SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4huh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_A_FFOA1293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	4huh	TAIL CONNECTOR PROTEIN GP15 (Escherichia virus T4)	3 / 3	GLU A 151 TYR A 109 PHE A 153	None	0.95A	1eqbB-4huhA: undetectable	1eqbB-4huhA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_B_FFOB2293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4huh	TAIL CONNECTOR PROTEIN GP15 (Escherichia virus T4)	3 / 3	GLU A 151 TYR A 109 PHE A 153	None	0.93A	1eqbA-4huhA: undetectable	1eqbA-4huhA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_C_FFOC3293_2 (SERINE HYDROXYMETHYLTRANSFE RASE)	4huh	TAIL CONNECTOR PROTEIN GP15 (Escherichia virus T4)	3 / 3	GLU A 151 TYR A 109 PHE A 153	None	0.94A	1eqbD-4huhA: undetectable	1eqbD-4huhA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_D_FFOD4293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4huh	TAIL CONNECTOR PROTEIN GP15 (Escherichia virus T4)	3 / 3	GLU A 151 TYR A 109 PHE A 153	None	0.94A	1eqbC-4huhA: undetectable	1eqbC-4huhA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S8P_A_SAMA500_1 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	4huh	TAIL CONNECTOR PROTEIN GP15 (Escherichia virus T4)	3 / 3	HIS A 78 SER A 189 GLU A 119	None	0.87A	3s8pA-4huhA: undetectable	3s8pA-4huhA: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CDP_H_EVPH2101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B)	4huh	TAIL CONNECTOR PROTEIN GP15 (Escherichia virus T4)	4 / 6	SER A 9 GLY A 154 ASP A 156 GLY A 207	None	0.74A	5cdpA-4huhA: 2.3 5cdpB-4huhA: undetectable	5cdpA-4huhA: 20.45 5cdpB-4huhA: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TDZ_A_ADNA905_1 (ATP-CITRATE SYNTHASE)	4huh	TAIL CONNECTOR PROTEIN GP15 (Escherichia virus T4)	4 / 6	THR A 211 ASP A 222 LEU A 223 ASP A 19	None	1.17A	5tdzA-4huhA: undetectable	5tdzA-4huhA: 18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GSD_A_STRA401_0 (PROGESTERONE 5-BETA-REDUCTASE)	4huh	TAIL CONNECTOR PROTEIN GP15 (Escherichia virus T4)	5 / 12	VAL A 39 PHE A 21 ILE A 75 VAL A 134 ILE A 122	None	1.32A	6gsdA-4huhA: undetectable	6gsdA-4huhA: 14.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQB_A_FFOA1293_1","SERINE HYDROXYMETHYLTRANSFERASE","4huh","TAIL CONNECTOR PROTEIN GP15","Escherichia virus T4",3,"GLU A 151;TYR A 109;PHE A 153","None","0.95A","1eqbB-4huhA:undetectable","1eqbB-4huhA:20.85"],["1EQB_B_FFOB2293_0","SERINE HYDROXYMETHYLTRANSFERASE","4huh","TAIL CONNECTOR PROTEIN GP15","Escherichia virus T4",3,"GLU A 151;TYR A 109;PHE A 153","None","0.93A","1eqbA-4huhA:undetectable","1eqbA-4huhA:20.85"],["1EQB_C_FFOC3293_2","SERINE HYDROXYMETHYLTRANSFERASE","4huh","TAIL CONNECTOR PROTEIN GP15","Escherichia virus T4",3,"GLU A 151;TYR A 109;PHE A 153","None","0.94A","1eqbD-4huhA:undetectable","1eqbD-4huhA:20.85"],["1EQB_D_FFOD4293_0","SERINE HYDROXYMETHYLTRANSFERASE","4huh","TAIL CONNECTOR PROTEIN GP15","Escherichia virus T4",3,"GLU A 151;TYR A 109;PHE A 153","None","0.94A","1eqbC-4huhA:undetectable","1eqbC-4huhA:20.85"],["3S8P_A_SAMA500_1","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","4huh","TAIL CONNECTOR PROTEIN GP15","Escherichia virus T4",3,"HIS A  78;SER A 189;GLU A 119","None","0.87A","3s8pA-4huhA:undetectable","3s8pA-4huhA:23.08"],["5CDP_H_EVPH2101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B","4huh","TAIL CONNECTOR PROTEIN GP15","Escherichia virus T4",4,"SER A   9;GLY A 154;ASP A 156;GLY A 207","None","0.74A","5cdpA-4huhA:2.3;5cdpB-4huhA:undetectable","5cdpA-4huhA:20.45;5cdpB-4huhA:21.11"],["5TDZ_A_ADNA905_1","ATP-CITRATE SYNTHASE","4huh","TAIL CONNECTOR PROTEIN GP15","Escherichia virus T4",4,"THR A 211;ASP A 222;LEU A 223;ASP A  19","None","1.17A","5tdzA-4huhA:undetectable","5tdzA-4huhA:18.27"],["6GSD_A_STRA401_0","PROGESTERONE 5-BETA-REDUCTASE","4huh","TAIL CONNECTOR PROTEIN GP15","Escherichia virus T4",5,"VAL A  39;PHE A  21;ILE A  75;VAL A 134;ILE A 122","None","1.32A","6gsdA-4huhA:undetectable","6gsdA-4huhA:14.56"]]