SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4huj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		3 / 3 SER A 114
GLU A 115
GLU A 111
 None
 0.68A 1eqbD-4hujA:
undetectable		 1eqbD-4hujA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		3 / 3 SER A 114
GLU A 115
GLU A 111
 None
 0.69A 1eqbB-4hujA:
undetectable		 1eqbB-4hujA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 GLY A 151
ASP A 173
ILE A 164
ILE A  86
ALA A  90
 None
 1.03A 1sguB-4hujA:
undetectable		 1sguB-4hujA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 8 SER A  48
PHE A  20
LEU A 163
LEU A 134
 None
 0.95A 2bfpA-4hujA:
undetectable		 2bfpA-4hujA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 8 SER A  48
PHE A  20
LEU A 163
LEU A 134
 None
 1.04A 2bfpD-4hujA:
undetectable		 2bfpD-4hujA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 10 ALA A 131
ALA A 135
GLU A  18
ALA A  15
SER A  14
 None
 1.01A 2r2vC-4hujA:
undetectable
2r2vF-4hujA:
undetectable
2r2vG-4hujA:
undetectable		 2r2vC-4hujA:
10.91
2r2vF-4hujA:
10.91
2r2vG-4hujA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 11 ALA A  90
VAL A 113
GLY A   8
ILE A   7
VAL A  76
 None
 1.11A 2uxpB-4hujA:
undetectable		 2uxpB-4hujA:
25.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 VAL A  62
ALA A   5
ALA A  90
ILE A  25
THR A   2
 None
 1.29A 3dl9B-4hujA:
undetectable		 3dl9B-4hujA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		6 / 12 GLY A  13
SER A  14
ALA A 135
LEU A 134
ILE A   7
PRO A  68
 None
 1.47A 3mb5A-4hujA:
4.2		 3mb5A-4hujA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 7 TYR A  69
VAL A  62
VAL A 117
ILE A   7
 None
 1.00A 3mssB-4hujA:
undetectable		 3mssB-4hujA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 VAL A  63
VAL A  79
LEU A  58
GLY A 119
ALA A 120
 None
 1.02A 3n8wA-4hujA:
undetectable		 3n8wA-4hujA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 VAL A  63
VAL A  79
LEU A  58
GLY A 119
ALA A 120
 None
 0.95A 3pghC-4hujA:
undetectable		 3pghC-4hujA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 6 TYR A  69
VAL A  62
VAL A 117
ILE A   7
 None
 0.98A 3pyyA-4hujA:
undetectable		 3pyyA-4hujA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 VAL A  63
VAL A  79
LEU A  58
GLY A 119
ALA A 120
 None
 1.02A 3rr3A-4hujA:
undetectable		 3rr3A-4hujA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 VAL A  63
VAL A  79
LEU A  58
GLY A 119
ALA A 120
 None
 1.03A 3rr3B-4hujA:
undetectable		 3rr3B-4hujA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 VAL A  63
VAL A  79
LEU A  58
GLY A 119
ALA A 120
 None
 1.03A 3rr3C-4hujA:
undetectable		 3rr3C-4hujA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 VAL A  63
VAL A  79
LEU A  58
GLY A 119
ALA A 120
 None
 1.03A 3rr3D-4hujA:
undetectable		 3rr3D-4hujA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 6 VAL A  88
VAL A 160
ILE A 164
LEU A 134
 None
 0.98A 4l1wB-4hujA:
undetectable		 4l1wB-4hujA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 10 VAL A  63
VAL A  79
LEU A  58
GLY A 119
ALA A 120
 None
 1.00A 4ph9A-4hujA:
undetectable		 4ph9A-4hujA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 10 VAL A  63
VAL A  79
LEU A  58
GLY A 119
ALA A 120
 None
 0.99A 4ph9B-4hujA:
undetectable		 4ph9B-4hujA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 VAL A 113
LEU A 177
SER A 180
LEU A  16
ILE A 164
 None
 1.11A 5hv1A-4hujA:
undetectable		 5hv1A-4hujA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 4huj UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		3 / 3 HIS A 153
ASN A 152
LEU A 177
 None
 0.81A 6f7lB-4hujA:
3.5		 6f7lB-4hujA:
19.16