SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hy7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 4hy7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Triticum
aestivum) 		3 / 3 TYR A  55
GLY A  57
PHE A  74
 None
 0.64A 2m2pB-4hy7A:
undetectable		 2m2pB-4hy7A:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 4hy7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Triticum
aestivum) 		4 / 8 GLY A  82
CYH A 168
GLY A  71
PHE A  60
 None
 0.98A 3ko0O-4hy7A:
undetectable
3ko0Q-4hy7A:
undetectable		 3ko0O-4hy7A:
21.12
3ko0Q-4hy7A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4hy7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Triticum
aestivum) 		4 / 6 TYR A  55
HIS A  54
VAL A 164
PHE A 119
 None
 1.20A 4a97E-4hy7A:
undetectable		 4a97E-4hy7A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 4hy7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Triticum
aestivum) 		5 / 12 GLY A 116
ILE A  85
ASN A 109
PHE A  36
LEU A 105
 None
 1.08A 5fa8A-4hy7A:
undetectable		 5fa8A-4hy7A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4hy7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Triticum
aestivum) 		4 / 6 PHE A  67
CYH A 122
SER A 106
HIS A 133
 None
 1.49A 5ycnA-4hy7A:
undetectable		 5ycnA-4hy7A:
22.01