SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hut'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4P_A_TPVA300_2 (PROTEASE)	4hut	COB(I)YRINIC ACID A,C-DIAMIDE ADENOSYLTRANSFERASE (Salmonella enterica)	5 / 9	LEU A 126 VAL A 33 ILE A 144 VAL A 156 ILE A 158	None	0.94A	2o4pB-4hutA: undetectable	2o4pB-4hutA: 20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YLO_A_TESA1920_1 (ANDROGEN RECEPTOR)	4hut	COB(I)YRINIC ACID A,C-DIAMIDE ADENOSYLTRANSFERASE (Salmonella enterica)	5 / 12	LEU A 126 MET A 123 MET A 115 THR A 48 PHE A 34	None	1.45A	2yloA-4hutA: undetectable	2yloA-4hutA: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OAD_A_CLMA206_0 (GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794)	4hut	COB(I)YRINIC ACID A,C-DIAMIDE ADENOSYLTRANSFERASE (Salmonella enterica)	4 / 4	ALA A 100 ALA A 103 ALA A 104 ALA A 107	None	0.11A	4oadA-4hutA: undetectable	4oadA-4hutA: 19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OAE_A_CLMA208_0 (GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794)	4hut	COB(I)YRINIC ACID A,C-DIAMIDE ADENOSYLTRANSFERASE (Salmonella enterica)	4 / 4	ALA A 100 ALA A 103 ALA A 104 ALA A 107	None	0.09A	4oaeA-4hutA: undetectable	4oaeA-4hutA: 20.31

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2O4P_A_TPVA300_2","PROTEASE;PROTEASE","4hut","COB(I)YRINIC ACID A,C-DIAMIDE ADENOSYLTRANSFERASE","Salmonella enterica",5,"LEU A 126;VAL A  33;ILE A 144;VAL A 156;ILE A 158","None","0.94A","2o4pB-4hutA:undetectable","2o4pB-4hutA:20.11"],["2YLO_A_TESA1920_1","ANDROGEN RECEPTOR","4hut","COB(I)YRINIC ACID A,C-DIAMIDE ADENOSYLTRANSFERASE","Salmonella enterica",5,"LEU A 126;MET A 123;MET A 115;THR A  48;PHE A  34","None","1.45A","2yloA-4hutA:undetectable","2yloA-4hutA:22.52"],["4OAD_A_CLMA206_0","GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794","4hut","COB(I)YRINIC ACID A,C-DIAMIDE ADENOSYLTRANSFERASE","Salmonella enterica",4,"ALA A 100;ALA A 103;ALA A 104;ALA A 107","None","0.11A","4oadA-4hutA:undetectable","4oadA-4hutA:19.79"],["4OAE_A_CLMA208_0","GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794","4hut","COB(I)YRINIC ACID A,C-DIAMIDE ADENOSYLTRANSFERASE","Salmonella enterica",4,"ALA A 100;ALA A 103;ALA A 104;ALA A 107","None","0.09A","4oaeA-4hutA:undetectable","4oaeA-4hutA:20.31"]]