SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4htw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 4htw GAG PROTEIN
(Simian
immunodeficiency
virus) 		4 / 8 PHE A  39
ILE A  51
LEU A  55
LEU A  14
 None
 0.90A 1eupA-4htwA:
undetectable		 1eupA-4htwA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 4htw GAG PROTEIN
(Simian
immunodeficiency
virus) 		5 / 12 ILE A  51
ILE A 132
PHE A  39
ILE A  68
VAL A  58
 None
 1.03A 1qhyA-4htwA:
undetectable		 1qhyA-4htwA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4htw GAG PROTEIN
(Simian
immunodeficiency
virus) 		4 / 5 LEU A  14
THR A  18
THR A  47
HIS A  11
 None
 1.20A 2zj0B-4htwA:
undetectable		 2zj0B-4htwA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4htw GAG PROTEIN
(Simian
immunodeficiency
virus) 		4 / 5 LEU A  14
THR A  18
THR A  47
HIS A  11
 None
 1.19A 2zj0C-4htwA:
undetectable		 2zj0C-4htwA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 4htw GAG PROTEIN
(Simian
immunodeficiency
virus) 		4 / 6 THR A  47
GLY A 125
ARG A  94
ILE A 101
 None
 1.08A 4ac9C-4htwA:
undetectable		 4ac9C-4htwA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4htw GAG PROTEIN
(Simian
immunodeficiency
virus) 		4 / 6 THR A  47
GLY A 125
ARG A  94
ILE A 101
 None
 1.08A 4acaC-4htwA:
undetectable		 4acaC-4htwA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4htw GAG PROTEIN
(Simian
immunodeficiency
virus) 		4 / 6 ASN A 120
PRO A 121
ILE A 122
GLU A  95
 None
 1.22A 6h7uA-4htwA:
undetectable		 6h7uA-4htwA:
13.46