SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hvn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 4hvn HYPOTHETICAL PROTEIN
(Catenulispora
acidiphila) 		3 / 3 ARG A 103
GLY A  30
ASP A  29
 None
 0.44A 1kf6A-4hvnA:
undetectable
1kf6B-4hvnA:
undetectable		 1kf6A-4hvnA:
12.87
1kf6B-4hvnA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 4hvn HYPOTHETICAL PROTEIN
(Catenulispora
acidiphila) 		4 / 7 ALA A   9
THR A   8
ALA A  11
PRO A   4
 None
 0.96A 2ql8A-4hvnA:
undetectable
2ql8B-4hvnA:
undetectable		 2ql8A-4hvnA:
22.84
2ql8B-4hvnA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 4hvn HYPOTHETICAL PROTEIN
(Catenulispora
acidiphila) 		5 / 12 LEU A  25
LEU A  22
PHE A  26
ALA A  11
THR A  15
 None
 1.28A 2v0mC-4hvnA:
undetectable		 2v0mC-4hvnA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 4hvn HYPOTHETICAL PROTEIN
(Catenulispora
acidiphila) 		5 / 9 PRO A   4
GLY A  72
ILE A   6
LEU A 100
THR A 102
 None
 1.19A 4x3mB-4hvnA:
undetectable		 4x3mB-4hvnA:
19.85