SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hwm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT6_A_DVAA8_0 (GRAMICIDIN C)	4hwm	UNCHARACTERIZED PROTEIN YEDD (Klebsiella pneumoniae)	4 / 5	GLY A 63 VAL A 59 TRP A 39 TRP A 128	None	1.48A	1nt6A-4hwmA: undetectable	1nt6A-4hwmA: 8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT6_B_DVAB8_0 (GRAMICIDIN C)	4hwm	UNCHARACTERIZED PROTEIN YEDD (Klebsiella pneumoniae)	4 / 5	GLY A 63 VAL A 59 TRP A 39 TRP A 128	None	1.48A	1nt6B-4hwmA: undetectable	1nt6B-4hwmA: 8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6K_A_ACTA860_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	4hwm	UNCHARACTERIZED PROTEIN YEDD (Klebsiella pneumoniae)	4 / 6	GLY A 34 TRP A 39 VAL A 59 ALA A 31	None	1.02A	1p6kA-4hwmA: undetectable	1p6kA-4hwmA: 14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NQA_H_9CRH501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	4hwm	UNCHARACTERIZED PROTEIN YEDD (Klebsiella pneumoniae)	5 / 12	ILE A 88 ALA A 31 LEU A 35 ALA A 36 ILE A 97	None	1.04A	4nqaH-4hwmA: undetectable	4nqaH-4hwmA: 15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z69_A_DIFA1006_1 (SERUM ALBUMIN)	4hwm	UNCHARACTERIZED PROTEIN YEDD (Klebsiella pneumoniae)	4 / 7	ILE A 88 LEU A 35 GLY A 63 LYS A 80	None	0.96A	4z69A-4hwmA: undetectable	4z69A-4hwmA: 12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JW1_A_CELA602_2 (PROSTAGLANDIN G/H SYNTHASE 2)	4hwm	UNCHARACTERIZED PROTEIN YEDD (Klebsiella pneumoniae)	4 / 6	VAL A 74 LEU A 57 SER A 56 ILE A 107	None	0.88A	5jw1A-4hwmA: undetectable	5jw1A-4hwmA: 12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0W_B_SAMB501_1 (PEPTIDE N-METHYLTRANSFERASE)	4hwm	UNCHARACTERIZED PROTEIN YEDD (Klebsiella pneumoniae)	4 / 5	TYR A 109 SER A 56 ALA A 55 GLN A 77	None	1.14A	5n0wB-4hwmA: undetectable	5n0wB-4hwmA: 15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N4I_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	4hwm	UNCHARACTERIZED PROTEIN YEDD (Klebsiella pneumoniae)	4 / 5	TYR A 109 SER A 56 ALA A 55 GLN A 77	None	1.12A	5n4iA-4hwmA: undetectable	5n4iA-4hwmA: 16.42

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NT6_A_DVAA8_0","GRAMICIDIN C","4hwm","UNCHARACTERIZED PROTEIN YEDD","Klebsiella pneumoniae",4,"GLY A  63;VAL A  59;TRP A  39;TRP A 128","None","1.48A","1nt6A-4hwmA:undetectable","1nt6A-4hwmA:8.70"],["1NT6_B_DVAB8_0","GRAMICIDIN C","4hwm","UNCHARACTERIZED PROTEIN YEDD","Klebsiella pneumoniae",4,"GLY A  63;VAL A  59;TRP A  39;TRP A 128","None","1.48A","1nt6B-4hwmA:undetectable","1nt6B-4hwmA:8.70"],["1P6K_A_ACTA860_0","NITRIC-OXIDE SYNTHASE, BRAIN","4hwm","UNCHARACTERIZED PROTEIN YEDD","Klebsiella pneumoniae",4,"GLY A  34;TRP A  39;VAL A  59;ALA A  31","None","1.02A","1p6kA-4hwmA:undetectable","1p6kA-4hwmA:14.83"],["4NQA_H_9CRH501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","4hwm","UNCHARACTERIZED PROTEIN YEDD","Klebsiella pneumoniae",5,"ILE A  88;ALA A  31;LEU A  35;ALA A  36;ILE A  97","None","1.04A","4nqaH-4hwmA:undetectable","4nqaH-4hwmA:15.14"],["4Z69_A_DIFA1006_1","SERUM ALBUMIN","4hwm","UNCHARACTERIZED PROTEIN YEDD","Klebsiella pneumoniae",4,"ILE A  88;LEU A  35;GLY A  63;LYS A  80","None","0.96A","4z69A-4hwmA:undetectable","4z69A-4hwmA:12.14"],["5JW1_A_CELA602_2","PROSTAGLANDIN G\/H SYNTHASE 2","4hwm","UNCHARACTERIZED PROTEIN YEDD","Klebsiella pneumoniae",4,"VAL A  74;LEU A  57;SER A  56;ILE A 107","None","0.88A","5jw1A-4hwmA:undetectable","5jw1A-4hwmA:12.69"],["5N0W_B_SAMB501_1","PEPTIDE N-METHYLTRANSFERASE","4hwm","UNCHARACTERIZED PROTEIN YEDD","Klebsiella pneumoniae",4,"TYR A 109;SER A  56;ALA A  55;GLN A  77","None","1.14A","5n0wB-4hwmA:undetectable","5n0wB-4hwmA:15.85"],["5N4I_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","4hwm","UNCHARACTERIZED PROTEIN YEDD","Klebsiella pneumoniae",4,"TYR A 109;SER A  56;ALA A  55;GLN A  77","None","1.12A","5n4iA-4hwmA:undetectable","5n4iA-4hwmA:16.42"]]