SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i0o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4i0o PROTEIN ELYS
(Mus
musculus) 		3 / 3 GLN A 179
HIS A 210
ARG A 209
 None
 1.01A 1zlqA-4i0oA:
0.5		 1zlqA-4i0oA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 4i0o PROTEIN ELYS
(Mus
musculus) 		4 / 6 ARG A 457
ASP A 403
ILE A 404
GLU A 276
 None
 1.40A 2ya7C-4i0oA:
6.6		 2ya7C-4i0oA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 4i0o PROTEIN ELYS
(Mus
musculus) 		3 / 3 GLN A  53
THR A  19
LEU A 111
 None
 0.72A 3ondA-4i0oA:
undetectable		 3ondA-4i0oA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 4i0o PROTEIN ELYS
(Mus
musculus) 		3 / 3 GLN A  53
THR A  19
LEU A 111
 None
 0.71A 3ondB-4i0oA:
undetectable		 3ondB-4i0oA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4i0o PROTEIN ELYS
(Mus
musculus) 		5 / 12 GLY A 242
ASP A 241
ILE A 223
VAL A 159
TYR A 257
 None
 1.12A 4a81A-4i0oA:
undetectable		 4a81A-4i0oA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 4i0o PROTEIN ELYS
(Mus
musculus) 		4 / 5 VAL A 197
LEU A 211
LEU A 152
ILE A 193
 None
 0.98A 4a9jA-4i0oA:
undetectable		 4a9jA-4i0oA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 4i0o PROTEIN ELYS
(Mus
musculus) 		4 / 5 VAL A 197
LEU A 211
LEU A 152
ILE A 193
 None
 0.92A 4a9jB-4i0oA:
undetectable		 4a9jB-4i0oA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 4i0o PROTEIN ELYS
(Mus
musculus) 		4 / 5 VAL A 197
LEU A 211
LEU A 152
ILE A 193
 None
 0.90A 4a9jC-4i0oA:
undetectable		 4a9jC-4i0oA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 4i0o PROTEIN ELYS
(Mus
musculus) 		5 / 12 ALA A  46
LEU A  45
LEU A 111
TYR A 109
ILE A  96
 None
 0.94A 4g1bA-4i0oA:
undetectable		 4g1bA-4i0oA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 4i0o PROTEIN ELYS
(Mus
musculus) 		4 / 5 GLU A 274
ARG A 231
PRO A 376
SER A 379
 None
 0.96A 4k17B-4i0oA:
undetectable		 4k17B-4i0oA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 4i0o PROTEIN ELYS
(Mus
musculus) 		4 / 5 GLU A 274
SER A 379
ARG A 231
PRO A 376
 None
 1.16A 4k17B-4i0oA:
undetectable		 4k17B-4i0oA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 4i0o PROTEIN ELYS
(Mus
musculus) 		5 / 12 GLN A  53
ALA A  22
GLY A  24
GLU A  27
LEU A  34
 None
 1.21A 5vlmF-4i0oA:
undetectable		 5vlmF-4i0oA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 4i0o PROTEIN ELYS
(Mus
musculus) 		4 / 6 PHE A  38
GLY A  44
ASN A  43
LYS A  42
 None
 0.80A 5x24A-4i0oA:
undetectable		 5x24A-4i0oA:
23.74