SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i16'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 4i16 CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 11
(Mus
musculus) 		4 / 8 LEU A  33
ASN A  71
LEU A  76
LEU A  77
 None
 0.94A 1e7cA-4i16A:
undetectable		 1e7cA-4i16A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 4i16 CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 11
(Mus
musculus) 		4 / 8 PHE A  91
SER A  34
ILE A  37
LEU A  77
 None
 0.64A 1eupA-4i16A:
undetectable		 1eupA-4i16A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 4i16 CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 11
(Mus
musculus) 		4 / 7 VAL A  90
VAL A  26
TYR A  36
CYH A  49
 None
 1.27A 1t46A-4i16A:
undetectable		 1t46A-4i16A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPW_A_OTCA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 4i16 CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 11
(Mus
musculus) 		5 / 12 LEU A  46
PHE A  91
ARG A  72
PRO A  39
VAL A  60
 None
None
SO4  A 202 ( 3.0A)
None
None
 1.48A 2xpwA-4i16A:
undetectable		 2xpwA-4i16A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4i16 CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 11
(Mus
musculus) 		4 / 4 PRO A 100
LEU A 102
ILE A  37
ARG A  72
 None
None
None
SO4  A 202 ( 3.0A)
 1.46A 4f4dA-4i16A:
undetectable		 4f4dA-4i16A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4i16 CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 11
(Mus
musculus) 		4 / 7 VAL A  51
ILE A  52
LEU A  33
LEU A  77
 None
 0.89A 4l1wA-4i16A:
undetectable		 4l1wA-4i16A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA406_0
(FAD:PROTEIN FMN
TRANSFERASE)		 4i16 CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 11
(Mus
musculus) 		4 / 5 SER A  34
ARG A  30
LEU A  77
ASP A  78
 None
 1.24A 4xdtA-4i16A:
undetectable		 4xdtA-4i16A:
15.75