SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hz9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_A_IPHA2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 4hz9 PUTATIVE CYTOPLASMIC
PROTEIN
(Ralstonia
pickettii) 		4 / 5 HIS A  81
TYR A 106
TYR A 113
PRO A 111
 None
 1.29A 2ombA-4hz9A:
undetectable
2ombB-4hz9A:
undetectable		 2ombA-4hz9A:
19.23
2ombB-4hz9A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 4hz9 PUTATIVE CYTOPLASMIC
PROTEIN
(Ralstonia
pickettii) 		3 / 3 SER A  88
ASP A  86
ASN A   9
 None
 1.01A 3lsfB-4hz9A:
undetectable
3lsfE-4hz9A:
undetectable		 3lsfB-4hz9A:
17.96
3lsfE-4hz9A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 4hz9 PUTATIVE CYTOPLASMIC
PROTEIN
(Ralstonia
pickettii) 		3 / 3 ASP A  86
ASN A   9
SER A  88
 None
 0.96A 3lsfB-4hz9A:
undetectable
3lsfE-4hz9A:
undetectable		 3lsfB-4hz9A:
17.96
3lsfE-4hz9A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 4hz9 PUTATIVE CYTOPLASMIC
PROTEIN
(Ralstonia
pickettii) 		5 / 9 VAL A  68
GLY A  55
PHE A  56
SER A  50
GLY A  48
 None
 1.33A 4mm5A-4hz9A:
undetectable		 4mm5A-4hz9A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 4hz9 PUTATIVE CYTOPLASMIC
PROTEIN
(Ralstonia
pickettii) 		5 / 9 VAL A  68
GLY A  55
PHE A  56
SER A  50
GLY A  48
 None
 1.26A 4mmbA-4hz9A:
undetectable		 4mmbA-4hz9A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 4hz9 PUTATIVE CYTOPLASMIC
PROTEIN
(Ralstonia
pickettii) 		5 / 9 VAL A  68
GLY A  55
PHE A  56
SER A  50
GLY A  48
 None
 1.42A 4mmeA-4hz9A:
undetectable		 4mmeA-4hz9A:
11.35