SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4htf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_W_CHDW4060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 7	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.89A	1v54N-4htfB: undetectable 1v54W-4htfB: undetectable	1v54N-4htfB: 18.97 1v54W-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V55_J_CHDJ3060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 7	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.87A	1v55A-4htfB: undetectable 1v55J-4htfB: undetectable	1v55A-4htfB: 18.97 1v55J-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA3_A_STRA1001_2 (MINERALOCORTICOID RECEPTOR)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 4	LEU B 139 LEU B 147 SER B 146 LEU B 117	None	1.06A	1ya3A-4htfB: undetectable	1ya3A-4htfB: 21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_G_BEZG3385_0 (CES1 PROTEIN)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	3 / 3	SER B 146 VAL B 48 LEU B 115	None	0.72A	1yajG-4htfB: undetectable	1yajG-4htfB: 19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C12_C_SPMC1434_1 (NITROALKANE OXIDASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	LEU B 132 LEU B 117 SER B 146 LEU B 145 VAL B 144	None	1.10A	2c12C-4htfB: undetectable	2c12C-4htfB: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C12_F_SPMF1433_1 (NITROALKANE OXIDASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 11	LEU B 132 ALA B 51 LEU B 117 SER B 146 LEU B 145	None	1.33A	2c12F-4htfB: undetectable	2c12F-4htfB: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIJ_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 8	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.89A	2eijN-4htfB: undetectable 2eijW-4htfB: undetectable	2eijN-4htfB: 18.97 2eijW-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIK_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 8	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.90A	2eikN-4htfB: undetectable 2eikW-4htfB: undetectable	2eikN-4htfB: 18.97 2eikW-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 8	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.91A	2eilN-4htfB: undetectable 2eilW-4htfB: undetectable	2eilN-4htfB: 18.97 2eilW-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_A_SAMA301_0 (YCGJ)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 THR B 58 ASP B 73 ALA B 102	SAM B 301 (-3.5A) SAM B 301 (-3.4A) None SAM B 301 (-3.1A) SAM B 301 (-3.7A)	0.75A	2gluA-4htfB: 18.5	2gluA-4htfB: 24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_B_SAMB300_0 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 GLY B 56 LEU B 74 VAL B 121	SAM B 301 (-3.5A) SAM B 301 (-3.4A) None SAM B 301 (-4.2A) SAM B 301 ( 4.3A)	0.76A	2oxtB-4htfB: 8.5	2oxtB-4htfB: 21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_D_SAMD300_0 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	ASP B 50 GLY B 52 GLY B 54 LEU B 74 VAL B 121	SAM B 301 ( 4.7A) SAM B 301 (-3.5A) SAM B 301 (-3.4A) SAM B 301 (-4.2A) SAM B 301 ( 4.3A)	0.65A	2oxtD-4htfB: 8.5	2oxtD-4htfB: 21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABL_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 8	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.91A	3ablN-4htfB: undetectable 3ablW-4htfB: undetectable	3ablN-4htfB: 18.97 3ablW-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG3_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 7	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.91A	3ag3A-4htfB: undetectable 3ag3J-4htfB: undetectable	3ag3A-4htfB: 18.97 3ag3J-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_W_CHDW1059_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 8	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.90A	3asnN-4htfB: undetectable 3asnW-4htfB: undetectable	3asnN-4htfB: 18.97 3asnW-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G88_A_SAMA303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 11	GLY B 52 GLY B 54 ASP B 73 ALA B 102 ALA B 120	SAM B 301 (-3.5A) SAM B 301 (-3.4A) SAM B 301 (-3.1A) SAM B 301 (-3.7A) SAM B 301 (-4.0A)	0.75A	3g88A-4htfB: 13.4	3g88A-4htfB: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G88_B_SAMB303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 11	GLY B 52 GLY B 54 ASP B 73 ALA B 102 ALA B 120	SAM B 301 (-3.5A) SAM B 301 (-3.4A) SAM B 301 (-3.1A) SAM B 301 (-3.7A) SAM B 301 (-4.0A)	0.74A	3g88B-4htfB: 13.5	3g88B-4htfB: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G89_A_SAMA303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 ASP B 73 ALA B 102 ALA B 120	SAM B 301 (-3.5A) SAM B 301 (-3.4A) SAM B 301 (-3.1A) SAM B 301 (-3.7A) SAM B 301 (-4.0A)	0.68A	3g89A-4htfB: 13.5	3g89A-4htfB: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G89_B_SAMB303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 11	GLY B 52 GLY B 54 ASP B 73 ALA B 101 ALA B 120	SAM B 301 (-3.5A) SAM B 301 (-3.4A) SAM B 301 (-3.1A) SAM B 301 (-4.2A) SAM B 301 (-4.0A)	0.96A	3g89B-4htfB: 13.4	3g89B-4htfB: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G89_B_SAMB303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 11	GLY B 52 GLY B 54 ASP B 73 ALA B 102 ALA B 120	SAM B 301 (-3.5A) SAM B 301 (-3.4A) SAM B 301 (-3.1A) SAM B 301 (-3.7A) SAM B 301 (-4.0A)	0.66A	3g89B-4htfB: 13.4	3g89B-4htfB: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8B_A_SAMA303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 ASP B 73 ALA B 101 ALA B 120	SAM B 301 (-3.5A) SAM B 301 (-3.4A) SAM B 301 (-3.1A) SAM B 301 (-4.2A) SAM B 301 (-4.0A)	0.92A	3g8bA-4htfB: 13.5	3g8bA-4htfB: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8B_A_SAMA303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 ASP B 73 ALA B 102 ALA B 120	SAM B 301 (-3.5A) SAM B 301 (-3.4A) SAM B 301 (-3.1A) SAM B 301 (-3.7A) SAM B 301 (-4.0A)	0.68A	3g8bA-4htfB: 13.5	3g8bA-4htfB: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8B_B_SAMB303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 ASP B 73 ALA B 101 ALA B 120	SAM B 301 (-3.5A) SAM B 301 (-3.4A) SAM B 301 (-3.1A) SAM B 301 (-4.2A) SAM B 301 (-4.0A)	0.93A	3g8bB-4htfB: 12.3	3g8bB-4htfB: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8B_B_SAMB303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 ASP B 73 ALA B 102 ALA B 120	SAM B 301 (-3.5A) SAM B 301 (-3.4A) SAM B 301 (-3.1A) SAM B 301 (-3.7A) SAM B 301 (-4.0A)	0.69A	3g8bB-4htfB: 12.3	3g8bB-4htfB: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LCV_B_SAMB301_1 (SISOMICIN-GENTAMICIN RESISTANCE METHYLASE SGM)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	3 / 3	ARG B 26 ASP B 73 GLN B 103	SO4 B 302 ( 4.1A) SAM B 301 (-3.1A) SAM B 301 (-3.3A)	0.86A	3lcvB-4htfB: 10.0	3lcvB-4htfB: 24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FR0_A_SAMA401_0 (ARSENIC METHYLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 56 GLY B 53 LEU B 117 ILE B 60 GLU B 64	None SAM B 301 (-3.8A) None None None	1.12A	4fr0A-4htfB: 14.9	4fr0A-4htfB: 22.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HTF_A_ACTA303_0 (S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	3 / 3	TYR B 150 HIS B 158 ARG B 246	None	0.14A	4htfA-4htfB: 37.9	4htfA-4htfB: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HTF_A_SAMA301_0 (S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	12 / 12	ARG B 26 GLY B 52 GLY B 53 GLY B 54 LEU B 74 SER B 75 ALA B 102 GLN B 103 HIS B 119 VAL B 121 TRP B 124 VAL B 125	SO4 B 302 ( 4.1A) SAM B 301 (-3.5A) SAM B 301 (-3.8A) SAM B 301 (-3.4A) SAM B 301 (-4.2A) SAM B 301 (-4.7A) SAM B 301 (-3.7A) SAM B 301 (-3.3A) None SAM B 301 ( 4.3A) None None	0.27A	4htfA-4htfB: 37.9	4htfA-4htfB: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HTF_A_SAMA301_0 (S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	8 / 12	ARG B 26 GLY B 53 LEU B 74 SER B 75 GLN B 103 VAL B 121 TRP B 124 VAL B 125	SO4 B 302 ( 4.1A) SAM B 301 (-3.8A) SAM B 301 (-4.2A) SAM B 301 (-4.7A) SAM B 301 (-3.3A) SAM B 301 ( 4.3A) None None	1.08A	4htfA-4htfB: 37.9	4htfA-4htfB: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HTF_A_SAMA301_0 (S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	8 / 12	ARG B 26 GLY B 54 LEU B 74 ALA B 102 GLN B 103 VAL B 121 TRP B 124 VAL B 125	SO4 B 302 ( 4.1A) SAM B 301 (-3.4A) SAM B 301 (-4.2A) SAM B 301 (-3.7A) SAM B 301 (-3.3A) SAM B 301 ( 4.3A) None None	0.94A	4htfA-4htfB: 37.9	4htfA-4htfB: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HTF_B_SAMB301_0 (S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	12 / 12	ARG B 26 GLY B 52 GLY B 53 GLY B 54 LEU B 74 SER B 75 ALA B 102 GLN B 103 HIS B 119 VAL B 121 TRP B 124 VAL B 125	SO4 B 302 ( 4.1A) SAM B 301 (-3.5A) SAM B 301 (-3.8A) SAM B 301 (-3.4A) SAM B 301 (-4.2A) SAM B 301 (-4.7A) SAM B 301 (-3.7A) SAM B 301 (-3.3A) None SAM B 301 ( 4.3A) None None	0.00A	4htfB-4htfB: 43.2	4htfB-4htfB: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_A_SAMA900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 LEU B 74 SER B 75 ALA B 102	SAM B 301 (-3.5A) SAM B 301 (-3.4A) SAM B 301 (-4.2A) SAM B 301 (-4.7A) SAM B 301 (-3.7A)	0.69A	4krhA-4htfB: 12.3	4krhA-4htfB: 21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_B_SAMB900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 LEU B 74 SER B 75 ALA B 102	SAM B 301 (-3.5A) SAM B 301 (-3.4A) SAM B 301 (-4.2A) SAM B 301 (-4.7A) SAM B 301 (-3.7A)	0.62A	4krhB-4htfB: 12.5	4krhB-4htfB: 21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OKX_A_198A1002_2 (ANDROGEN RECEPTOR)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 6	LEU B 139 MET B 41 LEU B 46 ILE B 70	None	1.05A	4okxA-4htfB: undetectable	4okxA-4htfB: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGH_A_SAMA401_0 (CAFFEIC ACID O-METHYLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 11	GLY B 52 GLY B 53 THR B 58 ASP B 73 LEU B 74	SAM B 301 (-3.5A) SAM B 301 (-3.8A) None SAM B 301 (-3.1A) SAM B 301 (-4.2A)	0.84A	4pghA-4htfB: 14.9	4pghA-4htfB: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGH_B_SAMB401_0 (CAFFEIC ACID O-METHYLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	ASP B 50 GLY B 52 THR B 58 ASP B 73 LEU B 74	SAM B 301 ( 4.7A) SAM B 301 (-3.5A) None SAM B 301 (-3.1A) SAM B 301 (-4.2A)	0.95A	4pghB-4htfB: 14.8	4pghB-4htfB: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGH_D_SAMD401_0 (CAFFEIC ACID O-METHYLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 53 THR B 58 ASP B 73 LEU B 74	SAM B 301 (-3.5A) SAM B 301 (-3.8A) None SAM B 301 (-3.1A) SAM B 301 (-4.2A)	1.01A	4pghD-4htfB: 4.4	4pghD-4htfB: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QDJ_A_SAMA301_0 (MAGNESIUM-PROTOPORPH YRIN O-METHYLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 SER B 75 MET B 78 VAL B 121	SAM B 301 (-3.5A) SAM B 301 (-3.4A) SAM B 301 (-4.7A) SAM B 301 (-4.0A) SAM B 301 ( 4.3A)	0.34A	4qdjA-4htfB: 18.8	4qdjA-4htfB: 26.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCI_A_SAMA2409_0 (RNA-DIRECTED RNA POLYMERASE L)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 GLY B 56 LEU B 74 ALA B 102	SAM B 301 (-3.5A) SAM B 301 (-3.4A) None SAM B 301 (-4.2A) SAM B 301 (-3.7A)	0.57A	4uciA-4htfB: 8.6	4uciA-4htfB: 25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCI_B_SAMB2409_0 (RNA-DIRECTED RNA POLYMERASE L)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 GLY B 56 LEU B 74 ALA B 102	SAM B 301 (-3.5A) SAM B 301 (-3.4A) None SAM B 301 (-4.2A) SAM B 301 (-3.7A)	0.56A	4uciB-4htfB: 8.6	4uciB-4htfB: 25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCK_A_SAMA2409_0 (RNA-DIRECTED RNA POLYMERASE L)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 GLY B 56 LEU B 74 ALA B 102	SAM B 301 (-3.5A) SAM B 301 (-3.4A) None SAM B 301 (-4.2A) SAM B 301 (-3.7A)	0.58A	4uckA-4htfB: 8.5	4uckA-4htfB: 25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1B_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 7	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.92A	5b1bA-4htfB: undetectable 5b1bJ-4htfB: undetectable	5b1bA-4htfB: 18.97 5b1bJ-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BW4_A_SAMA301_0 (16S RRNA (ADENINE(1408)-N(1)) -METHYLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 GLY B 54 THR B 58 ASP B 73 LEU B 117	SAM B 301 (-3.5A) SAM B 301 (-3.4A) None SAM B 301 (-3.1A) None	1.07A	5bw4A-4htfB: 12.0	5bw4A-4htfB: 27.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DPD_A_SAMA601_0 (PROTEIN LYSINE METHYLTRANSFERASE 1)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	6 / 12	GLY B 52 LEU B 74 SER B 75 HIS B 119 VAL B 121 VAL B 125	SAM B 301 (-3.5A) SAM B 301 (-4.2A) SAM B 301 (-4.7A) None SAM B 301 ( 4.3A) None	1.18A	5dpdA-4htfB: 15.8	5dpdA-4htfB: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DPD_B_SAMB601_0 (PROTEIN LYSINE METHYLTRANSFERASE 1)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	6 / 12	GLY B 52 ASP B 73 LEU B 74 SER B 75 VAL B 121 VAL B 125	SAM B 301 (-3.5A) SAM B 301 (-3.1A) SAM B 301 (-4.2A) SAM B 301 (-4.7A) SAM B 301 ( 4.3A) None	0.68A	5dpdB-4htfB: 4.9	5dpdB-4htfB: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DPD_B_SAMB601_0 (PROTEIN LYSINE METHYLTRANSFERASE 1)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLY B 52 ASP B 73 LEU B 74 SER B 75 VAL B 125	SAM B 301 (-3.5A) SAM B 301 (-3.1A) SAM B 301 (-4.2A) SAM B 301 (-4.7A) None	1.01A	5dpdB-4htfB: 4.9	5dpdB-4htfB: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I6X_A_8PRA705_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 10	ALA B 86 ILE B 60 GLY B 66 GLY B 90 VAL B 69	None	1.12A	5i6xA-4htfB: undetectable	5i6xA-4htfB: 18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IY5_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 7	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.93A	5iy5A-4htfB: undetectable 5iy5J-4htfB: undetectable	5iy5A-4htfB: 18.97 5iy5J-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0W_B_SAMB501_1 (PEPTIDE N-METHYLTRANSFERASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 5	SER B 107 ALA B 106 GLN B 103 THR B 134	None None SAM B 301 (-3.3A) None	1.04A	5n0wB-4htfB: 2.6	5n0wB-4htfB: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X5Q_B_D16B402_1 (THYMIDYLATE SYNTHASE)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	5 / 12	GLU B 232 ILE B 29 GLY B 245 MET B 148 ALA B 120	None None None None SAM B 301 (-4.0A)	1.12A	5x5qB-4htfB: undetectable	5x5qB-4htfB: 22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDQ_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 7	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.88A	5xdqN-4htfB: undetectable 5xdqW-4htfB: undetectable	5xdqN-4htfB: 18.97 5xdqW-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDX_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 8	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.87A	5xdxN-4htfB: undetectable 5xdxW-4htfB: undetectable	5xdxN-4htfB: 18.97 5xdxW-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCP_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 7	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.91A	5zcpA-4htfB: undetectable 5zcpJ-4htfB: undetectable	5zcpA-4htfB: 18.97 5zcpJ-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCQ_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 7	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.94A	5zcqA-4htfB: undetectable 5zcqJ-4htfB: undetectable	5zcqA-4htfB: 18.97 5zcqJ-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCQ_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 8	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.93A	5zcqN-4htfB: undetectable 5zcqW-4htfB: undetectable	5zcqN-4htfB: 18.97 5zcqW-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BQG_A_ERMA1201_2 (5-HYDROXYTRYPTAMINE RECEPTOR 2C,SOLUBLE CYTOCHROME B562)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 5	VAL B 69 LEU B 117 VAL B 121 LEU B 135	None None SAM B 301 ( 4.3A) None	0.89A	6bqgA-4htfB: undetectable	6bqgA-4htfB: 12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMF_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 7	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.91A	6nmfA-4htfB: undetectable 6nmfJ-4htfB: undetectable	6nmfA-4htfB: 18.97 6nmfJ-4htfB: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMP_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4htf	S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE (Escherichia coli)	4 / 5	ILE B 116 LEU B 135 THR B 111 LEU B 109	None	0.89A	6nmpN-4htfB: undetectable 6nmpW-4htfB: undetectable	6nmpN-4htfB: 18.97 6nmpW-4htfB: 13.07

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1V54_W_CHDW4060_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.89A","1v54N-4htfB:undetectable;1v54W-4htfB:undetectable","1v54N-4htfB:18.97;1v54W-4htfB:13.07"],["1V55_J_CHDJ3060_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.87A","1v55A-4htfB:undetectable;1v55J-4htfB:undetectable","1v55A-4htfB:18.97;1v55J-4htfB:13.07"],["1YA3_A_STRA1001_2","MINERALOCORTICOID RECEPTOR","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"LEU B 139;LEU B 147;SER B 146;LEU B 117","None","1.06A","1ya3A-4htfB:undetectable","1ya3A-4htfB:21.45"],["1YAJ_G_BEZG3385_0","CES1 PROTEIN","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",3,"SER B 146;VAL B  48;LEU B 115","None","0.72A","1yajG-4htfB:undetectable","1yajG-4htfB:19.77"],["2C12_C_SPMC1434_1","NITROALKANE OXIDASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"LEU B 132;LEU B 117;SER B 146;LEU B 145;VAL B 144","None","1.10A","2c12C-4htfB:undetectable","2c12C-4htfB:20.27"],["2C12_F_SPMF1433_1","NITROALKANE OXIDASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"LEU B 132;ALA B  51;LEU B 117;SER B 146;LEU B 145","None","1.33A","2c12F-4htfB:undetectable","2c12F-4htfB:20.27"],["2EIJ_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.89A","2eijN-4htfB:undetectable;2eijW-4htfB:undetectable","2eijN-4htfB:18.97;2eijW-4htfB:13.07"],["2EIK_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.90A","2eikN-4htfB:undetectable;2eikW-4htfB:undetectable","2eikN-4htfB:18.97;2eikW-4htfB:13.07"],["2EIL_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.91A","2eilN-4htfB:undetectable;2eilW-4htfB:undetectable","2eilN-4htfB:18.97;2eilW-4htfB:13.07"],["2GLU_A_SAMA301_0","YCGJ","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;THR B  58;ASP B  73;ALA B 102","SAM B 301 (-3.5A);SAM B 301 (-3.4A);None;SAM B 301 (-3.1A);SAM B 301 (-3.7A)","0.75A","2gluA-4htfB:18.5","2gluA-4htfB:24.05"],["2OXT_B_SAMB300_0","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;GLY B  56;LEU B  74;VAL B 121","SAM B 301 (-3.5A);SAM B 301 (-3.4A);None;SAM B 301 (-4.2A);SAM B 301 ( 4.3A)","0.76A","2oxtB-4htfB:8.5","2oxtB-4htfB:21.52"],["2OXT_D_SAMD300_0","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"ASP B  50;GLY B  52;GLY B  54;LEU B  74;VAL B 121","SAM B 301 ( 4.7A);SAM B 301 (-3.5A);SAM B 301 (-3.4A);SAM B 301 (-4.2A);SAM B 301 ( 4.3A)","0.65A","2oxtD-4htfB:8.5","2oxtD-4htfB:21.52"],["3ABL_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.91A","3ablN-4htfB:undetectable;3ablW-4htfB:undetectable","3ablN-4htfB:18.97;3ablW-4htfB:13.07"],["3AG3_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.91A","3ag3A-4htfB:undetectable;3ag3J-4htfB:undetectable","3ag3A-4htfB:18.97;3ag3J-4htfB:13.07"],["3ASN_W_CHDW1059_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.90A","3asnN-4htfB:undetectable;3asnW-4htfB:undetectable","3asnN-4htfB:18.97;3asnW-4htfB:13.07"],["3G88_A_SAMA303_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;ASP B  73;ALA B 102;ALA B 120","SAM B 301 (-3.5A);SAM B 301 (-3.4A);SAM B 301 (-3.1A);SAM B 301 (-3.7A);SAM B 301 (-4.0A)","0.75A","3g88A-4htfB:13.4","3g88A-4htfB:23.15"],["3G88_B_SAMB303_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;ASP B  73;ALA B 102;ALA B 120","SAM B 301 (-3.5A);SAM B 301 (-3.4A);SAM B 301 (-3.1A);SAM B 301 (-3.7A);SAM B 301 (-4.0A)","0.74A","3g88B-4htfB:13.5","3g88B-4htfB:23.15"],["3G89_A_SAMA303_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;ASP B  73;ALA B 102;ALA B 120","SAM B 301 (-3.5A);SAM B 301 (-3.4A);SAM B 301 (-3.1A);SAM B 301 (-3.7A);SAM B 301 (-4.0A)","0.68A","3g89A-4htfB:13.5","3g89A-4htfB:23.15"],["3G89_B_SAMB303_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;ASP B  73;ALA B 101;ALA B 120","SAM B 301 (-3.5A);SAM B 301 (-3.4A);SAM B 301 (-3.1A);SAM B 301 (-4.2A);SAM B 301 (-4.0A)","0.96A","3g89B-4htfB:13.4","3g89B-4htfB:23.15"],["3G89_B_SAMB303_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;ASP B  73;ALA B 102;ALA B 120","SAM B 301 (-3.5A);SAM B 301 (-3.4A);SAM B 301 (-3.1A);SAM B 301 (-3.7A);SAM B 301 (-4.0A)","0.66A","3g89B-4htfB:13.4","3g89B-4htfB:23.15"],["3G8B_A_SAMA303_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;ASP B  73;ALA B 101;ALA B 120","SAM B 301 (-3.5A);SAM B 301 (-3.4A);SAM B 301 (-3.1A);SAM B 301 (-4.2A);SAM B 301 (-4.0A)","0.92A","3g8bA-4htfB:13.5","3g8bA-4htfB:23.15"],["3G8B_A_SAMA303_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;ASP B  73;ALA B 102;ALA B 120","SAM B 301 (-3.5A);SAM B 301 (-3.4A);SAM B 301 (-3.1A);SAM B 301 (-3.7A);SAM B 301 (-4.0A)","0.68A","3g8bA-4htfB:13.5","3g8bA-4htfB:23.15"],["3G8B_B_SAMB303_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;ASP B  73;ALA B 101;ALA B 120","SAM B 301 (-3.5A);SAM B 301 (-3.4A);SAM B 301 (-3.1A);SAM B 301 (-4.2A);SAM B 301 (-4.0A)","0.93A","3g8bB-4htfB:12.3","3g8bB-4htfB:23.15"],["3G8B_B_SAMB303_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;ASP B  73;ALA B 102;ALA B 120","SAM B 301 (-3.5A);SAM B 301 (-3.4A);SAM B 301 (-3.1A);SAM B 301 (-3.7A);SAM B 301 (-4.0A)","0.69A","3g8bB-4htfB:12.3","3g8bB-4htfB:23.15"],["3LCV_B_SAMB301_1","SISOMICIN-GENTAMICIN RESISTANCE METHYLASE SGM","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",3,"ARG B  26;ASP B  73;GLN B 103","SO4 B 302 ( 4.1A);SAM B 301 (-3.1A);SAM B 301 (-3.3A)","0.86A","3lcvB-4htfB:10.0","3lcvB-4htfB:24.29"],["4FR0_A_SAMA401_0","ARSENIC METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  56;GLY B  53;LEU B 117;ILE B  60;GLU B  64","None;SAM B 301 (-3.8A);None;None;None","1.12A","4fr0A-4htfB:14.9","4fr0A-4htfB:22.73"],["4HTF_A_ACTA303_0","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",3,"TYR B 150;HIS B 158;ARG B 246","None","0.14A","4htfA-4htfB:37.9","4htfA-4htfB:100.00"],["4HTF_A_SAMA301_0","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",12,"ARG B  26;GLY B  52;GLY B  53;GLY B  54;LEU B  74;SER B  75;ALA B 102;GLN B 103;HIS B 119;VAL B 121;TRP B 124;VAL B 125","SO4 B 302 ( 4.1A);SAM B 301 (-3.5A);SAM B 301 (-3.8A);SAM B 301 (-3.4A);SAM B 301 (-4.2A);SAM B 301 (-4.7A);SAM B 301 (-3.7A);SAM B 301 (-3.3A);None;SAM B 301 ( 4.3A);None;None","0.27A","4htfA-4htfB:37.9","4htfA-4htfB:100.00"],["4HTF_A_SAMA301_0","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",8,"ARG B  26;GLY B  53;LEU B  74;SER B  75;GLN B 103;VAL B 121;TRP B 124;VAL B 125","SO4 B 302 ( 4.1A);SAM B 301 (-3.8A);SAM B 301 (-4.2A);SAM B 301 (-4.7A);SAM B 301 (-3.3A);SAM B 301 ( 4.3A);None;None","1.08A","4htfA-4htfB:37.9","4htfA-4htfB:100.00"],["4HTF_A_SAMA301_0","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",8,"ARG B  26;GLY B  54;LEU B  74;ALA B 102;GLN B 103;VAL B 121;TRP B 124;VAL B 125","SO4 B 302 ( 4.1A);SAM B 301 (-3.4A);SAM B 301 (-4.2A);SAM B 301 (-3.7A);SAM B 301 (-3.3A);SAM B 301 ( 4.3A);None;None","0.94A","4htfA-4htfB:37.9","4htfA-4htfB:100.00"],["4HTF_B_SAMB301_0","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",12,"ARG B  26;GLY B  52;GLY B  53;GLY B  54;LEU B  74;SER B  75;ALA B 102;GLN B 103;HIS B 119;VAL B 121;TRP B 124;VAL B 125","SO4 B 302 ( 4.1A);SAM B 301 (-3.5A);SAM B 301 (-3.8A);SAM B 301 (-3.4A);SAM B 301 (-4.2A);SAM B 301 (-4.7A);SAM B 301 (-3.7A);SAM B 301 (-3.3A);None;SAM B 301 ( 4.3A);None;None","0.00A","4htfB-4htfB:43.2","4htfB-4htfB:100.00"],["4KRH_A_SAMA900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;LEU B  74;SER B  75;ALA B 102","SAM B 301 (-3.5A);SAM B 301 (-3.4A);SAM B 301 (-4.2A);SAM B 301 (-4.7A);SAM B 301 (-3.7A)","0.69A","4krhA-4htfB:12.3","4krhA-4htfB:21.87"],["4KRH_B_SAMB900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;LEU B  74;SER B  75;ALA B 102","SAM B 301 (-3.5A);SAM B 301 (-3.4A);SAM B 301 (-4.2A);SAM B 301 (-4.7A);SAM B 301 (-3.7A)","0.62A","4krhB-4htfB:12.5","4krhB-4htfB:21.87"],["4OKX_A_198A1002_2","ANDROGEN RECEPTOR","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"LEU B 139;MET B  41;LEU B  46;ILE B  70","None","1.05A","4okxA-4htfB:undetectable","4okxA-4htfB:22.71"],["4PGH_A_SAMA401_0","CAFFEIC ACID O-METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  53;THR B  58;ASP B  73;LEU B  74","SAM B 301 (-3.5A);SAM B 301 (-3.8A);None;SAM B 301 (-3.1A);SAM B 301 (-4.2A)","0.84A","4pghA-4htfB:14.9","4pghA-4htfB:20.85"],["4PGH_B_SAMB401_0","CAFFEIC ACID O-METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"ASP B  50;GLY B  52;THR B  58;ASP B  73;LEU B  74","SAM B 301 ( 4.7A);SAM B 301 (-3.5A);None;SAM B 301 (-3.1A);SAM B 301 (-4.2A)","0.95A","4pghB-4htfB:14.8","4pghB-4htfB:20.85"],["4PGH_D_SAMD401_0","CAFFEIC ACID O-METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  53;THR B  58;ASP B  73;LEU B  74","SAM B 301 (-3.5A);SAM B 301 (-3.8A);None;SAM B 301 (-3.1A);SAM B 301 (-4.2A)","1.01A","4pghD-4htfB:4.4","4pghD-4htfB:20.85"],["4QDJ_A_SAMA301_0","MAGNESIUM-PROTOPORPHYRIN O-METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;SER B  75;MET B  78;VAL B 121","SAM B 301 (-3.5A);SAM B 301 (-3.4A);SAM B 301 (-4.7A);SAM B 301 (-4.0A);SAM B 301 ( 4.3A)","0.34A","4qdjA-4htfB:18.8","4qdjA-4htfB:26.13"],["4UCI_A_SAMA2409_0","RNA-DIRECTED RNA POLYMERASE L","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;GLY B  56;LEU B  74;ALA B 102","SAM B 301 (-3.5A);SAM B 301 (-3.4A);None;SAM B 301 (-4.2A);SAM B 301 (-3.7A)","0.57A","4uciA-4htfB:8.6","4uciA-4htfB:25.12"],["4UCI_B_SAMB2409_0","RNA-DIRECTED RNA POLYMERASE L","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;GLY B  56;LEU B  74;ALA B 102","SAM B 301 (-3.5A);SAM B 301 (-3.4A);None;SAM B 301 (-4.2A);SAM B 301 (-3.7A)","0.56A","4uciB-4htfB:8.6","4uciB-4htfB:25.12"],["4UCK_A_SAMA2409_0","RNA-DIRECTED RNA POLYMERASE L","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;GLY B  56;LEU B  74;ALA B 102","SAM B 301 (-3.5A);SAM B 301 (-3.4A);None;SAM B 301 (-4.2A);SAM B 301 (-3.7A)","0.58A","4uckA-4htfB:8.5","4uckA-4htfB:25.12"],["5B1B_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.92A","5b1bA-4htfB:undetectable;5b1bJ-4htfB:undetectable","5b1bA-4htfB:18.97;5b1bJ-4htfB:13.07"],["5BW4_A_SAMA301_0","16S RRNA (ADENINE(1408)-N(1))-METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;GLY B  54;THR B  58;ASP B  73;LEU B 117","SAM B 301 (-3.5A);SAM B 301 (-3.4A);None;SAM B 301 (-3.1A);None","1.07A","5bw4A-4htfB:12.0","5bw4A-4htfB:27.48"],["5DPD_A_SAMA601_0","PROTEIN LYSINE METHYLTRANSFERASE 1","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",6,"GLY B  52;LEU B  74;SER B  75;HIS B 119;VAL B 121;VAL B 125","SAM B 301 (-3.5A);SAM B 301 (-4.2A);SAM B 301 (-4.7A);None;SAM B 301 ( 4.3A);None","1.18A","5dpdA-4htfB:15.8","5dpdA-4htfB:17.86"],["5DPD_B_SAMB601_0","PROTEIN LYSINE METHYLTRANSFERASE 1","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",6,"GLY B  52;ASP B  73;LEU B  74;SER B  75;VAL B 121;VAL B 125","SAM B 301 (-3.5A);SAM B 301 (-3.1A);SAM B 301 (-4.2A);SAM B 301 (-4.7A);SAM B 301 ( 4.3A);None","0.68A","5dpdB-4htfB:4.9","5dpdB-4htfB:17.86"],["5DPD_B_SAMB601_0","PROTEIN LYSINE METHYLTRANSFERASE 1","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLY B  52;ASP B  73;LEU B  74;SER B  75;VAL B 125","SAM B 301 (-3.5A);SAM B 301 (-3.1A);SAM B 301 (-4.2A);SAM B 301 (-4.7A);None","1.01A","5dpdB-4htfB:4.9","5dpdB-4htfB:17.86"],["5I6X_A_8PRA705_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"ALA B  86;ILE B  60;GLY B  66;GLY B  90;VAL B  69","None","1.12A","5i6xA-4htfB:undetectable","5i6xA-4htfB:18.44"],["5IY5_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.93A","5iy5A-4htfB:undetectable;5iy5J-4htfB:undetectable","5iy5A-4htfB:18.97;5iy5J-4htfB:13.07"],["5N0W_B_SAMB501_1","PEPTIDE N-METHYLTRANSFERASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"SER B 107;ALA B 106;GLN B 103;THR B 134","None;None;SAM B 301 (-3.3A);None","1.04A","5n0wB-4htfB:2.6","5n0wB-4htfB:22.03"],["5X5Q_B_D16B402_1","THYMIDYLATE SYNTHASE","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",5,"GLU B 232;ILE B  29;GLY B 245;MET B 148;ALA B 120","None;None;None;None;SAM B 301 (-4.0A)","1.12A","5x5qB-4htfB:undetectable","5x5qB-4htfB:22.32"],["5XDQ_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.88A","5xdqN-4htfB:undetectable;5xdqW-4htfB:undetectable","5xdqN-4htfB:18.97;5xdqW-4htfB:13.07"],["5XDX_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.87A","5xdxN-4htfB:undetectable;5xdxW-4htfB:undetectable","5xdxN-4htfB:18.97;5xdxW-4htfB:13.07"],["5ZCP_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.91A","5zcpA-4htfB:undetectable;5zcpJ-4htfB:undetectable","5zcpA-4htfB:18.97;5zcpJ-4htfB:13.07"],["5ZCQ_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.94A","5zcqA-4htfB:undetectable;5zcqJ-4htfB:undetectable","5zcqA-4htfB:18.97;5zcqJ-4htfB:13.07"],["5ZCQ_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.93A","5zcqN-4htfB:undetectable;5zcqW-4htfB:undetectable","5zcqN-4htfB:18.97;5zcqW-4htfB:13.07"],["6BQG_A_ERMA1201_2","5-HYDROXYTRYPTAMINE RECEPTOR 2C,SOLUBLE CYTOCHROME B562","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"VAL B  69;LEU B 117;VAL B 121;LEU B 135","None;None;SAM B 301 ( 4.3A);None","0.89A","6bqgA-4htfB:undetectable","6bqgA-4htfB:12.27"],["6NMF_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.91A","6nmfA-4htfB:undetectable;6nmfJ-4htfB:undetectable","6nmfA-4htfB:18.97;6nmfJ-4htfB:13.07"],["6NMP_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4htf","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","Escherichia coli",4,"ILE B 116;LEU B 135;THR B 111;LEU B 109","None","0.89A","6nmpN-4htfB:undetectable;6nmpW-4htfB:undetectable","6nmpN-4htfB:18.97;6nmpW-4htfB:13.07"]]