SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i0k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 4i0k CD276 ANTIGEN
(Mus
musculus) 		3 / 3 ASP A 116
ARG A 113
ASP A  45
 None
SO4  A 306 (-2.4A)
None
 0.81A 4fp9D-4i0kA:
undetectable		 4fp9D-4i0kA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 4i0k CD276 ANTIGEN
(Mus
musculus) 		3 / 3 ASP A 116
ARG A 113
ASP A  45
 None
SO4  A 306 (-2.4A)
None
 0.76A 4fzvA-4i0kA:
undetectable		 4fzvA-4i0kA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 4i0k CD276 ANTIGEN
(Mus
musculus) 		3 / 3 ASP A 116
ARG A 113
ASP A  45
 None
SO4  A 306 (-2.4A)
None
 0.62A 5zvgA-4i0kA:
undetectable		 5zvgA-4i0kA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 4i0k CD276 ANTIGEN
(Mus
musculus) 		3 / 3 ASP A 116
ARG A 113
ASP A  45
 None
SO4  A 306 (-2.4A)
None
 0.64A 5zvgB-4i0kA:
undetectable		 5zvgB-4i0kA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 4i0k CD276 ANTIGEN
(Mus
musculus) 		4 / 5 LEU A 212
LEU A 208
THR A 217
PRO A 145
 None
None
SO4  A 307 (-4.4A)
None
 0.92A 6ew0F-4i0kA:
undetectable		 6ew0F-4i0kA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 4i0k CD276 ANTIGEN
(Mus
musculus) 		4 / 6 LEU A 212
LEU A 208
THR A 217
PRO A 145
 None
None
SO4  A 307 (-4.4A)
None
 0.92A 6ew0G-4i0kA:
undetectable		 6ew0G-4i0kA:
16.35