SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hv6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 4hv6 TRANSCRIPTIONAL
REGULATOR MNTR
(Bacillus
subtilis) 		4 / 4 ILE A  28
ASP A  47
LEU A  62
ARG A  24
 None
 1.47A 2a7qA-4hv6A:
undetectable		 2a7qA-4hv6A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4hv6 TRANSCRIPTIONAL
REGULATOR MNTR
(Bacillus
subtilis) 		3 / 3 TRP A 107
VAL A 117
ARG A 126
 None
 0.85A 3b0wA-4hv6A:
undetectable		 3b0wA-4hv6A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 4hv6 TRANSCRIPTIONAL
REGULATOR MNTR
(Bacillus
subtilis) 		5 / 12 GLY A  66
ILE A  28
GLN A  12
LEU A  16
ALA A  23
 None
 1.03A 5l0zA-4hv6A:
undetectable		 5l0zA-4hv6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 4hv6 TRANSCRIPTIONAL
REGULATOR MNTR
(Bacillus
subtilis) 		5 / 10 GLY A  66
ILE A  28
GLN A  12
LEU A  16
ALA A  23
 None
 1.01A 5l0zB-4hv6A:
undetectable		 5l0zB-4hv6A:
19.75