SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 4i1q BRIDGING INTEGRATOR
2
(Homo
sapiens) 		3 / 3 TYR A 221
PHE A  67
ARG A 217
 None
 0.93A 4g19D-4i1qA:
undetectable		 4g19D-4i1qA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4i1q BRIDGING INTEGRATOR
2
(Homo
sapiens) 		4 / 4 LYS A 226
LEU A 227
GLU A 223
LEU A 109
 None
 1.43A 4k4yE-4i1qA:
undetectable		 4k4yE-4i1qA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 4i1q BRIDGING INTEGRATOR
2
(Homo
sapiens) 		4 / 7 VAL A 103
GLN A  86
LEU A  99
GLU A  97
 None
 0.73A 4zphA-4i1qA:
undetectable
4zphB-4i1qA:
0.0		 4zphA-4i1qA:
18.25
4zphB-4i1qA:
20.98