SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hvz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NHZ_A_486A800_1 (GLUCOCORTICOID RECEPTOR)	4hvz	26 KDA PERIPLASMIC IMMUNOGENIC PROTEIN (Brucella abortus)	5 / 12	LEU A 59 ASN A 58 MET A 79 MET A 86 LEU A 96	None	1.42A	1nhzA-4hvzA: undetectable	1nhzA-4hvzA: 21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UOB_A_PNNA1311_1 (DEACETOXYCEPHALOSPOR IN C SYNTHETASE)	4hvz	26 KDA PERIPLASMIC IMMUNOGENIC PROTEIN (Brucella abortus)	3 / 3	ARG A 133 ARG A 135 ILE A 143	None	0.74A	1uobA-4hvzA: undetectable	1uobA-4hvzA: 21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_D_SAMD401_1 (METHYLTRANSFERASE NSUN4)	4hvz	26 KDA PERIPLASMIC IMMUNOGENIC PROTEIN (Brucella abortus)	3 / 3	ASP A 95 ARG A 94 ASP A 163	None	0.79A	4fp9D-4hvzA: undetectable	4fp9D-4hvzA: 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZBQ_A_DIFA602_1 (SERUM ALBUMIN)	4hvz	26 KDA PERIPLASMIC IMMUNOGENIC PROTEIN (Brucella abortus)	5 / 8	ASN A 179 ALA A 178 VAL A 177 LYS A 174 GLU A 171	None	1.47A	4zbqA-4hvzA: undetectable	4zbqA-4hvzA: 15.58

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NHZ_A_486A800_1","GLUCOCORTICOID RECEPTOR","4hvz","26 KDA PERIPLASMIC IMMUNOGENIC PROTEIN","Brucella abortus",5,"LEU A  59;ASN A  58;MET A  79;MET A  86;LEU A  96","None","1.42A","1nhzA-4hvzA:undetectable","1nhzA-4hvzA:21.33"],["1UOB_A_PNNA1311_1","DEACETOXYCEPHALOSPORIN C SYNTHETASE","4hvz","26 KDA PERIPLASMIC IMMUNOGENIC PROTEIN","Brucella abortus",3,"ARG A 133;ARG A 135;ILE A 143","None","0.74A","1uobA-4hvzA:undetectable","1uobA-4hvzA:21.54"],["4FP9_D_SAMD401_1","METHYLTRANSFERASE NSUN4","4hvz","26 KDA PERIPLASMIC IMMUNOGENIC PROTEIN","Brucella abortus",3,"ASP A  95;ARG A  94;ASP A 163","None","0.79A","4fp9D-4hvzA:undetectable","4fp9D-4hvzA:21.97"],["4ZBQ_A_DIFA602_1","SERUM ALBUMIN","4hvz","26 KDA PERIPLASMIC IMMUNOGENIC PROTEIN","Brucella abortus",5,"ASN A 179;ALA A 178;VAL A 177;LYS A 174;GLU A 171","None","1.47A","4zbqA-4hvzA:undetectable","4zbqA-4hvzA:15.58"]]