF-4hsuA:
7.64
5eexG-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.92A 5eexG-4hsuA:
undetectable
5eexH-4hsuA:
undetectable
5eexG-4hsuA:
7.64
5eexH-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eexH-4hsuA:
undetectable
5eexI-4hsuA:
undetectable
5eexH-4hsuA:
7.64
5eexI-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eexI-4hsuA:
undetectable
5eexJ-4hsuA:
undetectable
5eexI-4hsuA:
7.64
5eexJ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eexJ-4hsuA:
undetectable
5eexK-4hsuA:
undetectable
5eexJ-4hsuA:
7.64
5eexK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.93A 5eexA-4hsuA:
undetectable
5eexK-4hsuA:
undetectable
5eexA-4hsuA:
7.64
5eexK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.00A 5eexN-4hsuA:
undetectable
5eexO-4hsuA:
undetectable
5eexN-4hsuA:
7.64
5eexO-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eexO-4hsuA:
undetectable
5eexP-4hsuA:
undetectable
5eexO-4hsuA:
7.64
5eexP-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.97A 5eexP-4hsuA:
undetectable
5eexQ-4hsuA:
undetectable
5eexP-4hsuA:
7.64
5eexQ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5eexQ-4hsuA:
undetectable
5eexR-4hsuA:
undetectable
5eexQ-4hsuA:
7.64
5eexR-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eexR-4hsuA:
undetectable
5eexS-4hsuA:
undetectable
5eexR-4hsuA:
7.64
5eexS-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5eexS-4hsuA:
undetectable
5eexT-4hsuA:
undetectable
5eexS-4hsuA:
7.64
5eexT-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.95A 5eexT-4hsuA:
undetectable
5eexU-4hsuA:
undetectable
5eexT-4hsuA:
7.64
5eexU-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.96A 5eexU-4hsuA:
undetectable
5eexV-4hsuA:
undetectable
5eexU-4hsuA:
7.64
5eexV-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eeyA-4hsuA:
undetectable
5eeyB-4hsuA:
undetectable
5eeyA-4hsuA:
7.64
5eeyB-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.96A 5eeyB-4hsuA:
undetectable
5eeyC-4hsuA:
undetectable
5eeyB-4hsuA:
7.64
5eeyC-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eeyC-4hsuA:
undetectable
5eeyD-4hsuA:
undetectable
5eeyC-4hsuA:
7.64
5eeyD-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eeyD-4hsuA:
undetectable
5eeyE-4hsuA:
undetectable
5eeyD-4hsuA:
7.64
5eeyE-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eeyE-4hsuA:
undetectable
5eeyF-4hsuA:
undetectable
5eeyE-4hsuA:
7.64
5eeyF-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eeyF-4hsuA:
undetectable
5eeyG-4hsuA:
undetectable
5eeyF-4hsuA:
7.64
5eeyG-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.92A 5eeyG-4hsuA:
undetectable
5eeyH-4hsuA:
undetectable
5eeyG-4hsuA:
7.64
5eeyH-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.95A 5eeyH-4hsuA:
undetectable
5eeyI-4hsuA:
undetectable
5eeyH-4hsuA:
7.64
5eeyI-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eeyI-4hsuA:
undetectable
5eeyJ-4hsuA:
undetectable
5eeyI-4hsuA:
7.64
5eeyJ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eeyJ-4hsuA:
undetectable
5eeyK-4hsuA:
undetectable
5eeyJ-4hsuA:
7.64
5eeyK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.93A 5eeyA-4hsuA:
undetectable
5eeyK-4hsuA:
undetectable
5eeyA-4hsuA:
7.64
5eeyK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.00A 5eeyN-4hsuA:
undetectable
5eeyO-4hsuA:
undetectable
5eeyN-4hsuA:
7.64
5eeyO-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eeyO-4hsuA:
undetectable
5eeyP-4hsuA:
undetectable
5eeyO-4hsuA:
7.64
5eeyP-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eeyP-4hsuA:
undetectable
5eeyQ-4hsuA:
undetectable
5eeyP-4hsuA:
7.64
5eeyQ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5eeyQ-4hsuA:
undetectable
5eeyR-4hsuA:
undetectable
5eeyQ-4hsuA:
7.64
5eeyR-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eeyR-4hsuA:
undetectable
5eeyS-4hsuA:
undetectable
5eeyR-4hsuA:
7.64
5eeyS-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5eeyS-4hsuA:
undetectable
5eeyT-4hsuA:
undetectable
5eeyS-4hsuA:
7.64
5eeyT-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.95A 5eeyT-4hsuA:
undetectable
5eeyU-4hsuA:
undetectable
5eeyT-4hsuA:
7.64
5eeyU-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.96A 5eeyU-4hsuA:
undetectable
5eeyV-4hsuA:
undetectable
5eeyU-4hsuA:
7.64
5eeyV-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eezA-4hsuA:
undetectable
5eezB-4hsuA:
undetectable
5eezA-4hsuA:
7.64
5eezB-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.96A 5eezB-4hsuA:
undetectable
5eezC-4hsuA:
undetectable
5eezB-4hsuA:
7.64
5eezC-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eezC-4hsuA:
undetectable
5eezD-4hsuA:
undetectable
5eezC-4hsuA:
7.64
5eezD-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eezD-4hsuA:
undetectable
5eezE-4hsuA:
undetectable
5eezD-4hsuA:
7.64
5eezE-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eezE-4hsuA:
undetectable
5eezF-4hsuA:
undetectable
5eezE-4hsuA:
7.64
5eezF-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eezF-4hsuA:
undetectable
5eezG-4hsuA:
undetectable
5eezF-4hsuA:
7.64
5eezG-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eezG-4hsuA:
undetectable
5eezH-4hsuA:
undetectable
5eezG-4hsuA:
7.64
5eezH-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.95A 5eezH-4hsuA:
undetectable
5eezI-4hsuA:
undetectable
5eezH-4hsuA:
7.64
5eezI-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5eezI-4hsuA:
undetectable
5eezJ-4hsuA:
undetectable
5eezI-4hsuA:
7.64
5eezJ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5eezJ-4hsuA:
undetectable
5eezK-4hsuA:
undetectable
5eezJ-4hsuA:
7.64
5eezK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.93A 5eezA-4hsuA:
undetectable
5eezK-4hsuA:
undetectable
5eezA-4hsuA:
7.64
5eezK-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.00A 5eezN-4hsuA:
undetectable
5eezO-4hsuA:
undetectable
5eezN-4hsuA:
7.64
5eezO-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eezO-4hsuA:
undetectable
5eezP-4hsuA:
undetectable
5eezO-4hsuA:
7.64
5eezP-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eezP-4hsuA:
undetectable
5eezQ-4hsuA:
undetectable
5eezP-4hsuA:
7.64
5eezQ-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5eezQ-4hsuA:
undetectable
5eezR-4hsuA:
undetectable
5eezQ-4hsuA:
7.64
5eezR-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5eezR-4hsuA:
undetectable
5eezS-4hsuA:
undetectable
5eezR-4hsuA:
7.64
5eezS-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5eezS-4hsuA:
undetectable
5eezT-4hsuA:
undetectable
5eezS-4hsuA:
7.64
5eezT-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.95A 5eezT-4hsuA:
undetectable
5eezU-4hsuA:
undetectable
5eezT-4hsuA:
7.64
5eezU-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.96A 5eezU-4hsuA:
undetectable
5eezV-4hsuA:
undetectable
5eezU-4hsuA:
7.64
5eezV-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef0A-4hsuA:
undetectable
5ef0B-4hsuA:
undetectable
5ef0A-4hsuA:
7.64
5ef0B-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.96A 5ef0B-4hsuA:
undetectable
5ef0C-4hsuA:
undetectable
5ef0B-4hsuA:
7.64
5ef0C-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5ef0C-4hsuA:
undetectable
5ef0D-4hsuA:
undetectable
5ef0C-4hsuA:
7.64
5ef0D-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef0D-4hsuA:
undetectable
5ef0E-4hsuA:
undetectable
5ef0D-4hsuA:
7.64
5ef0E-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef0E-4hsuA:
undetectable
5ef0F-4hsuA:
undetectable
5ef0E-4hsuA:
7.64
5ef0F-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef0F-4hsuA:
undetectable
5ef0G-4hsuA:
undetectable
5ef0F-4hsuA:
7.64
5ef0G-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5ef0G-4hsuA:
undetectable
5ef0H-4hsuA:
undetectable
5ef0G-4hsuA:
7.64
5ef0H-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef0H-4hsuA:
undetectable
5ef0I-4hsuA:
undetectable
5ef0H-4hsuA:
7.64
5ef0I-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5ef0I-4hsuA:
undetectable
5ef0J-4hsuA:
undetectable
5ef0I-4hsuA:
7.64
5ef0J-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef0J-4hsuA:
undetectable
5ef0K-4hsuA:
undetectable
5ef0J-4hsuA:
7.64
5ef0K-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.92A 5ef0A-4hsuA:
undetectable
5ef0K-4hsuA:
undetectable
5ef0A-4hsuA:
7.64
5ef0K-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.00A 5ef0N-4hsuA:
undetectable
5ef0O-4hsuA:
undetectable
5ef0N-4hsuA:
7.64
5ef0O-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5ef0O-4hsuA:
undetectable
5ef0P-4hsuA:
undetectable
5ef0O-4hsuA:
7.64
5ef0P-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5ef0P-4hsuA:
undetectable
5ef0Q-4hsuA:
undetectable
5ef0P-4hsuA:
7.64
5ef0Q-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5ef0Q-4hsuA:
undetectable
5ef0R-4hsuA:
undetectable
5ef0Q-4hsuA:
7.64
5ef0R-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5ef0R-4hsuA:
undetectable
5ef0S-4hsuA:
undetectable
5ef0R-4hsuA:
7.64
5ef0S-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5ef0S-4hsuA:
undetectable
5ef0T-4hsuA:
undetectable
5ef0S-4hsuA:
7.64
5ef0T-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.95A 5ef0T-4hsuA:
undetectable
5ef0U-4hsuA:
undetectable
5ef0T-4hsuA:
7.64
5ef0U-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.97A 5ef0U-4hsuA:
undetectable
5ef0V-4hsuA:
undetectable
5ef0U-4hsuA:
7.64
5ef0V-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef1A-4hsuA:
undetectable
5ef1B-4hsuA:
undetectable
5ef1A-4hsuA:
7.64
5ef1B-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.96A 5ef1B-4hsuA:
undetectable
5ef1C-4hsuA:
undetectable
5ef1B-4hsuA:
7.64
5ef1C-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5ef1C-4hsuA:
undetectable
5ef1D-4hsuA:
undetectable
5ef1C-4hsuA:
7.64
5ef1D-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef1D-4hsuA:
undetectable
5ef1E-4hsuA:
undetectable
5ef1D-4hsuA:
7.64
5ef1E-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef1E-4hsuA:
undetectable
5ef1F-4hsuA:
undetectable
5ef1E-4hsuA:
7.64
5ef1F-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef1F-4hsuA:
undetectable
5ef1G-4hsuA:
undetectable
5ef1F-4hsuA:
7.64
5ef1G-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5ef1G-4hsuA:
undetectable
5ef1H-4hsuA:
undetectable
5ef1G-4hsuA:
7.64
5ef1H-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.95A 5ef1H-4hsuA:
undetectable
5ef1I-4hsuA:
undetectable
5ef1H-4hsuA:
7.64
5ef1I-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5ef1I-4hsuA:
undetectable
5ef1J-4hsuA:
undetectable
5ef1I-4hsuA:
7.64
5ef1J-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef1J-4hsuA:
undetectable
5ef1K-4hsuA:
undetectable
5ef1J-4hsuA:
7.64
5ef1K-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.92A 5ef1A-4hsuA:
undetectable
5ef1K-4hsuA:
undetectable
5ef1A-4hsuA:
7.64
5ef1K-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.00A 5ef1N-4hsuA:
undetectable
5ef1O-4hsuA:
undetectable
5ef1N-4hsuA:
7.64
5ef1O-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5ef1O-4hsuA:
undetectable
5ef1P-4hsuA:
undetectable
5ef1O-4hsuA:
7.64
5ef1P-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5ef1P-4hsuA:
undetectable
5ef1Q-4hsuA:
undetectable
5ef1P-4hsuA:
7.64
5ef1Q-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5ef1Q-4hsuA:
undetectable
5ef1R-4hsuA:
undetectable
5ef1Q-4hsuA:
7.64
5ef1R-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5ef1R-4hsuA:
undetectable
5ef1S-4hsuA:
undetectable
5ef1R-4hsuA:
7.64
5ef1S-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5ef1S-4hsuA:
undetectable
5ef1T-4hsuA:
undetectable
5ef1S-4hsuA:
7.64
5ef1T-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.95A 5ef1T-4hsuA:
undetectable
5ef1U-4hsuA:
undetectable
5ef1T-4hsuA:
7.64
5ef1U-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.97A 5ef1U-4hsuA:
undetectable
5ef1V-4hsuA:
undetectable
5ef1U-4hsuA:
7.64
5ef1V-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef2A-4hsuA:
undetectable
5ef2B-4hsuA:
undetectable
5ef2A-4hsuA:
7.64
5ef2B-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.95A 5ef2B-4hsuA:
undetectable
5ef2C-4hsuA:
undetectable
5ef2B-4hsuA:
7.64
5ef2C-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5ef2C-4hsuA:
undetectable
5ef2D-4hsuA:
undetectable
5ef2C-4hsuA:
7.64
5ef2D-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef2D-4hsuA:
undetectable
5ef2E-4hsuA:
undetectable
5ef2D-4hsuA:
7.64
5ef2E-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef2E-4hsuA:
undetectable
5ef2F-4hsuA:
undetectable
5ef2E-4hsuA:
7.64
5ef2F-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef2F-4hsuA:
undetectable
5ef2G-4hsuA:
undetectable
5ef2F-4hsuA:
7.64
5ef2G-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5ef2G-4hsuA:
undetectable
5ef2H-4hsuA:
undetectable
5ef2G-4hsuA:
7.64
5ef2H-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.95A 5ef2H-4hsuA:
undetectable
5ef2I-4hsuA:
undetectable
5ef2H-4hsuA:
7.64
5ef2I-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5ef2I-4hsuA:
undetectable
5ef2J-4hsuA:
undetectable
5ef2I-4hsuA:
7.64
5ef2J-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef2J-4hsuA:
undetectable
5ef2K-4hsuA:
undetectable
5ef2J-4hsuA:
7.64
5ef2K-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.93A 5ef2A-4hsuA:
undetectable
5ef2K-4hsuA:
undetectable
5ef2A-4hsuA:
7.64
5ef2K-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.00A 5ef2N-4hsuA:
undetectable
5ef2O-4hsuA:
undetectable
5ef2N-4hsuA:
7.64
5ef2O-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5ef2O-4hsuA:
undetectable
5ef2P-4hsuA:
undetectable
5ef2O-4hsuA:
7.64
5ef2P-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5ef2P-4hsuA:
undetectable
5ef2Q-4hsuA:
undetectable
5ef2P-4hsuA:
7.64
5ef2Q-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5ef2Q-4hsuA:
undetectable
5ef2R-4hsuA:
undetectable
5ef2Q-4hsuA:
7.64
5ef2R-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5ef2R-4hsuA:
undetectable
5ef2S-4hsuA:
undetectable
5ef2R-4hsuA:
7.64
5ef2S-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5ef2S-4hsuA:
undetectable
5ef2T-4hsuA:
undetectable
5ef2S-4hsuA:
7.64
5ef2T-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.95A 5ef2T-4hsuA:
undetectable
5ef2U-4hsuA:
undetectable
5ef2T-4hsuA:
7.64
5ef2U-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.96A 5ef2U-4hsuA:
undetectable
5ef2V-4hsuA:
undetectable
5ef2U-4hsuA:
7.64
5ef2V-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef3A-4hsuA:
undetectable
5ef3B-4hsuA:
undetectable
5ef3A-4hsuA:
7.64
5ef3B-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.95A 5ef3B-4hsuA:
undetectable
5ef3C-4hsuA:
undetectable
5ef3B-4hsuA:
7.64
5ef3C-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5ef3C-4hsuA:
undetectable
5ef3D-4hsuA:
undetectable
5ef3C-4hsuA:
7.64
5ef3D-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef3D-4hsuA:
undetectable
5ef3E-4hsuA:
undetectable
5ef3D-4hsuA:
7.64
5ef3E-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef3E-4hsuA:
undetectable
5ef3F-4hsuA:
undetectable
5ef3E-4hsuA:
7.64
5ef3F-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef3F-4hsuA:
undetectable
5ef3G-4hsuA:
undetectable
5ef3F-4hsuA:
7.64
5ef3G-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5ef3G-4hsuA:
undetectable
5ef3H-4hsuA:
undetectable
5ef3G-4hsuA:
7.64
5ef3H-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef3H-4hsuA:
undetectable
5ef3I-4hsuA:
undetectable
5ef3H-4hsuA:
7.64
5ef3I-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 11 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.93A 5ef3I-4hsuA:
undetectable
5ef3J-4hsuA:
undetectable
5ef3I-4hsuA:
7.64
5ef3J-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 SER A 811
GLY A 389
ALA A 397
THR A 626
ILE A 387
None
FAD  A 901 (-3.3A)
None
None
None
0.94A 5ef3J-4hsuA:
undetectable
5ef3K-4hsuA:
undetectable
5ef3J-4hsuA:
7.64
5ef3K-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.92A 5ef3A-4hsuA:
undetectable
5ef3K-4hsuA:
undetectable
5ef3A-4hsuA:
7.64
5ef3K-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.00A 5ef3N-4hsuA:
undetectable
5ef3O-4hsuA:
undetectable
5ef3N-4hsuA:
7.64
5ef3O-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5ef3O-4hsuA:
undetectable
5ef3P-4hsuA:
undetectable
5ef3O-4hsuA:
7.64
5ef3P-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.98A 5ef3P-4hsuA:
undetectable
5ef3Q-4hsuA:
undetectable
5ef3P-4hsuA:
7.64
5ef3Q-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 9 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5ef3Q-4hsuA:
undetectable
5ef3R-4hsuA:
undetectable
5ef3Q-4hsuA:
7.64
5ef3R-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.99A 5ef3R-4hsuA:
undetectable
5ef3S-4hsuA:
undetectable
5ef3R-4hsuA:
7.64
5ef3S-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
1.00A 5ef3S-4hsuA:
undetectable
5ef3T-4hsuA:
undetectable
5ef3S-4hsuA:
7.64
5ef3T-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.95A 5ef3T-4hsuA:
undetectable
5ef3U-4hsuA:
undetectable
5ef3T-4hsuA:
7.64
5ef3U-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 10 GLY A 389
ALA A 397
THR A 626
ILE A 387
SER A 811
FAD  A 901 (-3.3A)
None
None
None
None
0.97A 5ef3U-4hsuA:
undetectable
5ef3V-4hsuA:
undetectable
5ef3U-4hsuA:
7.64
5ef3V-4hsuA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 THR A 409
LEU A 624
ALA A 390
ILE A 592
THR A 797
None
None
FAD  A 901 ( 4.9A)
None
None
1.29A 5ewjC-4hsuA:
undetectable
5ewjD-4hsuA:
2.1
5ewjC-4hsuA:
19.35
5ewjD-4hsuA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSE_C_HQEC1583_1
(UREASE SUBUNIT ALPHA)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 5 ILE A 335
ARG A 342
CYH A 345
GLU A 348
None
1.42A 5fseC-4hsuA:
undetectable
5fseC-4hsuA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 4 GLN A 141
THR A 143
THR A 160
LEU A 153
None
1.46A 5m5kA-4hsuA:
2.9
5m5kA-4hsuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 4 GLN A 141
THR A 143
THR A 160
LEU A 153
None
1.48A 5m5kC-4hsuA:
3.1
5m5kC-4hsuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 4 GLN A 141
THR A 143
THR A 160
LEU A 153
None
1.45A 5m66B-4hsuA:
2.8
5m66B-4hsuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
3 / 3 LYS A 115
TRP A 117
SER A 119
None
1.38A 5nwwA-4hsuA:
undetectable
5nwwA-4hsuA:
3.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 8 ILE A 786
ILE A 819
ALA A 793
THR A 626
None
0.68A 5og9A-4hsuA:
undetectable
5og9A-4hsuA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 TYR A 579
ILE A 582
LEU A 586
GLY A 807
ALA A 808
None
None
None
None
FAD  A 901 (-3.2A)
1.18A 5zwrA-4hsuA:
undetectable
5zwrA-4hsuA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_2
(-)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
4 / 4 GLN A 141
THR A 143
THR A 160
LEU A 153
None
1.42A 6f3mB-4hsuA:
2.9
6f3mB-4hsuA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo
sapiens)
5 / 12 ILE A 388
GLY A 389
GLY A 391
ALA A 396
VAL A 598
FAD  A 901 (-4.8A)
FAD  A 901 (-3.3A)
FAD  A 901 (-3.6A)
None
FAD  A 901 (-4.2A)
0.79A 6iftA-4hsuA:
2.9
6iftA-4hsuA:
17.51