SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hvf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 4hvf GREEN FLUORESCENT
PROTEIN BLFP-Y6
(Branchiostoma
lanceolatum) 		4 / 8 LEU A  99
THR A 162
TYR A 160
ILE A  52
 None
 1.11A 1qvtA-4hvfA:
undetectable		 1qvtA-4hvfA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 4hvf GREEN FLUORESCENT
PROTEIN BLFP-Y6
(Branchiostoma
lanceolatum) 		4 / 8 PHE A 209
GLU A 211
TYR A 103
TYR A 105
 CR2  A  58 ( 4.5A)
CR2  A  58 ( 2.8A)
None
CR2  A  58 ( 4.5A)
 1.25A 2aoxA-4hvfA:
undetectable		 2aoxA-4hvfA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 4hvf GREEN FLUORESCENT
PROTEIN BLFP-Y6
(Branchiostoma
lanceolatum) 		3 / 3 ASN A 208
LEU A 200
HIS A 202
 None
 0.74A 2q6fB-4hvfA:
undetectable		 2q6fB-4hvfA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 4hvf GREEN FLUORESCENT
PROTEIN BLFP-Y6
(Branchiostoma
lanceolatum) 		4 / 8 ASN A 150
LYS A 180
PRO A  74
PHE A  67
 None
 1.45A 3bjwD-4hvfA:
undetectable		 3bjwD-4hvfA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 4hvf GREEN FLUORESCENT
PROTEIN BLFP-Y6
(Branchiostoma
lanceolatum) 		4 / 7 ILE A  57
LYS A  43
PHE A  20
GLY A  13
 CR2  A  58 ( 4.0A)
None
None
None
 1.19A 3sj0X-4hvfA:
undetectable		 3sj0X-4hvfA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 4hvf GREEN FLUORESCENT
PROTEIN BLFP-Y6
(Branchiostoma
lanceolatum) 		5 / 12 TYR A  64
TYR A 105
GLY A 114
GLU A   8
PHE A 209
 None
CR2  A  58 ( 4.5A)
None
None
CR2  A  58 ( 4.5A)
 1.24A 4wcxC-4hvfA:
undetectable		 4wcxC-4hvfA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 4hvf GREEN FLUORESCENT
PROTEIN BLFP-Y6
(Branchiostoma
lanceolatum) 		5 / 12 TYR A 105
GLY A 114
GLU A   8
PRO A  30
ALA A  78
 CR2  A  58 ( 4.5A)
None
None
None
None
 1.24A 4wcxC-4hvfA:
undetectable		 4wcxC-4hvfA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4hvf GREEN FLUORESCENT
PROTEIN BLFP-Y6
(Branchiostoma
lanceolatum) 		4 / 5 PHE A  61
LEU A  39
GLY A  24
ILE A 112
 CR2  A  58 ( 3.5A)
None
None
None
 0.94A 5ik1A-4hvfA:
undetectable		 5ik1A-4hvfA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 4hvf GREEN FLUORESCENT
PROTEIN BLFP-Y6
(Branchiostoma
lanceolatum) 		4 / 6 PHE A 116
GLY A 114
GLN A  63
TYR A 107
 CR2  A  58 ( 4.4A)
None
CR2  A  58 ( 4.9A)
None
 1.25A 6ag0A-4hvfA:
undetectable		 6ag0A-4hvfA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 4hvf GREEN FLUORESCENT
PROTEIN BLFP-Y6
(Branchiostoma
lanceolatum) 		4 / 6 PHE A 116
GLY A 114
GLN A  63
TYR A 107
 CR2  A  58 ( 4.4A)
None
CR2  A  58 ( 4.9A)
None
 1.23A 6ag0C-4hvfA:
undetectable		 6ag0C-4hvfA:
18.14