SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hxq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		4 / 5 GLY A 257
LEU A 236
THR A 253
VAL A 123
 None
 0.96A 1ekjF-4hxqA:
undetectable
1ekjG-4hxqA:
1.8		 1ekjF-4hxqA:
21.78
1ekjG-4hxqA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 902 ( 3.4A)
MN  A 902 ( 2.0A)
None
X8A  A 901 ( 3.7A)
X8A  A 901 (-3.4A)
 1.35A 1v8bA-4hxqA:
2.1		 1v8bA-4hxqA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 902 ( 3.4A)
MN  A 902 ( 2.0A)
None
X8A  A 901 ( 3.7A)
X8A  A 901 (-3.4A)
 1.35A 1v8bB-4hxqA:
2.0		 1v8bB-4hxqA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 902 ( 3.4A)
MN  A 902 ( 2.0A)
None
X8A  A 901 ( 3.7A)
X8A  A 901 (-3.4A)
 1.33A 1v8bD-4hxqA:
undetectable		 1v8bD-4hxqA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 LEU A  37
GLY A  51
GLY A  12
GLY A  98
LYS A  39
 None
 1.10A 1y4lA-4hxqA:
undetectable		 1y4lA-4hxqA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		4 / 8 THR A 131
GLY A 185
THR A 127
ILE A 129
 None
 0.86A 2f9wA-4hxqA:
undetectable
2f9wB-4hxqA:
undetectable		 2f9wA-4hxqA:
23.86
2f9wB-4hxqA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		3 / 3 SER A 137
GLU A 277
ASP A 274
 X8A  A 901 (-2.5A)
X8A  A 901 (-4.0A)
None
 0.81A 2zulA-4hxqA:
undetectable		 2zulA-4hxqA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 4hxq ARGINASE-1
(Homo
sapiens) 		4 / 6 LEU A  97
GLY A  99
LEU A  95
SER A  94
 None
 0.62A 3aiaA-4hxqA:
undetectable		 3aiaA-4hxqA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 902 ( 3.4A)
MN  A 902 ( 2.0A)
None
X8A  A 901 ( 3.7A)
X8A  A 901 (-3.4A)
 1.34A 3ce6D-4hxqA:
undetectable		 3ce6D-4hxqA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		3 / 3 SER A 137
GLU A 277
ASP A 274
 X8A  A 901 (-2.5A)
X8A  A 901 (-4.0A)
None
 0.78A 3dmhA-4hxqA:
undetectable		 3dmhA-4hxqA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 ASP A 274
VAL A 233
GLY A  99
THR A 244
THR A 246
 None
None
None
None
X8A  A 901 (-3.5A)
 0.88A 3el5B-4hxqA:
undetectable		 3el5B-4hxqA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 LEU A 273
LEU A 270
ILE A 264
THR A 267
ILE A 299
 None
 0.97A 3gcsA-4hxqA:
undetectable		 3gcsA-4hxqA:
22.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN0_A_DMOA551_1
(ARGINASE-1)		 4hxq ARGINASE-1
(Homo
sapiens) 		9 / 9 HIS A 126
ASP A 128
ASN A 130
SER A 137
HIS A 141
GLY A 142
ASP A 183
GLU A 186
THR A 246
 MN  A 902 ( 3.4A)
MN  A 903 ( 2.6A)
X8A  A 901 (-4.4A)
X8A  A 901 (-2.5A)
X8A  A 901 (-3.4A)
X8A  A 901 ( 3.7A)
X8A  A 901 (-3.0A)
X8A  A 901 ( 4.3A)
X8A  A 901 (-3.5A)
 0.21A 3gn0A-4hxqA:
58.5		 3gn0A-4hxqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN0_B_DMOB552_1
(ARGINASE-1)		 4hxq ARGINASE-1
(Homo
sapiens) 		9 / 9 HIS A 126
ASP A 128
ASN A 130
SER A 137
HIS A 141
GLY A 142
ASP A 183
GLU A 186
THR A 246
 MN  A 902 ( 3.4A)
MN  A 903 ( 2.6A)
X8A  A 901 (-4.4A)
X8A  A 901 (-2.5A)
X8A  A 901 (-3.4A)
X8A  A 901 ( 3.7A)
X8A  A 901 (-3.0A)
X8A  A 901 ( 4.3A)
X8A  A 901 (-3.5A)
 0.19A 3gn0B-4hxqA:
58.0		 3gn0B-4hxqA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_1
(ADENOSYLHOMOCYSTEINA
SE)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 902 ( 3.4A)
MN  A 902 ( 2.0A)
None
X8A  A 901 ( 3.7A)
X8A  A 901 (-3.4A)
 1.36A 3ondA-4hxqA:
undetectable		 3ondA-4hxqA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_1
(ADENOSYLHOMOCYSTEINA
SE)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 902 ( 3.4A)
MN  A 902 ( 2.0A)
None
X8A  A 901 ( 3.7A)
X8A  A 901 (-3.4A)
 1.35A 3ondB-4hxqA:
2.6		 3ondB-4hxqA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 9 LEU A  36
GLY A  51
ILE A  11
PRO A  28
LEU A  31
 None
 1.04A 3u7sA-4hxqA:
undetectable		 3u7sA-4hxqA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		4 / 8 GLY A 310
TYR A 254
LEU A 258
GLU A 262
 None
 0.85A 4fgzB-4hxqA:
undetectable		 4fgzB-4hxqA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		4 / 8 TYR A 254
LEU A 258
GLU A 262
TYR A 265
 None
 0.57A 4fgzB-4hxqA:
undetectable		 4fgzB-4hxqA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4hxq ARGINASE-1
(Homo
sapiens) 		4 / 6 ASP A 183
ASP A 232
ASP A 128
GLU A 186
 X8A  A 901 (-3.0A)
MN  A 902 (-3.0A)
MN  A 903 ( 2.6A)
X8A  A 901 ( 4.3A)
 1.31A 4gkhJ-4hxqA:
undetectable		 4gkhJ-4hxqA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 SER A  94
LEU A  95
ALA A 104
MET A 276
GLY A  99
 None
 1.34A 4j7xA-4hxqA:
2.7		 4j7xA-4hxqA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 SER A  94
LEU A  95
ASP A 232
MET A 276
GLY A  99
 None
None
MN  A 902 (-3.0A)
None
None
 1.24A 4j7xF-4hxqA:
4.7		 4j7xF-4hxqA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 4hxq ARGINASE-1
(Homo
sapiens) 		4 / 8 LEU A 216
LEU A 229
HIS A 228
ILE A 169
 None
 0.81A 4ok1A-4hxqA:
undetectable		 4ok1A-4hxqA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		3 / 3 ASP A 124
ASP A 128
ASN A 139
 MN  A 903 (-2.5A)
MN  A 903 ( 2.6A)
None
 0.75A 4q5mA-4hxqA:
undetectable		 4q5mA-4hxqA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 4hxq ARGINASE-1
(Homo
sapiens) 		3 / 3 ASP A  49
LEU A  97
GLY A  12
 None
 0.42A 4xmfA-4hxqA:
undetectable		 4xmfA-4hxqA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4hxq ARGINASE-1
(Homo
sapiens) 		4 / 6 SER A 107
HIS A 228
MET A 276
LEU A  95
 None
 1.36A 5dzke-4hxqA:
undetectable
5dzks-4hxqA:
undetectable		 5dzke-4hxqA:
22.19
5dzks-4hxqA:
0.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 ILE A 208
LEU A 252
GLU A 214
ARG A 205
GLY A 207
 None
 1.24A 5k7uA-4hxqA:
1.8		 5k7uA-4hxqA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 902 ( 3.4A)
MN  A 902 ( 2.0A)
None
X8A  A 901 ( 3.7A)
X8A  A 901 (-3.4A)
 1.32A 5m5kB-4hxqA:
undetectable		 5m5kB-4hxqA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 902 ( 3.4A)
MN  A 902 ( 2.0A)
None
X8A  A 901 ( 3.7A)
X8A  A 901 (-3.4A)
 1.37A 5m66A-4hxqA:
undetectable		 5m66A-4hxqA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 902 ( 3.4A)
MN  A 902 ( 2.0A)
None
X8A  A 901 ( 3.7A)
X8A  A 901 (-3.4A)
 1.35A 5m66C-4hxqA:
2.2		 5m66C-4hxqA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		3 / 3 LYS A  88
HIS A 111
HIS A 115
 None
 0.92A 5oexA-4hxqA:
undetectable		 5oexA-4hxqA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		3 / 3 LYS A  88
HIS A 111
HIS A 115
 None
 0.94A 5oexB-4hxqA:
undetectable		 5oexB-4hxqA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		3 / 3 LYS A  88
HIS A 111
HIS A 115
 None
 0.91A 5oexC-4hxqA:
undetectable		 5oexC-4hxqA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 4hxq ARGINASE-1
(Homo
sapiens) 		3 / 3 LYS A  88
HIS A 111
HIS A 115
 None
 0.89A 5oexD-4hxqA:
undetectable		 5oexD-4hxqA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 902 ( 3.4A)
MN  A 902 ( 2.0A)
None
X8A  A 901 ( 3.7A)
X8A  A 901 (-3.4A)
 1.34A 5utuF-4hxqA:
undetectable		 5utuF-4hxqA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_B_HFGB802_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 PRO A 247
THR A 246
GLU A 277
HIS A 141
THR A 127
 None
X8A  A 901 (-3.5A)
X8A  A 901 (-4.0A)
X8A  A 901 (-3.4A)
None
 1.32A 5xioB-4hxqA:
undetectable		 5xioB-4hxqA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 VAL A  84
LEU A  36
LEU A  97
SER A 107
LEU A 270
 None
 1.06A 6b0iB-4hxqA:
4.4		 6b0iB-4hxqA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 VAL A  84
LEU A  36
LEU A  97
SER A 107
LEU A 270
 None
 1.01A 6b0lB-4hxqA:
undetectable		 6b0lB-4hxqA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 LEU A  31
SER A 107
VAL A  84
ILE A  11
ASP A  49
 None
 1.18A 6bxmA-4hxqA:
2.1		 6bxmA-4hxqA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 LEU A  31
SER A 107
VAL A  84
ILE A  11
ASP A  49
 None
 1.26A 6bxnA-4hxqA:
2.3		 6bxnA-4hxqA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4hxq ARGINASE-1
(Homo
sapiens) 		6 / 12 ALA A  34
LEU A  37
SER A  94
VAL A  87
THR A 300
LEU A 301
 None
 1.33A 6djzC-4hxqA:
undetectable		 6djzC-4hxqA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_1
(-)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 902 ( 3.4A)
MN  A 902 ( 2.0A)
None
X8A  A 901 ( 3.7A)
X8A  A 901 (-3.4A)
 1.32A 6f3nB-4hxqA:
2.5		 6f3nB-4hxqA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 4hxq ARGINASE-1
(Homo
sapiens) 		5 / 9 LEU A 118
VAL A 120
SER A 146
LEU A 149
ILE A 174
 None
 1.29A 6fdyU-4hxqA:
undetectable		 6fdyU-4hxqA:
22.15